MycoData

Grifola Frondosa, the king of mushrooms, is one of the most valued traditional medicines and has been used as a health food for a long time in China, Japan, and other Asian countries..

OncologyImmune supportMetabolic health

High relevance

Enoki · 2019 · Journal Article · International journal of medicinal mushrooms

Wound Healing Activity of a Skin Substitute from Residues of Culinary-Medicinal Winter Mushroom Flammulina velutipes (Agaricomycetes) Cultivation.

A skin substitute TG05 obtained from residues of the culinary-medicinal mushroom Flammulina velutipes cultivation process was developed in this study for the first time..

Energy & fatigueMetabolic healthSkin & hydration

High relevance

Lion's Mane · 2019 · Journal Article · Biological & pharmaceutical bulletin

X-Ray Crystallographic Structure of Hericium erinaceus Ribonuclease, RNase He1 in Complex with Zinc

RNase He1 is a guanylic acid-specific ribonuclease of the RNase T1 family from Hericium erinaceus (Japanese name: Yamabushitake). Its RNA degrading activity is strongly inhibited by Zn2+, similar to other T1 family RNases..

Oncology

High relevance

Cordyceps · 2019 · Research Article · Medicines (Basel, Switzerland)

Xanthine Oxidase Inhibitory Potential, Antioxidant and Antibacterial Activities of Cordyceps militaris (L.) Link Fruiting Body.

Background: Cordyceps militaris is a medicinal mushroom and has been extensively used as a folk medicine in East Asia. In this study, the separation of constituents involved in xanthine oxidase (XO) inhibitory, antioxidant and antibacterial properties of C.

High relevance

Cordyceps · 2019 · Journal Article · Pest management science

XRN1-associated long non-coding RNAs may contribute to fungal virulence and sexual development in entomopathogenic fungus Cordyceps militaris.

BACKGROUND: Numerous long non-coding RNAs (lncRNAs) identified and characterized in mammals, plants, and fungi have been found to play critical regulatory roles in biological processes. However, little is known about the role of lncRNAs in insect pathogenic fungi..

Energy & fatigue

High relevance

Oyster Mushroom · 2018 · Journal Article · Voprosy pitaniia

[The influence of the drying method for food properties and hypolidemic potential of oyster mushrooms (Pleurotus ostreatus)].

The aim of this research was to study the influence of two drying methods: freeze-drying sublimation and dry-air drying on the selected nutritional properties and hypolipidemic potential of fruiting bodies of oyster mushroom (Pleurotus ostreatus)..

Immune supportMetabolic healthSkin & hydration

High relevance

Cordyceps · 2018 · Research Article · Toxicology research

A 90-day subchronic toxicity study of submerged mycelial culture of Cordyceps militaris in rats.

Cordyceps militaris (C. militaris) is a parasitic fungus that grows on the larvae of Lepidoptera.

Immune supportMetabolic health

High relevance

Lion's Mane · 2018 · Journal Article · International journal of biological macromolecules

A novel core 1 O-linked glycan-specific binding lectin from the fruiting body of Hericium erinaceus.

Mucin-type O-glycans are involved in biological functions on the cell surface as well as the glycoproteins and can also be used as specific carbohydrate biomarkers of many diseases..

High relevance

Cordyceps · 2018 · Research Article · Journal of food and drug analysis

A novel protein from edible fungi Cordyceps militaris that induces apoptosis.

Cordyceps militaris is a dietary therapeutic fungus that is an important model species in Cordyceps research. In this study, we purified a novel protein from the fruit bodies of C.

OncologyEnergy & fatigueLiver support

High relevance

King Oyster · 2018 · Journal Article · International journal of phytoremediation

Alleviatory effect of spent Pleurotus eryngii Quel substrate on replant problem of Rehmannia glutinosa Libosch.

Rehmannia glutinosa Libosch. is a medicinal plant cultivated at a commercial scale in China.

High relevance

Cordyceps · 2018 · Research Article · Saudi journal of biological sciences

Anti-tumor and anti-metastatic roles of cordycepin, one bioactive compound of Cordyceps militaris.

Public interest in complementary and alternative medicine has been increased worldwide, due to its wide applications in cancer prevention and treatment. Cordycepin is one of the most common and crucial types of complementary and alternative medicine..

Oncology

High relevance

Cordyceps · 2018 · Research Article · Oxidative medicine and cellular longevity

Antioxidant and Hypoglycemic Effects of Acidic-Extractable Polysaccharides from Cordyceps militaris on Type 2 Diabetes Mice.

The present work was performed to evaluate the effect of acidic-extractable polysaccharides (AE-PS) from fruit bodies of Cordyceps militaris on type 2 diabetes mellitus (T2DM) and its structural characteristics..

Immune supportMetabolic healthLiver support

High relevance

King Oyster · 2018 · Journal Article · International journal of biological macromolecules

Antioxidation, anti-hyperglycaemia and renoprotective effects of extracellular polysaccharides from Pleurotus eryngii SI-04.

The present study was designed to investigate the anti-hyperglycaemia, hypolipidemia and renoprotective effects of two extracellular polysaccharides (EPS) from the broth of Pleurotus eryngii SI-04 (EPS1 and EPS2) in mice with streptozotocin (STZ)-induced diabetic nephropathy (DN)..

Immune supportMetabolic health

High relevance

Reishi · 2018 · Journal Article · International journal of medicinal mushrooms

Antiproliferative Effects of a Triterpene-Enriched Extract from Lingzhi or Reishi Medicinal Mushroom, Ganoderma lucidum (Agaricomycetes), on Human Lung Cancer Cells.

Ganoderma lucidum, a mushroom that has been used to treat disease in East Asia for centuries, has been shown to be effective against many types of tumors, but the exact cellular mechanism of action is unknown..

OncologyImmune supportRespiratory

High relevance

Cordyceps · 2018 · Research Article · Journal of diabetes research

Artificially Cultivated Ophiocordyceps sinensis Alleviates Diabetic Nephropathy and Its Podocyte Injury via Inhibiting P2X7R Expression and NLRP3 Inflammasome Activation.

BACKGROUND/AIMS: It is known that chronic low-grade inflammation contributes to the initiation and development of both diabetes and diabetic nephropathy (DN), so we designed this study to investigate the role of P2X7R and NLRP3 inflammasome in DN pathogenesis and the antagonistic effects of artificially cultivated….

Immune supportMetabolic health

High relevance

Oyster Mushroom · 2018 · Journal Article · International journal of medicinal mushrooms

Bioaccumulation of Lithium (Li2CO3) in Mycelia of the Culinary-Medicinal Oyster Mushroom, Pleurotus ostreatus (Agaricomycetes).

Pleurotus ostreatus is a white-rot mushroom that bioaccumulates metals in basidiocarps and vegetative mycelia. This fungus has been used in soil and water bioremediation of several heavy metals; however, there are few studies of lithium mycelial bioaccumulation for pharmacological use..

Liver support

High relevance

Chaga · 2018 · Journal Article · Journal of ethnopharmacology

Bioactivity-based analysis and chemical characterization of cytotoxic constituents from Chaga mushroom (Inonotus obliquus) that induce apoptosis in human lung adenocarcinoma cells.

ETHNOPHARMACOLOGICAL RELEVANCE: Inonotus obliquus, also known as Chaga mushroom, is one of the most widely appreciated wild edible mushrooms in Russia and northern European countries and is renowned for its use in cancer treatment..

OncologyImmune supportRespiratory

High relevance

Oyster Mushroom · 2018 · Research Article · Food science & nutrition

Bioprospecting of powdered pineapple rind as an organic supplement of composted sawdust for Pleurotus ostreatus mushroom cultivation.

Pineapple rind is a by-product of the pineapple processing industry and contains nutrients and other compounds which must be utilized as a bioresource for socio-economic benefits while preventing the potential problems of improper agroindustrial biomass disposal methods..

Metabolic healthGut & microbiome

High relevance

Wood Ear · 2018 · Journal Article · Chemical communications (Cambridge, England)

Carboxylic and O-acetyl moieties are essential for the immunostimulatory activity of glucuronoxylomannan: a novel TLR4 specific immunostimulator from Auricularia auricula-judae.

This study established the comprehensive repeating unit structure of immunologically active glucuronoxylomannan (AAPS) from wood ear mushroom, Auricularia auricula-judae..

Immune support

High relevance

King Oyster · 2018 · Research Article · Oxidative medicine and cellular longevity

Characterization and Attenuation of Streptozotocin-Induced Diabetic Organ Damage by Polysaccharides from Spent Mushroom Substrate (Pleurotus eryngii).

The aim of this work was to characterize spent mushroom substrate polysaccharides (MSP) from Pleurotus eryngii and their antioxidant and organ protective effects in streptozotocin- (STZ-) induced diabetic mice. The enzymatic-, acidic-, and alkalic- (En-, Ac-, and Al-) MSP were extracted from P..

Immune supportMetabolic healthLiver support

High relevance

King Oyster · 2018 · Journal Article · International journal of food science & technology

Chemical characterisation and hypolipidaemic effects of two purified Pleurotus eryngii polysaccharides

This study is focused on the isolation and characterisation of two purified polysaccharide fractions (namely PPEP‐1 and PPEP‐2) from Pleurotus eryngii (P. eryngii) and evaluation of their hypolipidaemic effects.

Immune supportMetabolic health

High relevance

Chaga · 2018 · Research Article · Molecules (Basel, Switzerland)

Chemical Characterization and Hypoglycaemic Activities In Vitro of Two Polysaccharides from Inonotus obliquus by Submerged Culture.

Polysaccharides from the fungus Inonotus obliquus have been found to be biologically active. In this study, we carried out a preliminary characterisation and assessment of the hypoglycaemic activities of the polysaccharides (IOEP) from Inonotus obliquus obtained by liquid fermentation..

Immune supportMetabolic health

High relevance

King Oyster · 2018 · Journal Article · Applied microbiology and biotechnology

Classification of fungal glucuronoyl esterases (FGEs) and characterization of two new FGEs from Ceriporiopsis subvermispora and Pleurotus eryngii.

Fungal glucuronoyl esterases (FGEs) catalyze cleavage of the ester bond connecting a lignin alcohol to the xylan-bound 4-O-methyl-D-glucuronic acid of glucuronoxylans..

High relevance

Cordyceps · 2018 · Journal Article · Enzyme and microbial technology

Cloning and protein expression of the sn-1(3) regioselective lipase from Cordyceps militaris.

In this study, the gene of a novel lipase with sn-1(3) regioselectivity (i.e., sn-1 or sn-3 specific) from Cordyceps militaris was successfully expressed by a heterologous expression system. Total RNA was extracted from C.

Respiratory

High relevance

Cordyceps · 2018 · Research Article · Frontiers in microbiology

Comparative Transcriptome Analysis Between a Spontaneous Albino Mutant and Its Sibling Strain of Cordyceps militaris in Response to Light Stress.

Albinism has been used for new variety screening in some edible mushrooms and the underlying mechanisms are fascinating. Albino fruiting body of Cordyceps militaris, a well-known edible fungus and model organism for Cordyceps, has the potential to be a nutraceutical or functional food due to its high content of….

High relevance

Snow Fungus · 2018 · Journal Article · International journal of food science & technology

Comparison of structural, antioxidant and immuno‐stimulating activities of polysaccharides from Tremella fuciformis in two different regions of China

In this study, we compared the chemical structure, antioxidant and immuno‐stimulating activities of two polysaccharides, TPS–FJ and TPS–SC, extracted from Tremella fuciformis from two of the major cultivation regions of China. TPS–FJ and TPS–SC contained protein and high uronic acid..

OncologyImmune supportGut & microbiome

High relevance

Reishi · 2018 · Journal Article · International journal of medicinal mushrooms

Computational Insights into the Molecular Mechanism of the High Immunomodulatory Activity of LZ-8 Protein Isolated from the Lingzhi or Reishi Medicinal Mushroom Ganoderma lucidum (Agaricomycetes).

Ling zhi-8 (LZ-8) is the first fungal immunomodulatory protein (FIP) isolated from the lingzhi or reishi medicinal mushroom, Ganoderma lucidum. LZ-8 effectively induces interleukin 2 expression and secretion by forming a stable homodimer, and it is regarded as a good candidate to become a new therapeutic agent and/or….

Immune support

High relevance

Reishi · 2018 · Journal Article · International journal of medicinal mushrooms

Conditions Affecting Lingzhi or Reishi Medicinal Mushroom Ganoderma lucidum (Agaricomycetes) Basidiome Quality, Morphogenesis, and Biodegradation of Wood By-products in Argentina.

Solid-state fermentation (SSF) with the medicinal higher Basidiomycete Ganoderma lucidum was studied as a strategy to use pine (Pinus radiata D. Don) and poplar (Populus nigra L.) wood chips and sawdust.

High relevance

Cordyceps · 2018 · Research Article · Frontiers in microbiology

Cordycepin, a Characteristic Bioactive Constituent in Cordyceps militaris, Ameliorates Hyperuricemia through URAT1 in Hyperuricemic Mice.

Recently, we've reported the anti-hyperuricemic effects of Cordyceps militaris. As a characteristic compound of C.

Energy & fatigueLiver support

High relevance

Cordyceps · 2018 · Research Article · Pharmacognosy magazine

Cordyceps militaris Fraction induces apoptosis and G2/M Arrest via c-Jun N-Terminal kinase signaling pathway in oral squamous carcinoma KB Cells.

BACKGROUND: Cordyceps militaris fraction (CMF) has been shown to possess in vitro antitumor activity against human chronic myeloid leukemia K562 cells in our previous research. MATERIALS AND METHODS: The in vitro inhibitory activities of CMF on the growth of KB cells were evaluated by viability assay..

Oncology

High relevance

Cordyceps · 2018 · Research Article · Oncology letters

Cordyceps militaris fraction inhibits the invasion and metastasis of lung cancer cells through the protein kinase B/glycogen synthase kinase 3β/β-catenin signaling pathway.

Cordyceps militaris is widely used as a traditional Chinese medicine health supplement, and is also used in the development of anticancer agents. In our previous studies, it was revealed that C..

OncologyEnergy & fatigueLiver supportSkin & hydration

High relevance

Cordyceps · 2018 · Research Article · Nutrients

Cordyceps militaris Grown on Germinated Soybean Suppresses KRAS-Driven Colorectal Cancer by Inhibiting the RAS/ERK Pathway.

Cordyceps militaris is a commonly used medicinal mushroom containing various therapeutic effects such as anti-inflammatory, anti-allergic, and anti-cancer activities..

OncologyImmune supportRespiratory

High relevance

Cordyceps · 2018 · Journal Article · International journal of medicinal mushrooms

Cosmetic and Skincare Benefits of Cultivated Mycelia from the Chinese Caterpillar Mushroom, Ophiocordyceps sinensis (Ascomycetes).

Mushrooms are potential sources of novel natural cosmeceutical ingredients. This study was conducted to evaluate the cosmetic (skincare) benefits of the valuable medicinal species Ophiocordyceps sinensis (=Cordyceps sinensis).

Skin & hydration

High relevance

Reishi · 2018 · Journal Article · International journal of medicinal mushrooms

Determination of the Biological Efficiency and Antioxidant Potential of Lingzhi or Reishi Medicinal Mushroom, Ganoderma lucidum (Agaricomycetes), Cultivated Using Different Agro-Wastes in Malaysia.

This study investigates the cultivation of Ganoderma lucidum using different agricultural biomasses from Malaysia. Five different combinations of rubber wood sawdust, empty fruit bunch fiber, and mesocarp fiber from oil palm, alone and in combination, were used to cultivate G.

High relevance

King Oyster · 2018 · Journal Article · Fish & shellfish immunology

Dietary administration of eryngii mushroom (Pleurotus eryngii) powder on haemato-immunological responses, bactericidal activity of skin mucus and growth performance of koi carp fingerlings (Cyprinus carpio koi).

The aim of present study was to evaluate the effects of edible eryngii mushroom powder, Pleurotus eryngii (PE), for 63 days on haematological parameters, the serum immune responses, skin mucus, bactericidal activity, stress resistance, growth performance and digestive enzyme activities of Koi carp fingerlings….

Immune supportEnergy & fatigueGut & microbiomeSkin & hydration

High relevance

Lion's Mane · 2018 · Journal Article · International journal of medicinal mushrooms

Dietary Supplementation of Lion's Mane Medicinal Mushroom, Hericium erinaceus (Agaricomycetes), and Spatial Memory in Wild-Type Mice.

Hericium erinaceus is an edible and medicinal mushroom with potential neuroprotective effects. The study of H.

Cognition & nerves

High relevance

Cordyceps · 2018 · Journal Article · International journal of medicinal mushrooms

Effects of a Commercial Supplement of Ophiocordyceps sinensis and Ganoderma lucidum on Physiological Responses to Maximal Exercise in Healthy Young Participants.

Cordyceps sinensis (=Ophiocordyceps sinensis) and Ganoderma lucidum are 2 medicinal mushrooms that have been suggested to have the potential to enhance exercise capacity. We used a commercial supplement combining a traditional Chinese medicine and G..

Energy & fatigueRespiratory

High relevance

Cordyceps · 2018 · Research Article · Journal of food science and technology

Effects of Cordyceps militaris (L.) Fr. fermentation on the nutritional, physicochemical, functional properties and angiotensin I converting enzyme inhibitory activity of red bean (Phaseolus angularis [Willd.] W.F. Wight.) flour.

The effects of solid-state fermentation with Cordyceps militaris (L.) Fr. on the nutritional, physicochemical, and functional properties as well as angiotensin I converting enzyme (ACE) inhibitory activity of red bean (Phaseolus angularis [Willd.] W.F.

Gut & microbiome

High relevance

Cordyceps · 2018 · Research Article · Polymers

Effects of Different Temperatures on the Chemical Structure and Antitumor Activities of Polysaccharides from Cordyceps militaris.

The effects of different extraction temperatures (4 and 80 °C) on the physicochemical properties and antitumor activity of water soluble polysaccharides (CMPs-4 and CMPs-80) from Cordyceps militaris (C. militaris) were evaluated in this study..

OncologyImmune supportEnergy & fatigueMetabolic health

High relevance

Cordyceps · 2018 · Research Article · Journal of animal science

Effects of spent mushroom Cordyceps militaris supplementation on apparent digestibility, rumen fermentation, and blood metabolite parameters of goats.

The objective of this experiment was to study the effects of dried spent mushroom Cordyceps militaris (SMCM) supplementation on digestibility, rumen fermentation, and blood metabolite parameters in goats. When the mushroom production and harvesting was complete, SMCM was collected fresh from a mushroom farm..

Energy & fatigueMetabolic healthGut & microbiome

High relevance

Cordyceps · 2018 · Journal Article · International journal of medicinal mushrooms

Effects of Various Treatments on Extraction of the Main Bioactive Components and Determination of Biological Activity of Extracts from the Caterpillar Medicinal Mushroom Cordyceps militaris (Ascomycetes).

In this study we optimized the extraction of cordycepin from Cordyceps militaris through the use of an orthogonal test based on single-factor experiments. The results showed that the largest amount of cordycepin (1260.28 ± 46.38 μ.g/g) was achieved with an extraction time of 15 minutes, an extraction temperature of….

Immune support

High relevance

Cordyceps · 2018 · Research Article · Frontiers in microbiology

Efficient CRISPR-Cas9 Gene Disruption System in Edible-Medicinal Mushroom Cordyceps militaris.

Cordyceps militaris is a well-known edible medicinal mushroom in East Asia that contains abundant and diverse bioactive compounds. Since traditional genome editing systems in C..

High relevance

Cordyceps · 2018 · Journal Article · Bioresource technology

Enhancing cordycepin production in liquid static cultivation of Cordyceps militaris by adding vegetable oils as the secondary carbon source.

This study evaluated different vegetable oils as the second carbon source in liquid static culture of Cordyceps militaris in terms of mycelial growth and cordycepin production. The maximum mycelial concentration and cordycepin production were observed under cottonseed oil and peanut oil induction, respectively..

Metabolic health

High relevance

Enoki · 2018 · Journal Article · International journal of food science & technology

Enzymatic hydrolysis combined with high‐pressure homogenisation for the preparation of polysaccharide‐based nanoparticles from the by‐product of Flammulina velutipes

In this study, protease, α‐amylase and 5‰ β‐glucanase enzymolysis in combination with high‐pressure homogenisation were used for the preparation of polysaccharide‐based nanoparticles from Flammulina velutipes stipes, respectively, named FNP‐1, FNP‐2 and FNP‐3, and the nanoparticles were subsequently characterised..

Immune supportMetabolic healthSkin & hydration

High relevance

King Oyster · 2018 · Research Article · Journal of food science and technology

Evaluation of 1-methylcyclopropene (1-MCP) treatment combined with nano-packaging on quality of pleurotus eryngii.

The aim of the present study was to investigate the effect of 1-methylcyclopropene (1-MCP) combined with nano-packaging on quality of pleurotus eryngii stored at 4 ± 1 °C for 12 days..

High relevance

Reishi · 2018 · Journal Article · International journal of medicinal mushrooms

Evaluation of the Antioxidative and Hypo-cholesterolemic Effects of Lingzhi or Reishi Medicinal Mushroom, Ganoderma lucidum (Agaricomycetes), in Ameliorating Cardiovascular Disease.

Oxidative stress (OS) and hypercholesterolemia have been linked with a heightened risk of cardiovascular disease (CVD). Because of the numerous drawbacks of synthetic antioxidants and cholesterol-lowering drugs, natural antioxidative and hypocholesterolemic agents are of immense importance..

Energy & fatigueMetabolic healthLiver support

High relevance

Cordyceps · 2018 · Research Article · Microbial cell factories

Expression of a recombinant hybrid antimicrobial peptide magainin II-cecropin B in the mycelium of the medicinal fungus Cordyceps militaris and its validation in mice.

BACKGROUND: Antibiotic residues can cause antibiotic resistance in livestock and their food safety-related issues have increased the consumer demand for products lacking these residues. Hence, developing safe and effective antibiotic alternatives is important to the animal feed industry..

Immune supportGut & microbiome

High relevance

Turkey Tail · 2018 · Journal Article · Journal of biotechnology

Extracellular biosynthesis of biocompatible cadmium sulfide quantum dots using Trametes versicolor.

Quantum dots are important fluorescent semiconductor nano-crystals with distinguished electrical and optical properties and have gained great interest in many fields..

Energy & fatigueSkin & hydration

High relevance

King Oyster · 2018 · Journal Article · International journal of medicinal mushrooms

Extraction of Ergothioneine from Pleurotus eryngii and P. citrinopileatus (Agaricomycetes) and Preparation of Its Product.

Ergothioneine is an effective antioxidant and is abundant in species of genus Pleurotus. This research focused on developing an ergothioneine extract from P.

Gut & microbiome

High relevance

Cordyceps · 2018 · Journal Article · Lebensmittel-Wissenschaft + [i.e. und] Technologie. Food science + technology. Science + technologie alimentaire

Fermenting liquid vinegar with higher taste, flavor and healthy value by using discarded Cordyceps militaris solid culture medium

Cordyceps militaris has entered a large-scale artificial cultivation, and the solid culture medium of Cordyceps militaris are usually discarded. In this study, two kinds of liquid vinegars were prepared with discarded solid culture medium of Cordyceps militaris and rice, respectively..