MycoData

Agaricus blazei Murill is an edible mushroom of the Basidiomycetes family, which has been found to contain a number of compounds with antitumor properties, such as proteoglycans and ergosterol..

Oncology

High relevance

Cordyceps · 2017 · Journal Article · Applied microbiology and biotechnology

DASH-type cryptochromes regulate fruiting body development and secondary metabolism differently than CmWC-1 in the fungus Cordyceps militaris.

Cryptochromes (CRYs) belong to the photolyase/cryptochrome flavoprotein family, which is widely distributed in all kingdoms. A phylogenetic analysis indicated that three Cordyceps militaris proteins [i.e., cryptochrome DASH (CmCRY-DASH), (6-4) photolyase, and cyclobutane pyrimidine dimer (CPD) class I photolyase]….

High relevance

Oyster Mushroom · 2017 · Research Article · AMB Express

Degradation of aflatoxin B1 from naturally contaminated maize using the edible fungus Pleurotus ostreatus.

Aflatoxins are highly carcinogenic secondary metabolites that can contaminate approximately 25% of crops and that cause or exacerbate multiple adverse health conditions, especially in Sub-Saharan Africa and South and Southeast Asia. Regulation and decontamination of aflatoxins in high exposure areas is lacking..

High relevance

Cordyceps · 2017 · Research Article · Frontiers in microbiology

Detection of Ophiocordyceps sinensis and Its Common Adulterates Using Species-Specific Primers.

Ophiocordyceps sinensis is a fungus that infects Hepialidae caterpillars, mummifying the larvae and producing characteristic fruiting bodies (stromata) that are processed into one of the most valued traditional Chinese medicines (TCM)..

High relevance

Cordyceps · 2017 · Research Article · Mycology

Determination and comparative analysis of 13 nucleosides and nucleobases in natural fruiting body of Ophiocordyceps sinensis and its substitutes.

Nucleosides and nucleobases are one of the most important indicators of quality control. A sensitive and reliable high performance liquid chromatography-ultraviolet method was applied to analyse 13 nucleosides and nucleobases simultaneously in 15 batches of nine Ophiocordyceps species and its allies in China..

Energy & fatigueSkin & hydration

High relevance

Shiitake · 2017 · Research Article · Genes

Development of 44 Novel Polymorphic SSR Markers for Determination of Shiitake Mushroom (Lentinula edodes) Cultivars.

The shiitake mushroom (Lentinulaedodes) is one of the most popular edible mushrooms in the world and has attracted attention for its value in medicinal and pharmacological uses..

High relevance

Cordyceps · 2017 · Research Article · Mycobiology

Development of High Cordycepin-Producing Cordyceps militaris Strains.

Cordyceps militaris, known as Dong-Chong-Xia-Cao, produces the most cordycepin among Cordyceps species and can be cultured artificially. For these reasons, C.

High relevance

Cordyceps · 2017 · Journal Article · Journal of food composition and analysis

Effect of light-emitting diodes on the production of cordycepin, mannitol and adenosine in solid-state fermented rice by Cordyceps militaris

The effects of different light-emitting diode (LED) conditions including different LED wavelengths and LED wavelength combinations on the production of bioactive compounds of Cordyceps militaris cultivated on brown rice were investigated..

High relevance

King Oyster · 2017 · Journal Article · Biochemical and Biophysical Research Communications

Effect of oxidation of the non-catalytic β-propeller domain on the substrate specificity of prolyl oligopeptidase from Pleurotus eryngii

Enzymes belonging to the S9 family of prolyl oligopeptidases are of interest because of their pharmacological importance and have a non-catalytic β-propeller domain..

High relevance

King Oyster · 2017 · Journal Article · Biochemical and biophysical research communications

Effect of oxidation of the non-catalytic β-propeller domain on the substrate specificity of prolyl oligopeptidase from Pleurotus eryngii.

Enzymes belonging to the S9 family of prolyl oligopeptidases are of interest because of their pharmacological importance and have a non-catalytic β-propeller domain..

High relevance

Cordyceps · 2017 · Journal Article · International journal of medicinal mushrooms

Effect of Pulsed Light Irradiation on Bioactive, Nonvolatile Components and Antioxidant Properties of Caterpillar Medicinal Mushroom Cordyceps militaris (Ascomycetes).

The caterpillar medicinal mushroom Cordyceps militaris contains many bioactive components, such as adenosine, cordycepin, and polysaccharides. In this study, C.

Immune support

High relevance

Niu-Chang-Chih · 2017 · Journal Article · Journal of ethnopharmacology

Effects of antrosterol from Antrodia camphorata submerged whole broth on lipid homeostasis, antioxidation, alcohol clearance, and anti-inflammation in livers of chronic-alcohol fed mice.

ETHNOPHARMACOLOGICAL RELEVANCE: Antrodia camphorata is a functional fungus in Taiwan and owns several pharmacological functions. Antrosterol, a bioactive constitute of sterols in edible Antrodia camphorata submerged whole broth, can protect liver from CCl4 damage via enhancing antioxidant and anti-inflammatory….

Immune supportMetabolic healthLiver support

High relevance

Reishi · 2017 · Journal Article · International journal of medicinal mushrooms

Effects of Exogenous Salicylic Acid on Ganoderic Acid Biosynthesis and the Expression of Key Genes in the Ganoderic Acid Biosynthesis Pathway in the Lingzhi or Reishi Medicinal Mushroom, Ganoderma lucidum (Agaricomycetes).

We demonstrate herein that salicylic acid (SA) can enhance ganoderic acid (GA) accumulation in the lingzhi or reishi medicinal mushroom Ganoderma lucidum. Following treatment with different concentrations of SA, the GA content was increased 22.72% to 43.04% compared with the control group..

Metabolic health

High relevance

Shiitake · 2017 · Journal Article · European journal of nutrition

Effects of Lentinula edodes consumption on biochemical, hematologic and oxidative stress parameters in rats receiving high-fat diet.

PURPOSE: Functional foods can prevent/reduce the risks related to obesity. Lentinula edodes is a highly nutritious mushroom rich in protein, vitamins and minerals.

Metabolic healthLiver support

High relevance

King Oyster · 2017 · Research Article · International journal of molecular sciences

Ergostane-Type Sterols from King Trumpet Mushroom (Pleurotus eryngii) and Their Inhibitory Effects on Aromatase.

Two new ergostane-type sterols; (22E)-5α,6α-epoxyergosta-8,14,22-triene-3β,7β-diol (1) and 5α,6α-epoxyergost-8(14)-ene-3β,7α-diol (2) were isolated from the fruiting bodies of king trumpet mushroom (Pleurotus eryngii), along with eight known compounds (3-10)..

High relevance

Cordyceps · 2017 · Journal Article · Journal of the science of food and agriculture

Evaluation of different agricultural wastes for the production of fruiting bodies and bioactive compounds by medicinal mushroom Cordyceps militaris

BACKGROUND: In commercial production of Cordyceps militaris (a famous Chinese medicine), cereal grains are usually utilized as cultivation substrates. This study aimed to evaluate the efficiency of agricultural wastes as substitute materials in the low‐cost production of C.

Immune support

High relevance

Cordyceps · 2017 · Journal Article · Applied biochemistry and biotechnology

Functional Analysis of Ribonucleotide Reductase from Cordyceps militaris Expressed in Escherichia coli.

Cordyceps militaris produces cordycepin (3'-deoxyadenosine), which has various activities, including anti-oxidant, anti-tumoral, anti-viral, and anti-inflammatory. Ribonucleotide reductase (RNR) seems to be a candidate to produce cordycepin in C..

OncologyImmune supportMetabolic healthRespiratory

High relevance

Reishi · 2017 · Journal Article · Biochemical and biophysical research communications

Ganoderma lucidum (Reishi) suppresses proliferation and migration of breast cancer cells via inhibiting Wnt/β-catenin signaling.

The medical mushroom Ganoderma lucidum (Reishi), a traditional Chinese medicine, has exhibited a promising anti-cancer effect. However, the molecular mechanism of its action on cancer cells remains unclear..

Oncology

High relevance

Cordyceps · 2017 · Journal Article · Gene

Genome-scale metabolic network of Cordyceps militaris useful for comparative analysis of entomopathogenic fungi.

The first genome-scale metabolic network of Cordyceps militaris (iWV1170) was constructed representing its whole metabolisms, which consisted of 894 metabolites and 1,267 metabolic reactions across five compartments, including the plasma membrane, cytoplasm, mitochondria, peroxisome and extracellular space..

Energy & fatigueMetabolic health

High relevance

Maitake · 2017 · Research Article · International journal of molecular medicine

Grifola frondosa polysaccharides induce breast cancer cell apoptosis via the mitochondrial-dependent apoptotic pathway.

Grifola frondosa, a type of food and medical fungus, has been shown to exhibit various pharmacological activities, including anticancer effects. As the most typical cancer diagnosed among female patients, breast cancer remains a huge concern threatening human health globally..

OncologyImmune supportEnergy & fatigue

High relevance

King Oyster · 2017 · Journal Article · Carbohydrate polymers

Hepatoprotection of enzymatic-extractable mycelia zinc polysaccharides by Pleurotus eryngii var. tuoliensis.

The purpose of this work was designed to investigate the hepatoprotective and antioxidant effects of enzymatic-extractable mycelia zinc polysaccharides (En-MZPS) from Pleurotus eryngii var. tuoliensis on the hyperlipidemic mice induced by high-fat-high-cholesterol emulsion (HFHCM)..

Immune supportMetabolic healthLiver support

High relevance

Shiitake · 2017 · Journal Article · Bioscience, biotechnology, and biochemistry

Heterologous expression of the Pleurotus ostreatus MnP3 gene by the laccase gene promoter in Lentinula edodes.

Lentinula edodes (shiitake), which have a powerful ligninolytic system, is one of the most important edible mushrooms in Asia. In this study, we introduced the manganese peroxidase (MnP, EC 1.11.1.13) gene from Pleurotus ostreatus driven by L.

High relevance

Cordyceps · 2017 · Research Article · Marine drugs

Higher Anti-Liver Fibrosis Effect of Cordyceps militaris-Fermented Product Cultured with Deep Ocean Water via Inhibiting Proinflammatory Factors and Fibrosis-Related Factors Expressions.

Deep ocean water (DOW) has been shown to enhance the functional components of fungi, resulting in increased health benefits. Therefore, using DOW for culturing fungi can enhance the cordycepin and adenosine of Cordyceps militaris (CM) and its protective effects on the liver..

Immune supportEnergy & fatigueLiver supportSkin & hydration

High relevance

Cordyceps · 2017 · Journal Article · Journal of chromatography. B, Analytical technologies in the biomedical and life sciences

Identification of a novel component leading to anti-tumor activity besides the major ingredient cordycepin in Cordyceps militaris extract.

In accordance with our previous study that was carried out to identify novel anti-tumor ingredients, chromatographic separation in combination with an anti-tumor activity assay was used for analysis of Cordyceps militaris extract in this study..

Oncology

High relevance

King Oyster · 2017 · Journal Article · International journal of medicinal mushrooms

Immunomodulatory Effects of Extracellular β-Glucan Isolated from the King Oyster Mushroom Pleurotus eryngii (Agaricomycetes) and Its Sulfated Form on Signaling Molecules Involved in Innate Immunity.

The aim of this study was to determine, using murine RAW 264.7 macrophages, the immunomodulatory effect of extracellular β-glucan isolated from Pleurotus eryngii (PEBG) and its sulfated derivative (PEBG-S) on signaling molecules implicated in host innate immunity..

OncologyImmune supportEnergy & fatigue

High relevance

King Oyster · 2017 · Journal Article · Food & function

In vitro and in vivo inhibitory effects of a Pleurotus eryngii protein on colon cancer cells.

Edible mushrooms have been considered as a good source of bioactive components with various health benefits. Our previous study demonstrated the identity of a novel protein from Pleurotus eryngii, namely PEP, and its anti-inflammatory activities..

OncologyImmune supportGut & microbiome

High relevance

King Oyster · 2017 · Journal Article · International journal of medicinal mushrooms

In Vitro Antioxidant and In Vivo Hypolipidemic Effects of the King Oyster Culinary-Medicinal Mushroom, Pleurotus eryngii var. ferulae DDL01 (Agaricomycetes), in Rats with High-Fat Diet-Induced Fatty Liver and Hyperlipidemia.

We investigated the effect of the culinary-medicinal mushroom Pleurotus eryngii var. ferulae DDL01 on oxidative damage in the liver and brain and a high-fat/high-cholesterol-induced hyperlipidemic model..

Cognition & nervesMetabolic healthLiver support

High relevance

King Oyster · 2017 · Journal Article · Food & function

In vivo fermentation of a Pleurotus eryngii polysaccharide and its effects on fecal microbiota composition and immune response.

A novel, homogeneous Pleurotus eryngii polysaccharide (PEP) (molecular weight 426 kDa, purity 91.25 ± 3.14%) which mainly consisted of glucose with β-type glycosidic linkages was used to investigate in vivo fermentation behavior and effects on immune response in mice..

Immune supportMetabolic healthGut & microbiome

High relevance

Cordyceps · 2017 · Research Article · Nutrition research and practice

Increased glucose metabolism and alpha-glucosidase inhibition in Cordyceps militaris water extract-treated HepG2 cells.

BACKGROUND/OBJECTIVES: Recent living condition improvements, changes in dietary habits, and reductions in physical activity are contributing to an increase in metabolic syndrome symptoms including diabetes and obesity..

Metabolic healthLiver support

High relevance

King Oyster · 2017 · Journal Article · Food & function

Isolation of a novel bioactive protein from an edible mushroom Pleurotus eryngii and its anti-inflammatory potential.

Edible mushrooms are rich sources of bioactive components. In this study, a bioactive protein, PEP, was isolated from an edible mushroom, Pleurotus eryngii, through (NH4)2SO4 precipitation and ion-exchange chromatography..

Immune supportGut & microbiome

High relevance

Maitake · 2017 · Journal Article · Carbohydrate polymers

Isolation, purification, structural analysis and immunostimulatory activity of water-soluble polysaccharides from Grifola Frondosa fruiting body.

A new polysaccharide had been successfully isolated from maitake mushroom (Grifola Frondosa)-GFP. HPLC and Monosaccharide analysis showed that the average molecular weight of GFP was 155kDa and it was mainly composed of rhamnose, xylose, mannose, glucose, molar ratio of 1.00: 1.04: 1.11: 6.21..

Immune supportMetabolic health

High relevance

Enoki · 2017 · Journal Article · Journal of proteomics

iTRAQ-based quantitative proteome revealed metabolic changes of Flammulina velutipes mycelia in response to cold stress.

UNLABELLED: Temperature is one of the pivotal factors influencing mycelium growth and fruit-body formation of Flammulina velutipes. To gain insights into hyphae growth and fruit-body formation events and facilitate the identification of potential stage-specific biomarker candidates, we investigated the proteome….

Metabolic health

High relevance

Shiitake · 2017 · Research Article · Applied and environmental microbiology

Lentinula edodes Genome Survey and Postharvest Transcriptome Analysis.

Lentinula edodes is a popular, cultivated edible and medicinal mushroom. Lentinula edodes is susceptible to postharvest problems, such as gill browning, fruiting body softening, and lentinan degradation..

High relevance

Lion's Mane · 2017 · Journal Article · International journal of medicinal mushrooms

Lion's Mane Medicinal Mushroom, Hericium erinaceus (Agaricomycetes), Modulates Purinoceptor-Coupled Calcium Signaling and Murine Nociceptive Behavior.

Hericium erinaceus is well known for the neurotrophic effect it confers by promoting nerve growth factor biosynthesis. We discovered a novel bioactivity of H.

Cognition & nervesLiver support

High relevance

Cordyceps · 2017 · Research Article · Laboratory animal research

Lipolytic effect of novel extracts from mulberry (Morus alba) leaves fermented with Cordyceps militaris in the primary adipocytes derived from SD rats.

Mulberry (Morus alba) leaves are known to have therapeutic effects on lipid metabolism including lipogenesis, lipolysis and hyperlipidemia. However, novel compounds with strong lipolytic ability among 27 extracts of the mulberry leaves fermented with Cordyceps militaris (EMfCs) have not yet been identified..

Metabolic health

High relevance

Cordyceps · 2017 · Journal Article · Archives of microbiology

Molecular analysis and biochemical characteristics of degenerated strains of Cordyceps militaris.

Cordyceps militaris has commercially been cultivated, but its degenerated subcultures have gradually resulted in the reduced production. In this study, the biological characteristics and DNA change of degenerated strains of C.

Metabolic health

High relevance

Shiitake · 2017 · Journal Article · Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes

Multi-elemental analysis of Lentinula edodes mushrooms available in trade.

The present study investigated the content of 62 elements in the fruiting bodies of Lentinula edodes (Shiitake mushroom) cultivated commercially in Poland on various substrates from 2007-2015..

High relevance

King Oyster · 2017 · Research Article · International journal of molecular sciences

Olive Mill Waste Enhances α-Glucan Content in the Edible Mushroom Pleurotus eryngii.

Mushroom polysaccharides are edible polymers that have numerous reported biological functions; the most common effects are attributed to β-glucans. In recent years, it became apparent that the less abundant α-glucans also possess potent effects in various health conditions..

Immune support

High relevance

Cordyceps · 2017 · Journal Article · International journal of medicinal mushrooms

Photoperiodic Responses and Characterization of the Cmvvd Gene Encoding a Blue Light Photoreceptor from the Medicinal Caterpillar Fungus Cordyceps militaris (Ascomycetes).

Light is a necessary environmental factor for production of conidia and pigment, formation of stroma, and development of Cordyceps militaris, a well-known edible and medicinal mushroom. In this study, an obvious rhythm loop was observed in certain strains of C..

Cognition & nervesEnergy & fatigue

High relevance

King Oyster · 2017 · Journal Article · The Journal of organic chemistry

Pleurocins A and B: Unusual 11(9 → 7)-abeo-Ergostanes and Eringiacetal B: A 13,14-seco-13,14-Epoxyergostane from Fruiting Bodies of Pleurotus eryngii and Their Inhibitory Effects on Nitric Oxide Production.

Two novel 11(9 → 7)-abeo-ergostane-type steroids, named pleurocins A (1) and B (2), a 13,14-seco-13,14-epoxy ergostane, named eringiacetal B (3), and an ergostane steroid (4) were isolated from the fruiting bodies of Pleurotus eryngii (Pleurotaceae)..

Oncology

High relevance

King Oyster · 2017 · Journal Article · Journal of food processing and preservation

Preparation and Antioxidant Activities of Oligosaccharides Derived from Pleurotus eryngii Polysaccharides

Pleurotus eryngii oligosaccharides (PEOs) were prepared by hydrolyzing P. eryngii polysaccharides with hydrogen peroxide (H₂O₂).

Immune support

High relevance

Maitake · 2017 · Research Article · Iranian journal of pharmaceutical research: IJPR

Purification, Characterization and Antioxidant Activities of Enzymolysis Polysaccharide from Grifola frondosa.

Our previous study revealed that the antioxidant activity of polysaccharide (coded as FGFP) extracted from Grifola frondosa by enzymolysis treatment was significantly superior than that (coded as GFP) extracted by boiling-water..

Immune supportMetabolic health

High relevance

King Oyster · 2017 · Journal Article · Protein engineering, design & selection: PEDS

Rational design of Pleurotus eryngii versatile ligninolytic peroxidase for enhanced pH and thermal stability through structure-based protein engineering.

Versatile peroxidase (VP) from Pleurotus eryngii is a high redox potential peroxidase. It has aroused great biotechnological interest due to its ability to oxidize a wide range of substrates, but its application is still limited due to low pH and thermal stability..

High relevance

Almond Mushroom · 2017 · Journal Article · Food & function

Regulation of RAW 264.7 cell-mediated immunity by polysaccharides from Agaricus blazei Murill via the MAPK signal transduction pathway.

Agaricus blazei Murill (ABM) is a common anticancer folk remedy. Its active ingredients, i.e., polysaccharides, have been isolated and exhibit indirect tumor-suppressing activity via immunological activation.

OncologyImmune support

High relevance

King Oyster · 2017 · Journal Article · Carbohydrate polymers

Safe therapeutics of murine melanoma model using a novel antineoplasic, the partially methylated mannogalactan from Pleurotus eryngii.

A heteropolysaccharide was isolated by cold aqueous extraction from edible mushroom Pleurotus eryngii ("King Oyster") basidiocarps and its biological properties were evaluated. Structural assignments were carried out using mono- and bidimensional NMR spectroscopy, monosaccharide composition, and methylation analyses..

OncologyImmune supportMetabolic health

High relevance

Shiitake · 2017 · Journal Article · International journal of food science & technology

Secondary metabolism associated with softening of shiitake mushroom (Lentinula edodes) induced by O2 depletion and CO2 accumulation

It is difficult to preserve fresh shiitake mushroom (Lentinula edodes (Berk.) sing) partly because of the rapid deterioration of texture (softening or lignification)..

Immune support

High relevance

Cordyceps · 2017 · Journal Article · Cereal chemistry

Solid‐State Bioprocessing with Cordyceps militaris Enhanced Antioxidant Activity and DNA Damage Protection of Red Beans (Phaseolus angularis)

In this study, red beans were bioprocessed by using a novel solid‐state fermentation (SSF) with an edible and medical filamentous fungus Cordyceps militaris. The effect of SSF on the total phenolic content (TPC), antioxidant activity, and DNA damage protection of red beans was determined..

High relevance

Cordyceps · 2017 · Research Article · Molecules (Basel, Switzerland)

Stable Carbon Isotope Composition of the Lipids in Natural Ophiocordyceps sinensis from Major Habitats in China and Its Substitutes.

Ophiocordyceps sinensis is one rare medicinal fungus produced in the Qinghai-Tibetan Plateau. Its quality and price varies hugely with different habitat, and its numerous substitutes have sprung up in functional food markets.

High relevance

Maitake · 2017 · Journal Article · Carbohydrate polymers

Structural elucidation and antioxidant activity a novel Se-polysaccharide from Se-enriched Grifola frondosa.

Se-GFP-22, a heteropolysaccharide, with a weight-average Mw of 4.13×106Da, was purified from the crude Se-polysaccharide (Se-GFP) isolated from fruit bodies of Se-enriched Grifola frondosa. Selenium was accumulated efficiently in Grifola frondosa during cultivation with Na2SeO3..

Immune support

High relevance

Cordyceps · 2017 · Journal Article · Carbohydrate polymers

Structural elucidation and immunostimulatory activity of polysaccharide isolated by subcritical water extraction from Cordyceps militaris.

Water-soluble polysaccharides were obtained from Cordyceps militaris (C. militaris) (CMP) by subcritical water extraction (SWE).

Immune supportMetabolic health