MycoData

Three gamma-glutamyltranspeptidase (enzymes I, II and III) were partially purified from the cell free extracts of the cultured mycelia of Morchella esculenta Fr. The molecular masses of enzymes were 155,000 (I), 219,000 (II) and 102,000 (III)..

Medium relevance

Maitake · 1985 · Journal Article · Journal of pharmacobio-dynamics

Effect of a polysaccharide fraction from Grifola frondosa on immune response in mice.

The biological and immunomodulating activities of polysaccharide fraction (GF-1), an antitumor poysaccharide fraction from cultured fruiting bodies of Grifola frondosa, was examined in mice. GF-1 showed no cytocidal effect on culturing tumor cells..

OncologyImmune support

Medium relevance

Snow Fungus · 1985 · Journal Article · Agricultural and biological chemistry

Synthesis of a model linear mannohexaose for the backbone structure of fruit body polysaccharide of Tremella fuciformis and Dictyophora indusiata Fisch.

Synthesis of linear D-manno-oligosaccharides, O-α-D-Man-{(1→3)-O-α-D-Man}n-(1→3)-O-α-D-Man (n=0&sim;4), which correspond to part of the structure of the cell-wall polysaccharide of Tremella fuciformis and Dictyophora indusiata FISCH, is described..

Immune support

Medium relevance

Maitake · 1984 · Journal Article · Journal of pharmacobio-dynamics

Antitumor activity of a polysaccharide fraction extracted from cultured fruiting bodies of Grifola frondosa.

Antitumor activity of a polysaccharide fraction (GF-1) extracted from cultured fruiting bodies of a fungus, Grifola frondosa, was examined on allogeneic and syngeneic tumors in mice..

OncologyImmune support

Medium relevance

Enoki · 1983 · Journal Article · Journal of pharmacobio-dynamics

AUGMENTATION OF HOST'S IMMUNITY BY COMBINED CRYODESTRUCTION OF SARCOMA 180 AND ADMINISTRATION OF PROTEIN-BOUND POLYSACCHARIDE, EA6, ISOLATED FROM FLAMMULINA VELUTIPES (CURT.ex FR.) SING.IN ICR MICE

Augmentation of the host's immunity by combined in situ freeze-destruction of the tumor (cryosurgery) and administration of the antitumor active protein-bound polysaccharide, EA6, isolated from a hot water extract of an edible mushroom, Flammulina velutipes (Curt..

OncologyImmune support

Medium relevance

Enoki · 1983 · Journal Article · Journal of pharmacobio-dynamics

INTENSIFICATION OF ANTITUMOR-IMMUNITY BY PROTEINBOUND POLYSACCHARIDE, EA6, DERIVED FROM FLAMMULINA VELUTIPES (CURT.ex FR.) SING. COMBINED WITH MURINE LEUKEMIA L1210 VACCINE IN ANIMAL EXPERIMENTS

The antitumor effect of protein-bound polysaccharide, EA6, derived from fruit bodies of Flammulina velutipes (Curt. ex Fr.) Sing., when combined with a vaccine treatment was studied by the challenge test in BDF1 mice and L1210 murine leukemia system..

OncologyImmune support

Medium relevance

Enoki · 1982 · Journal Article · Journal of pharmacobio-dynamics

AUGMENTATION OF ANTITUMOR ACTIVITY BY COMBINED CRYODESTRUCTION OF SARCOMA 180 AND PROTEIN-BOUND POLYSACCHARIDE, EA6, ISOLATED FROM FLAMMULINA VELUTIPES (CURT. EX FR.) SING. IN ICR MICE

Augmentation of antitumor activity by combined in situ freeze-destruction of tumor (cryosurgery) and administration of antitumor active substances isolated from a hot water extract of an edible mushroom, Flammulina velutipes (Curt. ex Fr.) SING., was investigated in sarcoma 180 bearing ICR mice..

OncologyImmune support

Medium relevance

Cordyceps · 2026 · Research Article · Pharmaceutics

A Green Self-Assembled Nanoplatform of 10-Hydroxycamptothecin and Cordyceps Polysaccharides for Dual Anti-Tumor Efficacy Through Apoptosis and Immune Modulation.

Background: Melanoma is one of the most dangerous types of skin cancer, with its global incidence having surged in recent years. There exists an urgent clinical need for novel therapeutic strategies that combine high efficacy, low toxicity, and multiple mechanisms of action..

OncologyImmune supportLiver supportSkin & hydration

Medium relevance

Cordyceps · 2026 · Journal Article · Industrial crops and products

An active polysaccharide isolated from cultivated Cordyceps Chanhua: Structural elucidation and anti-inflammatory/antioxidant effects on human intestinal Caco-2 cells

Artificially cultivated Cordyceps chanhua is commonly used in medicinal and edible applications, with polysaccharides serve as the primary bioactive compounds and critical indicators for quality control..

Immune supportMetabolic healthGut & microbiome

Medium relevance

Shiitake · 2026 · Research Article · Foods (Basel, Switzerland)

Atmospheric Cold Plasma Degradation of Fenvalerate Residues on Shiitake Mushrooms: Mechanisms, Toxicity Evolution, and Quality Effects.

Fenvalerate residues on edible mushrooms pose significant risks to food safety and aquatic ecosystems. This study investigated the efficiency, degradation mechanisms, toxicity evolution, and quality effects of atmospheric cold plasma (ACP) for removing fenvalerate from shiitake mushrooms..

Energy & fatigue

Medium relevance

Cordyceps · 2026 · Journal Article · Phytotherapy research: PTR

Bioactive Sphingolipids of Cordyceps sinensis Modulate Tumor Immunity Through the SphK1-Mediated Cer/S1P Axis.

Cordyceps sinensis is a traditional medicinal fungus known for its immunomodulatory properties. Its bioactive sphingolipids (SPLs) exhibit antitumor potential, though their mechanisms remain poorly understood.

OncologyImmune supportRespiratory

Medium relevance

Cordyceps · 2026 · Journal Article · Pest management science

Context-dependent compatibility of the entomopathogenic fungus Cordyceps javanica JS001 with the predatory bug Cyrtorhinus lividipennis suggests potential for enhancing suppression of the rice planthopper Nilaparvata lugens.

BACKGROUND: The brown planthopper, Nilaparvata lugens, is a devastating rice pest in Asia. Although both the entomopathogenic fungus Cordyceps javanica JS001 and the predatory mirid bug Cyrtorhinus lividipennis are promising biocontrol agents, their compatibility remains unassessed..

Medium relevance

Cordyceps · 2026 · Research Article · Scientific reports

Cordyceps sinensis enhances the efficacy of anti-PD-1 immunotherapy in Lewis lung adenocarcinoma.

Lung cancer, primarily non-small cell lung cancer (NSCLC), causes the highest cancer-related mortality. Although PD-1/PD-L1 inhibitors have improved survival in advanced NSCLC, they can cause immune-related adverse events.

OncologyImmune supportMetabolic healthRespiratory

Medium relevance

Cordyceps · 2026 · Research Article · Experimental & applied acarology

Corn oil-formulated Cordyceps javanica: a high-performance, low-impact tool for integrated tick management.

Mycoacaricides represent a promising alternative for managing resistant tick populations. This study evaluated the efficacy of corn oil-based Cordyceps javanica formulations against non-parasitic stages the southern cattle tick Rhipicephalus microplus under laboratory and semi-field conditions..

Energy & fatigue

Medium relevance

Shiitake · 2026 · Journal Article · International journal of biological macromolecules

Development of pH-sensitive colorimetric labels base on chitosan-agar films embedded with alizarin and cinnamaldehyde essential oil for monitoring the freshness of fresh-cut papayas and shiitake mushrooms.

The pH-sensitive colorimetric labels (PSCLs) were developed to monitor the freshness of fresh-cut papayas and shiitake mushrooms. These PSCLs were prepared using the solution-casting films and thoroughly characterized in terms of their physicochemical and thermal properties, microstructure, and application….

Energy & fatigue

Medium relevance

Cordyceps · 2026 · Journal Article · Journal of toxicology and environmental health. Part A

In vitro anti-inflammatory activity of ethyl acetate extract and nicotinic acid from Cordyceps neovolkiana DL0004 in RAW 264.7 macrophages.

The aim of this study was to investigate the anti-inflammatory properties of the ethyl acetate extract (EA) of Cordyceps neovolkiana DL0004, a native fungal species recently isolated in Vietnam and its purified compound, nicotinic acid (NCA), using in vitro assays..

OncologyImmune support

Medium relevance

Cordyceps · 2026 · Journal Article · Journal of hazardous materials

Innovative insights into hexavalent chromium [Cr(VI)] removal by Cordyceps chanhua: Integrating physicochemical characterization and molecular functional analysis.

Hexavalent chromium [Cr(VI)] contamination poses significant environmental and health challenges, yet the molecular basis of fungal-mediated Cr(VI) detoxification remains insufficiently understood..

Medium relevance

Oyster Mushroom · 2026 · Journal Article · Current biology: CB

Invasion biology: The golden oyster mushroom in North America.

The golden oyster mushroom, Pleurotus citrinopileatus, is native to Asia and is rapidly expanding across North America. Two recent studies describe the genetic diversity of naturalized populations of P.

Medium relevance

Cordyceps · 2026 · Journal Article · Crop protection

Morphological and multilocus identification of a Philippine indigenous Cordyceps javanica (Hypocreales: Cordycipitaceae) and its biocontrol potential against the kanzawa spider mite Tetranychus kanzawai Kishida (1927) (Acari: Tetranychidae)

Cordyceps javanica (Frieder. & Bally) Kepler et al.

Gut & microbiome

Medium relevance

Cordyceps · 2026 · Research Article · Biomolecules

New Pyridinone Alkaloid and Polyketide from the Cordyceps-Colonizing Fungus Pseudogymnoascus roseus.

One new pyridinone alkaloid pseudogymnone A (1) and one new tricyclic polyketide penijanthinone C (2), together with six known compounds, harzianic acid (3), 3-methyl-2-(2-nonenyl)-4(1H)-quinolinone (4), emodic acid (5), alaternin (6), violaceol-I (7), and violaceol-II (8), were obtained from the Cordyceps-colonizing….

OncologyGut & microbiome

Medium relevance

Reishi · 2026 · Journal Article · Natural product research

Physicochemical profiles and antioxidant capacities of lingzhi (Ganoderma lingzhi) polysaccharides under different extraction regimes.

Polysaccharides (GLPs) were extracted from the fruiting bodies of Ganoderma lingzhi using an optimised water-extraction and alcohol-precipitation method. Two homogeneous fractions (GLP1 and GLP2) were purified, and their molecular weights, monosaccharide compositions, and antioxidant activities were characterised via….

Immune supportEnergy & fatigueMetabolic health

Medium relevance

Cordyceps · 2026 · Research Article · Molecules (Basel, Switzerland)

Secondary Metabolites with Antithrombotic and Antioxidant Activities Derived from Cordyceps cicadae.

Cordyceps cicadae, a medicinal and edible entomopathogenic fungus, has been widely used in traditional Chinese medicine for treating various ailments. This study aimed to validate its ethnopharmacological uses by investigating bioactive constituents and their antithrombotic and antioxidant activities..

Medium relevance

Shiitake · 2026 · Journal Article · BMC biotechnology

Study on the mesoscopic characteristics of densified forming of shiitake mushroom residue biomass considering particle breakage.

The development of biomass pellet fuels represents an important pathway for achieving a low-carbon energy transition. Based on the particle breakage behavior of the feedstock, this study investigated the mesoscopic characteristics of the densification process of shiitake mushroom residue (SMR) biomass using piston….

Energy & fatigue

Medium relevance

Cordyceps · 2026 · Journal Article · Fungal genetics and biology: FG & B

Targeted deletion of cc63tf and cc12grf reveals opposing regulation of beauvericin biosynthesis in Cordyceps cicadae.

Cordyceps cicadae (C. cicadae), a species widely used in traditional Chinese medicine, belongs to the family Cordycepsaceae (order Hypocreales, class Ascomycota).

Metabolic health

Medium relevance

Cordyceps · 2026 · Journal Article · Fungal biology

The CcSO gene plays a critical role in the development of asexual fruiting bodies in Cordyceps cicadae.

Cordyceps cicadae is a rare and valuable traditional edible-medicinal fungus. Its asexual fruiting bodies exhibit significant pharmacological properties.

Cognition & nerves

Medium relevance

Cordyceps · 2026 · Research Article · Genes

Transcriptomic Insights into the Molecular Responses of Red Imported Fire Ants (Solenopsis invicta) to Beta-Cypermethrin and Cordyceps cicadae.

BACKGROUND: Solenopsis invicta, commonly known as the red imported fire ant (RIFA), is an important global invasive pest, and its management is challenging because of insecticide resistance and environmental problems. METHODS: In this research, we applied transcriptomics to analyze the molecular responses of S..

Immune supportCognition & nervesMetabolic health

Medium relevance

Cordyceps · 2026 · Journal Article · Natural product research

Two new polyketide-amino acid hybrids with antibacterial activities from Cordyceps cicadae.

Cordyceps cicadae (Chanhua in Chinese), a species recognised for its medicinal properties and used as one traditional Chinese medicine (TCM), has been extensively studied for its bioactive components. In this study, two new polyketide-amino acid hybrids were isolated and characterised from C.

Medium relevance

Oyster Mushroom · 2025 · Research Article · Foods (Basel, Switzerland)

(1→3)-α-d-Glucan from the Pink Oyster Mushroom (Pleurotus djamor): Structural Features.

(1→3)-α-d-Glucan is an important component of the cell wall of most fungi. The polymer has many applications, including as a therapeutic agent in the prevention or treatment of various diseases, as well as a heavy metal sorbent and a component of new materials used in the plastics industry..

Immune supportMetabolic health

Medium relevance

Cordyceps · 2025 · Journal Article · Natural product research

A new sesterterpenoid with β-glucuronidase inhibitory activity from the Cordyceps-colonising fungus Aspergillus versicolour ZJUTE2.

A new sesterterpenoid versicolorin A (1) and five known compounds 2-6 were isolated from a Cordyceps-colonising fungus Aspergillus versicolour ZJUTE2 cultured on soybean meal. The planar structure of 1 was determined by 1D, 2D NMR and HR-ESI-MS..

Gut & microbiome

Medium relevance

Nameko · 2025 · Journal Article · Natural product research

A novel polysaccharide from Pholiota nameko (T. Itô) S. Ito & S. Imai residue: chemical structure and hypoglycaemic activity in vitro.

A novel polysaccharide (APNP) with a molecular weight of 3.56 × 103 KDa and a total sugar content of 92.35 ± 0.07% was isolated from Pholiota nameko (T. Itô) S.

Immune supportMetabolic health

Medium relevance

Cordyceps · 2025 · Research Article · Sensors (Basel, Switzerland)

A Progressive Feature Learning Network for Cordyceps sinensis Image Recognition.

Cordyceps sinensis (C. sinensis) is a valuable herbal medicine with wide-ranging applications.

Cognition & nerves

Medium relevance

Cordyceps · 2025 · Research Article · Antioxidants (Basel, Switzerland)

An Antioxidative Exopolysaccharide-Protein Complex of Cordyceps Cs-HK1 Fungus and Its Epithelial Barrier-Protective Effects in Caco-2 Cell Culture.

The exopolysaccharides (EPS) from the mycelial fermentation of Cordyceps sinensis Cs-HK1, especially the low-molecular weight, protein-rich exopolysaccharide fractions (EPS-LM), have previously exhibited significant antioxidant activity..

Immune supportGut & microbiome

Medium relevance

Turkey Tail · 2025 · Journal Article · Journal of functional foods

Anti-inflammatory and immunomodulatory effects in vitro of polysaccharide- and polyphenol-rich extracts of white button and Turkey Tail mushrooms

The health-promoting properties of mushrooms are associated with bioactive natural compounds such as polysaccharides and polyphenols. Anti-inflammatory and immunomodulatory properties of edible white button mushroom (WBM) and medicinal Turkey Tail mushroom (TT) were investigated..

Immune supportLiver support

Medium relevance

Lion's Mane · 2025 · Research Article · Foods (Basel, Switzerland)

Application Potential of Lion's Mane Mushroom in Soy-Based Meat Analogues by High Moisture Extrusion: Physicochemical, Structural and Flavor Characteristics.

The aim of this work was to systematically evaluate the effects of Lion's Mane Mushroom powder (LMM, 0-40%) on the physicochemical properties, structural characteristics, and flavor profile of soy protein isolate-based high-moisture meat analogues (HMMAs)..

Immune supportSkin & hydration

Medium relevance

Cordyceps · 2025 · Journal Article · Journal of economic entomology

Assessment of the pathogenicity of oil-based formulation of Cordyceps fumosorosea combined with thiamethoxam against Diaphorina citri.

Mycopesticides are crucial for integrated management of the Asian citrus psyllid (ACP, Diaphorina Citri), yet highly virulent formulations remain inadequately studied..

Medium relevance

Cordyceps · 2025 · Journal Article · Journal of invertebrate pathology

Chitin-amended media: Improving efficacy of Cordyceps fumosorosea as a control agent of Cydia pomonella.

The microbial control of insect pests such as the codling moth Cydia pomonella is a major challenge in the apple industry. This study investigates the potential of chitin-amended media to improve the efficacy of the entomopathogenic fungus Cordyceps fumosorosea strain JKI-BI-1496 for control of C.

Medium relevance

Cordyceps · 2025 · Research Article · Journal of fungi (Basel, Switzerland)

Co-Culture with Two Soil Fungal Strains Enhances Growth and Secondary Metabolite Biosynthesis in Cordyceps takaomontana.

Cordyceps takaomontana is a medicinal fungus with significant pharmacological value, but how soil microbes promote its growth remains unclear. We established a solid-state co-culture system involving C.

Metabolic healthGut & microbiome

Medium relevance

Cordyceps · 2025 · Journal Article · Journal of medicinal food

Cordyceps cicadae Extracts Exert Antiaging Effects by Activating the AMPK/SIRT1 Pathway in d-Galactose-Induced Aging Rats.

Cordyceps cicadae, a valuable traditional edible and medicinal resource, is recognized for its potential in slowing aging but has not been effectively exploited. This study aimed to explore antiaging activity and mechanisms of C.

Cognition & nerves

Medium relevance

Shiitake · 2025 · Journal Article · International journal of biological macromolecules

Development of a multifunctional and sustainable pterostilbene nanoemulsion incorporated chitosan-alginate food packaging film for shiitake mushroom preservation.

The pervasive use of petroleum-based food packaging has caused significant ecological damage due to their unsustainability and non-biodegradability. Polysaccharide-based biodegradable materials are promising alternatives, but low hydrophobicity and functional properties limit their practical applications which can be….

Immune supportEnergy & fatigue

Medium relevance

Cordyceps · 2025 · Research Article · Metabolites

Effects of Cordyceps cicadae Polysaccharide on Gut Microbiota, the Intestinal Mucosal Barrier, and Inflammation in Diabetic Mice.

Background: Polysaccharides produced by the edible fungus Cordyceps cicadae can regulate blood sugar levels and may represent a suitable candidate for the treatment of diabetes and its complications. However, there is limited information available about the mechanism of how C..

Immune supportMetabolic healthGut & microbiome

Medium relevance

Cordyceps · 2025 · Journal Article · Biological control

Efficacy of horizontal transmission of Cordyceps javanica in managing Drosophila suzukii populations

Drosophila suzukii (Matsumura) is a globally distributed pest of soft fruit crops with significant economic impact. This study evaluated the horizontal transmission of conidia of the entomopathogen, Cordyceps javanica, among D.

Medium relevance

Cordyceps · 2025 · Journal Article · Crop protection

Endophytic colonization via Cordyceps cateniannulata induces a growth-enhancing effect and increases the resistance of tomato plants against Tetranychus urticae (Koch)

Tetranychus urticae represents an important global agricultural pest capable of inflicting severe damage on numerous fruits, vegetables, and ornamental plants. Cordyceps cateniannulata is traditionally used for direct arthropod control, but its role as an endophyte for indirect pest management is underexplored..

Gut & microbiome

Medium relevance

Cordyceps · 2025 · Journal Article · Journal of food composition and analysis

Enzymatic characteristics and origin tracing of nucleotidase and adenosine deaminase in Cordyceps sinensis based on HPLC

Adenosine is a key quality marker for the valuable fungus Cordyceps sinensis (C. sinensis).

Medium relevance

Oyster Mushroom · 2025 · Research Article · Scientific reports

Exploring natural AMPK activators from bioactive compounds in fenugreek and oyster mushroom for management of type 2 diabetes.

Oral antidiabetic drugs mainly act by stimulating pancreatic β-cells, but prolonged stimulation may lead to exhaustion and impaired insulin secretion. In contrast, AMP-activated protein kinase (AMPK) lowers blood glucose through an insulin-independent pathway, offering therapeutic potential..

Metabolic health

Medium relevance

Lion's Mane · 2025 · Journal Article · Diseases of aquatic organisms

Gas bubble disease (supersaturation) in a population of lion's mane sea slugs Melibe leonina.

Two supersaturation events caused gas bubble disease (GBD) in captive Melibe leonina (lion's mane sea slugs). For the first event (a), supersaturation spikes (114-127% total dissolved gas [TDG]) occurred on Days 1a, 4a, and 23a.

Medium relevance

Cordyceps · 2025 · Research Article · International journal of molecular sciences

Genome Sequence, Comparative Genome Analysis, and Expression Profiling of the Chitinase GH18 Gene Family in Cordyceps javanica Bd01.

The fungus Cordyceps javanica is known for entomopathogenicity and effective in the control of various arthropods. Here, we aimed to reveal the chitinase GH18 gene family expansion through the high throughput sequencing of the genome of C.

Medium relevance

Oyster Mushroom · 2025 · Journal Article · Molecular neurobiology

Golden Oyster Mushroom Extract Ameliorates Oxidative Stress-Induced Cell Death in Neurons and Scopolamine-Induced Cholinergic System Impairment in Mice.

Impaired cholinergic system is an important therapeutic target to develop drugs against Alzheimer's disease (AD), as cholinergic signal transduction is associated with the memory, learning, and behavior of an individual..

Cognition & nerves

Medium relevance

Maitake · 2025 · Research Article · Journal of fungi (Basel, Switzerland)

Growth-Rate Related Quantitative Trait Locus Analysis of Monokaryotic Isolates of Grifola albicans f. huishuhua (Maitake).

A genetic linkage map of Grifola albicans f. huishuhua (Maitake) is an important resource for chromosome analysis and the genetic basis of phenotypic variation determination.

Medium relevance

Shiitake · 2025 · Journal Article · Journal of the science of food and agriculture

High‐intensity ultrasound treatment of shiitake mushroom protein isolate: effects on physicochemical, structural properties, and functional performance

BACKGROUND: With increasing consumer demand for healthy and sustainable food, plant proteins have been used widely in meat substitutes, dairy alternatives, and functional foods..

Energy & fatigue

Medium relevance

Cordyceps · 2025 · Research Article · Journal of fungi (Basel, Switzerland)

Histopathological Study of Host-Pathogen Interactions Between Cordyceps javanica PSUC002 and Hypothenemus hampei.

The use of entomopathogenic fungi (EPF), such as Cordyceps javanica, to reduce insect pest populations is gaining traction since it is an environmentally safe approach that can control many pests at different life stages..

Energy & fatigueMetabolic health