MycoData

Endo-beta-N-acetylglucosaminidases are thought to be key enzymes in the catabolism of asparagine-linked oligosaccharides. However, little is known about the enzymes of this type in basidiomycetes..

Medium relevance

Mesima · 2010 · Research Support, Non U.S. Gov'T · Phytotherapy research: PTR

The ethyl acetate extract of Phellinus linteus grown on germinated brown rice induces G0/G1 cell cycle arrest and apoptosis in human colon carcinoma HT29 cells.

It is well known that Phellinus linteus has a variety of biological functions, such as antitumor and immunomodulating activities. In our previous studies, we developed a P..

OncologyImmune supportGut & microbiome

Medium relevance

Niu-Chang-Chih · 2010 · Patent · journal metadata

WATER EXTRACT OF ANTRODIA CAMPHORATA FOR IMMUNOSTIMULATORY EFFECT AND PREPARATION METHOD THEREOF

A preparation method for a water extract of the fruiting body of Antrodia camphorata (ACW) is provided. The method includes steps of: (a) providing the fruiting body and (b) boiling the fruiting body in water to obtain the water extract.

OncologyImmune support

Medium relevance

Enoki · 2009 · English Abstract · Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials

[Effect of Flammulina velutipes polysaccharides on production of cytokines by murine immunocytes and serum levels of cytokines in tumor-bearing mice].

OBJECTIVE: To study the effect of Flammulina velutipes polysaccharides (FVP) on the production of tumor necrosis factor alpha (TNF-alpha), interferon-gamma (INF-gamma) and interleukin 2 (IL-2) by murine immunocytes..

OncologyImmune supportMetabolic health

Medium relevance

Niu-Chang-Chih · 2009 · Research Support, Non U.S. Gov'T · International heart journal

A novel inhibitory effect of Antrodia camphorata extract on vascular smooth muscle cell migration and neointima formation in mice.

Antrodia camphorata (AC) is a well-known traditional Chinese medicine that has been shown to inhibit proliferation and migration of cancer cells. We examined whether AC could inhibit rat aortic smooth muscle cell (RASMC) proliferation and migration and evaluated its effect on neointima formation in mouse carotid….

OncologyEnergy & fatigueSkin & hydration

Medium relevance

Chaga · 2009 · Research Support, Non U.S. Gov'T · Bioresource technology

Accumulation of antioxidant phenolic constituents in submerged cultures of Inonotus obliquus.

Phenolic compounds produced by sclerotia of Inonotus obliquus are the active constituents responsible for antioxidant activities. In this study, I.

Skin & hydration

Medium relevance

Niu-Chang-Chih · 2009 · Research Support, Non U.S. Gov'T · Archives of toxicology

Active extracts of wild fruiting bodies of Antrodia camphorata (EEAC) induce leukemia HL 60 cells apoptosis partially through histone hypoacetylation and synergistically promote anticancer effect of trichostatin A.

The endemic species of Antrodia camphorate (AC) is a promising chemotherapeutic drug for cancer. We found that the ethanol extract from wild fruiting bodies of Antrodia camphorata (EEAC) could induce HL 60 cells apoptosis via histone hypoacetylation, up-regulation of histone deacetyltransferase 1 (HDAC 1), and….

Oncology

Medium relevance

Maitake · 2009 · Research Support, Non U.S. Gov'T · Biological trace element research

Activity and toxicity of Cr(III)-enriched Grifola frondosa in insulin-resistant mice.

This study was designed to evaluate the effect of administration of chromium-enriched Grifola frondosa (CEGF) in insulin-resistant sucrose-fed mice. Mice were randomly assigned to be unsupplemented (S group) or to receive oral CEGF at a dose of 0.5, 1.0, 2.0, 3.0, 4.0, and 5.0 mg/kg per day chromium..

Metabolic health

Medium relevance

Maitake · 2009 · Research Support, Non U.S. Gov'T · Carbohydrate research

An unambiguous structural elucidation of a 1,3-beta-D-glucan obtained from liquid-cultured Grifola frondosa by solution NMR experiments.

Grifolan LE (GRN-LE), a purified beta-D-glucan, which is obtained from liquid-cultured Grifola frondosa, exhibits various biological activities, including antitumor effects. Significant progress has been made in the study of these effects..

OncologyImmune support

Medium relevance

Mesima · 2009 · Research Support, Non U.S. Gov'T · BMB reports

Anti-oxidative effects of Phellinus linteus and red ginseng extracts on oxidative stress-induced DNA damage.

Anti-oxidative effect of Phellinus linteus (P. linteus) and red ginseng extracts on DNA damage induced by reactive oxygen species (ROS) were investigated in this study.

Energy & fatigueLiver support

Medium relevance

Chaga · 2009 · Research Support, Non U.S. Gov'T · International journal of food sciences and nutrition

Antioxidant activities of extracts and subfractions from Inonotus Obliquus.

The ethanolic crude extracts and three subfractions (ethyl acetate fraction, n-butanol fraction, and aqueous fraction) from Inonotus Obliquus were obtained by sequential partitioning and their antioxidant activities were investigated in the present study..

Medium relevance

Wood Ear · 2009 · Research Support, Non U.S. Gov'T · Journal of medicinal food

Antioxidant capacity of fresh and processed fruit bodies and mycelium of Auricularia auricula-judae (Fr.) Quél.

Auricularia auricula-judae is currently grown in Malaysia. In the present study, the methanolic extracts from fruit bodies (fresh, oven-dried, and freeze-dried) and mycelium of A..

Medium relevance

Enoki · 2009 · Research Support, Non U.S. Gov'T · Journal of food science

Antioxidative activities of mushroom (Flammulina velutipes) extract added to bigeye tuna meat: dose-dependent efficacy and comparison with other biological antioxidants.

The ability of a hydrophilic extract prepared from edible mushroom (Flammulina velutipes) to stabilize fresh color of bigeye tuna (Thunnus obesus) meat was evaluated to compare it with certain other antioxidants..

Medium relevance

Niu-Chang-Chih · 2009 · Patent · journal metadata

Compound from Antrodia camphorata and the use thereof

The present invention relates to novel compounds from Antrodia camphorata and the use thereof..

Medium relevance

Turkey Tail · 2009 · Research Support, Non U.S. Gov'T · Bioresource technology

Contribution of the saprobic fungi Trametes versicolor and Trichoderma harzianum and the arbuscular mycorrhizal fungi Glomus deserticola and G. claroideum to arsenic tolerance of Eucalyptus globulus.

The presence of high concentrations of arsenic (As) decreased the shoot and root dry weight, chlorophyll and P and Mg content of Eucalyptus globulus colonized with the arbuscular mycorrhizal (AM) fungi Glomus deserticola or G. claroideum, but these parameters were higher than in non-AM plants..

Gut & microbiome

Medium relevance

Maitake · 2009 · Research Support, Non U.S. Gov'T · New biotechnology

Cultivation and bioactivity assessment of Grifola frondosa fruiting bodies on olive oil press cakes substrates.

Grifola frondosa, a medicinal and edible mushroom, was cultivated on substrates composed of olive oil press cakes with different supplements. Crude extracts were prepared from mature fruiting bodies and tested for their capacity to stimulate splenocyte proliferation..

Medium relevance

Niu-Chang-Chih · 2009 · Research Support, Non U.S. Gov'T · Electrophoresis

Cyclodextrin-modified capillary electrophoresis for achiral and chiral separation of ergostane and lanostane compounds extracted from the fruiting body of Antrodia camphorata.

A CD-modified capillary electrophoretic method has been developed for achiral and chiral analysis of seven bioactive compounds isolated from the fruiting body of Antrodia camphorata..

Oncology

Medium relevance

Niu-Chang-Chih · 2009 · Research Support, Non U.S. Gov'T · Cancer letters

Cytotoxic triterpenes from Antrodia camphorata and their mode of action in HT-29 human colon cancer cells.

Five lanostane (2, 3, 4, 6 and 8) and three ergostane-type (1, 5 and 7) triterpenes isolated from the fruiting bodies of Antrodia camphorata were evaluated for their in vitro cytotoxic data against various cancer cell types..

OncologyGut & microbiome

Medium relevance

Niu-Chang-Chih · 2009 · Patent · journal metadata

Diterpenes from the fruiting body of Antrodia camphorata and pharmaceutical compositions thereof

The present invention relates to novel diterpene compounds isolated from the fruiting body of Antrodia camphorata, especially to the new compounds of following structural formula: and pharmaceutically acceptable salt, solvate, hydrate or biologically active equivalent thereof..

Cognition & nerves

Medium relevance

Snow Fungus · 2009 · Research Support, Non U.S. Gov'T · Applied biochemistry and biotechnology

Effect of constant glucose feeding on the production of exopolysaccharides by Tremella fuciformis spores.

A fed-batch culture system with constant feeding (glucose 80 g L(-1), 0.25 ml min(-1)) was used to study the influence of glucose on cell dry weight and exopolysaccharides production from submerged Tremella fuciformis spores in a 5-L stirred-tank bioreactor..

Immune supportMetabolic health

Medium relevance

Niu-Chang-Chih · 2009 · Research Support, Non U.S. Gov'T · The Chinese journal of physiology

Effects of Antrodia camphorata extracts on the viability, apoptosis, [Ca2+]i, and MAPKs phosphorylation of OC2 human oral cancer cells.

The effect of Antrodia camphorata (AC) on human oral cancer cells has not been explored. This study examined the effect of AC on the viability, apoptosis, mitogen-activated protein kinases (MAPKs) phosphorylation and Ca2+ regulation of OC2 human oral cancer cells..

OncologyImmune support

Medium relevance

Turkey Tail · 2009 · Comparative Study · Biotechnology letters

Gravimetric screening method for fungal decay of paper: inoculation with Trametes versicolor.

The European standard test EN 113 for fungal degradation of solid wood has been adapted for degradation of paper by white rot fungus (Trametes versicolor). Fungal degradation of paper sheets may potentially be used for screening different wood preservatives on paper instead of solid wood..

Medium relevance

Maitake · 2009 · Patent · journal metadata

GRIFOLA FRONDOSA EXTRACT AND COMPOSITION CONTAINING THE SAME FOR PROMOTING THE PRODUCTION OF HYALURONIC ACID (HYALURONAN)

To provide a Grifola frondosa extract which more effectively promotes the production of hyaluronic acid (hyaluronan) and a composition containing the same. A G.

Skin & hydration

Medium relevance

Maitake · 2009 · Research Support, Non U.S. Gov'T · Biological trace element research

Hypoglycemic activity of Grifola frondosa rich in vanadium.

The hypoglycemic activity of fermented mushroom of Grifola frondosa rich in vanadium (GFRV) was studied in this paper. Alloxan- and adrenalin-induced hyperglycemic mice were used in the study.

Metabolic health

Medium relevance

Enoki · 2009 · Research Support, Non U.S. Gov'T · Journal of microbiology and biotechnology

Isolation of 1',3'-dilinolenoyl'-2'-linoleoylglycerol with tyrosinase inhibitory activity from Flammulina velutipes.

This study was carried out to evaluate the inhibitory effect of Flammulina velutipes extracts on tyrosinase activity and to identify its biologically active component. The ethyl acetate and n-butanol extracts showed potent tyrosinase inhibitory activities..

Medium relevance

Turkey Tail · 2009 · Research Support, Non U.S. Gov'T · Chemosphere

Metabolites from the biodegradation of triphenylmethane dyes by Trametes versicolor or laccase.

The feasibility of degrading triphenylmethane dyes by Trametes versicolor and laccase has been investigated for the following dyes: Acid Fuchsin, Brilliant Green 1, Basic Fuchsin, Methyl Green or Acid Green 16..

Medium relevance

Niu-Chang-Chih · 2009 · Research Support, Non U.S. Gov'T · Planta medica

New constituents with iNOS inhibitory activity from mycelium of Antrodia camphorata.

In continuing our investigation on the bioactive constituents of mycelium of Antrodia camphorata, antroquinonol B (1), 4-acetyl-antroquinonol B (2), 2,3-(methylenedioxy)-6-methylbenzene-1,4-diol (3) and 2,4-dimethoxy-6-methylbenzene-1,3-diol (4) along with antrodin D (5) were isolated by the guidance of an inducible….

OncologyImmune support

Medium relevance

Chaga · 2009 · Research Support, Non U.S. Gov'T · Microbiology (Reading, England)

Nitric oxide mediates the fungal-elicitor-enhanced biosynthesis of antioxidant polyphenols in submerged cultures of Inonotus obliquus.

A fungal elicitor prepared from the cell debris of the plant-pathogenic ascomycete Alternaria alternata induces multiple responses by Inonotus obliquus cells, including an increase in generation of nitric oxide (NO), activity of phenylalanine ammonia lyase (PAL) and accumulation of total mycelial phenolic compounds….

Cognition & nerves

Medium relevance

Chaga · 2009 · Research Support, Non U.S. Gov'T · Bioresource technology

NMR-based metabonomic analysis on effect of light on production of antioxidant phenolic compounds in submerged cultures of Inonotus obliquus.

This study was designed to investigate the light effect on biosynthesis of antioxidant phenolic compounds by Inonotus obliquus grown in submerged cultures using (1)H NMR spectroscopy combining multivariate pattern recognition strategies. I..

Cognition & nervesMetabolic health

Medium relevance

Niu-Chang-Chih · 2009 · Patent · journal metadata

Novel compounds from antrodia camphorata

Antroquinonol B (X=OH) and Antroquinonol C (X=OMe) are described. They can be isolated from Antrodia camphorata extracts and may inhibit the growth of cancer cells (e.g.

OncologyLiver supportRespiratory

Medium relevance

Turkey Tail · 2009 · Research Support, U.S. Gov'T, Non P.H.S. · Bioresource technology

Oxidation of anthracene by immobilized laccase from Trametes versicolor.

The laccase of Trametes versicolor was immobilized on the functionalized nanoparticles SBA-15 with the average diameter less than 10 nm. Laccase mediated oxidations of anthracene (ANT) were investigated in the presence of two mediators, 2,2'-azino-bis-(3-ethylbenzothiazoline-6-sulphonic acid) diammonium salt (ABTS)….

OncologyImmune support

Medium relevance

Chaga · 2009 · Research Support, Non U.S. Gov'T · Medical mycology

Oxidative stress response of Inonotus obliquus induced by hydrogen peroxide.

While the medicinal fungus Inonotus obliquus produces polyphenols as one of its main metabolites in natural habitats, it accumulates less polyphenols under laboratory conditions..

Skin & hydration

Medium relevance

Maitake · 2009 · Patent · journal metadata

Preparation method of r grifola frondosa compost

The invention relates to a preparation method of grifola frondosa compost which comprises the following components by weight percent: 45 percent to 55 percent of cotton seed hulls, 4 percent to 12 percent of soybean cake, 3 percent to 9 percent of corn flour, 4 percent to 12 percent of corncob, 3 percent to 9 percent….

Energy & fatigue

Medium relevance

Enoki · 2009 · Research Support, Non U.S. Gov'T · Bioscience, biotechnology, and biochemistry

Properties of Ethanol Fermentation by Flammulina velutipes

Basidiomycetes have the ability to degrade lignocellulosic biomass, and some basidiomycetes produce alcohol dehydrogenase. These characteristics may be useful in the direct production of ethanol from lignocellulose..

Metabolic health

Medium relevance

Niu-Chang-Chih · 2009 · Patent · journal metadata

Protein ACA1 of antrodia camphorata

A new protein, named ACA1, has been isolated and purified from the medical fungi Antrodia camphorata using the technique of anion-exchange chromatography. ACA1, a glycoprotein with a molecular mass of 29 kDa, has a pI value of pH 5.3 and contains 118 amino acids in its peptide moiety..

OncologyImmune support

Medium relevance

Niu-Chang-Chih · 2009 · Research Support, Non U.S. Gov'T · Journal of agricultural and food chemistry

Purification, cloning, and functional characterization of a novel immunomodulatory protein from Antrodia camphorata (bitter mushroom) that exhibits TLR2-dependent NF-κB activation and M1 polarization within murine macrophages.

A new immunomodulatory protein, designated ACA, was purified from the mycelium extract of Antrodia camphorata, a well-known folk medicine bitter mushroom in Taiwan, and N-terminally sequenced..

Immune support

Medium relevance

Turkey Tail · 2009 · Research Support, Non U.S. Gov'T · Preparative biochemistry & biotechnology

Pyranose 2-oxidase (P2O): production from trametes versicolor in stirred tank reactor and its partial characterization.

Optimization of pyranose-2-oxidase (P2O) production conditions from Trametes versicolor was carried out in shaking cultures containing glucose, malt, and yeast extracts; the optimum concentration values were found to be 1.5% glucose, 1.0% yeast extract, and 1.0% malt extract, pH 5.0, temperature, 26 degrees C, and….

Energy & fatigueMetabolic health

Medium relevance

Zhu Ling · 2009 · Research Support, Non U.S. Gov'T · Die Pharmazie

Qualitative and quantitative analysis of the diuretic component ergone in Polyporus umbellatus by HPLC with fluorescence detection and HPLC-APCI-MS/MS.

Polyporus umbellatus is a widely used anti-aldosteronic diuretic in Traditional Chinese medicine (TCM). A new, sensitive and selective high-performance liquid chromatography-fluorescence detector (HPLC-FLD) and high-performance liquid chromatography-atmospheric pressure chemical ionization-mass spectrometry….

Energy & fatigue

Medium relevance

Niu-Chang-Chih · 2009 · Research Support, Non U.S. Gov'T · ChemMedChem

Rapid evaluation of Antrodia camphorata natural products and derivatives in tumourigenic liver progenitor cells with a novel cell proliferation assay.

We report the syntheses of five natural product maleimide and maleic anhydrides from the mushroom Antrodia camphorata. The ability of these compounds to affect proliferation in non-tumourigenic and tumourigenic liver progenitor cell lines was monitored by the Cellscreen system, a novel and nondestructive….

OncologyLiver support

Medium relevance

Enoki · 2009 · Research Support, Non U.S. Gov'T · Zeitschrift fur Naturforschung. C, Journal of biosciences

Selenium accumulation in mycelia of Flammulina velutipes during fermentation determined by RP-HPLC.

A method to estimate the content of selenium in organics was introduced based on reversed phase-high performance liquid chromatography (RP-HPLC).The maximum absorption peak of piazselenol was at 330 nm and the optimized temperature and pH value were 40 degrees C and 2.8, respectively..

Energy & fatigue

Medium relevance

Niu-Chang-Chih · 2009 · Research Support, Non U.S. Gov'T · The American journal of Chinese medicine

The augmented anti-tumor effects of Antrodia camphorata co-fermented with Chinese medicinal herb in human hepatoma cells.

Antrodia camphorata, unique fungal specie, has been used as a folk medicine in Taiwan for many years. The purpose of this study was to compare the extracts from the solid-state culture of A..

OncologyLiver support

Medium relevance

Enoki · 2009 · Research Support, Non U.S. Gov'T · Bioscience, biotechnology, and biochemistry

Use of Whole Crop Sorghums as a Raw Material in Consolidated Bioprocessing Bioethanol Production Using Flammulina velutipes

The possibility of using two kinds of sorghum as raw materials in consolidated bioprocessing bioethanol production using Flammulina velutipes was investigated. Enzymatic saccharification of sweet sorghum was not as high as in brown mid-rib (bmr) mutated sorghum, but the amount of ethanol production was higher..

Medium relevance

Niu-Chang-Chih · 2008 · Patent · journal metadata

4-hydroxy-2,3-disubstituted-cyclohex-2-en-1-on-5-yl isoprenoids, extractable from Antrodia camphorata, as anti-tumour & cardiovascular agents, & antioxidant

Compounds of formula (1): '''wherein: X and Y are O or S R' are independently H or C1-13 linear alkyl and n is 1-12 can be isolated and purified from an extract of Antrodia camphorata, and used to inhibit the growth of cancer cells (such as breast cancer, hepatic cancer and prostate cancer), to prevent heart disease….

OncologyLiver support

Medium relevance

Niu-Chang-Chih · 2008 · Research Support, Non U.S. Gov'T · Journal of agricultural and food chemistry

Anti-inflammatory activities of new succinic and maleic derivatives from the fruiting body of Antrodia camphorata.

Six new compounds, trans-3-isobutyl-4-[4-(3-methyl-2-butenyloxy)phenyl]pyrrolidine-2,5-dione (1), trans-1-hydroxy-3-(4-hydroxyphenyl)-4-isobutylpyrrolidine-2,5-dione (2), cis-3-(4-hydroxyphenyl)-4-isobutyldihydrofuran-2,5-dione (3), 3-(4-hydroxyphenyl)-4-isobutyl-1H-pyrrole-2,5-dione (4),….

Immune support

Medium relevance

Mesima · 2008 · Research Support, Non U.S. Gov'T · Journal of applied microbiology

Antioxidant polyphenols from the mycelial culture of the medicinal fungi Inonotus xeranticus and Phellinus linteus.

AIMS: The medicinal fungi Inonotus xeranticus and Phellinus linteus in the family Hymenochaetaceae have been used as traditional medicines for the treatment of various diseases. However, the compound responsible for the antioxidant activity is still unknown..

Medium relevance

Enoki · 2008 · Evaluation Study · Journal of agricultural and food chemistry

Antioxidative activity and antidiscoloration efficacy of ergothioneine in mushroom (Flammulina velutipes) extract added to beef and fish meats.

The antioxidative property of a hydrophilic extract prepared from the fruiting body of edible mushroom ( Flammulina velutipes) was evaluated. The mushroom extract contained ergothioneine (ERT) at a level of 3.03 +/- 0.07 mg/mL, showed higher 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging activity, and….

Medium relevance

Niu-Chang-Chih · 2008 · Research Support, Non U.S. Gov'T · Food and chemical toxicology: an international journal published for the British Industrial Biological Research Association

Antrodia camphorata inhibits proliferation of human breast cancer cells in vitro and in vivo.

Antrodia camphorata (A. camphorata) has been shown to induce apoptosis in cultured human breast cancer cells (MDA-MB-231).

OncologyImmune support

Medium relevance

Mesima · 2008 · Research Support, Non U.S. Gov'T · Journal of industrial microbiology & biotechnology

Bioconversion of starch processing waste to Phellinus linteus mycelium in solid-state cultivation.

The objective of the experiment was to use starch processing waste as an alternative growth medium for cultivation of mycelia of the mushroom Phellinus linteus and to find an optimum condition under solid-state cultivation..

Medium relevance

Turkey Tail · 2008 · Research Support, Non U.S. Gov'T · Journal of environmental science and health. Part A, Toxic/hazardous substances & environmental engineering

Biological decolourisation of wastewater from molasses fermentation by Trametes versicolor in an airlift reactor.

Continuous decolourisation of wastewater from molasses fermentation using mycelium of Trametes versicolor in pellets shape was performed in an airlift bioreactor (semi-pilot scale) with the aim of operating steadily for a long period, maintaining the colour removal activity..

Metabolic health

Medium relevance

Yellow Morel · 2008 · Case Reports · Clinical toxicology (Philadelphia, Pa.)

Cerebellar effects after consumption of edible morels (Morchella conica, Morchella esculenta).

Morchella esculenta and Morchella conica are well known edible morels, which seldom induce clinical symptoms. We report six persons who developed cerebellar effects 6-12 hours after consumption of these mushrooms.