MycoData

Almond Mushroom · 2019 · Randomized Controlled Trial · Child psychiatry and human development

Efficacy of Attention Bias Training for Child Anxiety Disorders: A Randomized Controlled Trial.

A growing evidence base supports attention bias modification (ABM) as a novel intervention for anxiety. However, research has been largely conducted with adults and analogue samples, leaving the impact of ABM for child anxiety be fully elucidated..

Cognition & nerves

Maitake · 2019 · Research Support, Non U.S. Gov'T · PloS one

Synergistic immuno-modulatory activity in human macrophages of a medicinal mushroom formulation consisting of Reishi, Shiitake and Maitake.

A key characteristic of mushroom polysaccharides that elicit an immunomodulatory response is that they are rich in β-glucans and low in α-glucans. In this study we analysed nine commercially available preparations from three mushroom species, Reishi (Ganoderma lucidum), Shiitake (Lentinula edodes) and Maitake (Grifola….

Cordyceps · 2017 · Research Support, Non U.S. Gov'T · Scientific reports

Fungus-larva relation in the formation of Cordyceps sinensis as revealed by stable carbon isotope analysis.

For more than one thousand years, Cordyceps sinensis has been revered as a unique halidom in the Qinghai-Tibetan Plateau for its mysterious life history and predominant medicinal values..

Gut & microbiome

Shiitake · 2017 · Research Support, Non U.S. Gov'T · Scientific reports

Lentinan from shiitake selectively attenuates AIM2 and non-canonical inflammasome activation while inducing pro-inflammatory cytokine production.

Lentinan extracted from shiitake (Lentinula edodes) is a β-glucan that has been reported as an intravenous anti-tumor polysaccharide via enhancement of the host immune system. In this study, we determined the effect of lentinan on inflammasome activation, a multi-protein platform, in myeloid cells..

OncologyImmune support

Immune supportEnergy & fatigue

Cordyceps · 2017 · Research Support, Non U.S. Gov'T · Trends in biotechnology

Myths and Realities Surrounding the Mysterious Caterpillar Fungus.

The caterpillar fungus Ophiocordyceps sinensis is a medicinal mushroom increasingly used as a dietary supplement for various health conditions, including fatigue, chronic inflammation, and male impotence..

OncologyImmune supportCognition & nervesMetabolic health

Enoki · 2016 · Review · Frontiers in pharmacology

Golden Needle Mushroom: A Culinary Medicine with Evidenced-Based Biological Activities and Health Promoting Properties.

Flammulina velutipes (enoki, velvet shank, golden needle mushroom or winter mushroom), one of the main edible mushrooms on the market, has long been recognized for its nutritional value and delicious taste..

Shiitake · 2014 · Journal Article · Postepy dermatologii i alergologii

Flagellate dermatitis after consumption of Shiitake mushrooms.

Flagellate dermatitis occurs in patients who have eaten Shiitake mushrooms. We are reporting on a 55-year-old man, who developed whiplash-striped, severely itching efflorescences on the trunk 3 days after eating Lentinula edodes.

Skin & hydration

OncologyImmune supportMetabolic healthGut & microbiome

Maitake · 2009 · Journal Article · International immunopharmacology

Maitake beta-glucan enhances therapeutic effect and reduces myelosupression and nephrotoxicity of cisplatin in mice.

Cisplatin is broadly used clinically as an anticancer drug. Despite its significant anticancer activity, cisplatin-induced nephrotoxicity and myelosuppression limit its use..

Chaga · 2005 · Patent · journal metadata

PREPARATION OF CHAGA-INFUSED TEA BY DRYING CHAGA AND MIXING WITH ROASTED UNPOLISHED RICE FLOUR, GREEN TEA POWDER, POLYGONATUM ODORATUM POWDER OR COFFEE

PURPOSE: A method of making Chaga-infused tea by drying Chaga(Inonotus obliquus) and mixing with roasted unpolished rice flour, green tea powder, Polygonatum odoratum powder or coffee after drying is provided..

Chaga · 2004 · Patent · journal metadata

BROILED CHAGA MUSHROOM EEL USING CHAGA MUSHROOM

PURPOSE: Broiled Chaga mushroom eel made by adding an extract of Chaga mushroom(Inonotus obliquus) during simmering or broiling an eel is provided. The product has the efficacy of Chaga mushroom as well the characteristic taste and flavor of broiled ell..

Chaga · 2004 · Research Support, Non U.S. Gov'T · BioFactors (Oxford, England)

Chaga mushroom extract inhibits oxidative DNA damage in human lymphocytes as assessed by comet assay.

The Chaga mushroom (Inonotus obliquus) is claimed to have beneficial properties for human health, such as anti-bacterial, anti-allergic, anti-inflammatory and antioxidant activities. The antioxidant effects of the mushroom may be partly explained by protection of cell components against free radicals..

Chaga · 2004 · Patent · journal metadata

CHAGA MUSHROOM FISH STEW USING EXTRACT OF CHAGA MUSHROOM IN PLACE OF WATER

PURPOSE: Chaga mushroom fish stew made by adding an extract of Chaga mushroom(Inonotus obliquus) in place of broth or water to conventional fish stew is provided. The product has characteristic taste and flavor of fish stew together with the immunization effect of Chaga mushroom..

Chaga · 2004 · Patent · journal metadata

CHAGA MUSHROOM POTATO SOUP MADE WITH PORK BACKBONES AND CHAGA MUSHROOM

PURPOSE: Chaga mushroom potato soup made with pork backbones and Chaga mushroom(Inonotus obliquus) instead of a conventional broth or water is provided. It has the characteristic taste and flavor of potato soup as well as efficacy of Chaga mushroom..

Chaga · 2004 · Patent · journal metadata

CHAGA MUSHROOM RICE USING CHAGA MUSHROOM EXTRACT IN PLACE OF WATER

PURPOSE: Chaga mushroom rice made by cooking rice or miscellaneous cereals with an extract of Chaga mushroom(Inonotus obliquus) in place of water is provided. Everyone containing an infant, a child, an adult or the elderly can obtain the efficacy of Chaga mushroom through the product..

Chaga · 2004 · Patent · journal metadata

CHAGA MUSHROOM SEAFOOD STEW USING EXTRACT OF CHAGA MUSHROOM IN PLACE OF WATER

PURPOSE: Chaga mushroom seafood stew made by adding an extract of Chaga mushroom(Inonotus obliquus) in place of water to conventional seafood stew is provided. Everyone containing an infant, a child, an adult or the elderly can obtain components having immunization effect of Chaga mushroom through the product..

Cordyceps · 2026 · Research Article · Fundamental research

Accumulation of the spontaneous and random mutations is causative of fungal culture degeneration.

Filamentous fungi frequently degenerate during subculturing, which manifests as the reduction or loss of conidiation, sexuality, secondary metabolite production, and/or virulence against hosts. The underlying mechanism of spontaneous fungal degeneration is still elusive..

Energy & fatigue

Immune supportEnergy & fatigueMetabolic healthLiver support

King Oyster · 2026 · Journal Article · International journal of biological macromolecules

Antidiabetic effects of Agaricus bisporus polysaccharide in HFD/STZ-induced mice.

Fungal polysaccharides have garnered attention for their antidiabetic potential. Here, we evaluated five edible fungal polysaccharides-Agaricus bisporus (ABP), Pleurotus eryngii (PEP), Boletus spp.

OncologyImmune supportSkin & hydration

Cordyceps · 2026 · Journal Article · International journal of molecular sciences

Antithrombotic Effects of Cordycepin-Enriched WIB-801CE via Inhibition of Thromboxane A2-Induced αIIbβ3 Activation and Thrombin-Mediated Fibrin Clot Retraction.

WIB-801CE, a standardized Cordyceps militaris extract containing 7.0% cordycepin, suppresses platelet activation induced by thrombin, collagen, and adenosine diphosphate (ADP)..

OncologyImmune supportEnergy & fatigueSkin & hydration

Cordyceps · 2026 · Journal Article · Journal of chromatography. A

Construction of porous adsorbent for selective enrichment of cis-diol-containing flavonoids and evaluation of green performance based on life cycle analysis.

Flavonoids exhibit anti-inflammatory, anti-cancer, antibacterial and anti-aging properties. However, their complex structures make the separation and purification of flavonoids pharmacologically significant..

Cordyceps · 2026 · Research Article · Drug design, development and therapy

Cordycepin Ameliorates Dextran Sulfate Sodium-Induced Ulcerative Colitis in Mice by Inhibiting IL-6/IL-6R-Mediated p38 MAPK and NF-κB Activation Through Adenosine A2A Receptor Stimulation.

BACKGROUND: Current ulcerative colitis (UC) therapies often cause adverse effects, and novel treatments are urgently needed. Cordycepin (COR), a bioactive compound from Cordyceps militaris, shows anti-inflammatory and intestinal protective potential, its precise role and mechanisms in UC remain unclear..

Metabolic healthGut & microbiome

Cordyceps · 2026 · Journal Article · Food research international (Ottawa, Ont.)

Cordycepin-mediated protection against bisphenol A-induced male reproductive toxicity via PI3K/mTOR/HIF-1α signaling.

Environmental endocrine disruptors, such as bisphenol A (BPA), pose significant threats to male reproductive health. Cordycepin, a bioactive nucleoside derived from Cordyceps militaris, has demonstrated antioxidant and bioregulatory effects; however, its protective role against BPA-induced reproductive toxicity….

King Oyster · 2026 · Journal Article · International journal of biological macromolecules

Deamidation promotes the combination of novel proteins with volatile compounds and improves their flavor characteristics.

The undesirable flavor of plant-based proteins severely limits their high-value utilization. Consequently, developing green flavor-modification techniques and clarifying their regulatory mechanisms are of great importance..

OncologyImmune supportLiver support

Cordyceps · 2026 · Journal Article · Journal of clinical laboratory analysis

Edible Fungus Compound Cordycepin Protects Against Acetaminophen-Induced Liver Injury.

BACKGROUND: Medicinal-edible natural products like Cordyceps militaris (C.militaris), a functional food rich in cordycepin (COR), are promising for health maintenance..

King Oyster · 2026 · Research Article · Gels (Basel, Switzerland)

Effect of Curdlan on the Structural Stability and Thermal Processing Properties of Mycelium-Based Gels Used in 4D-Printed Meat Analogs.

This study investigated the effects of curdlan (CUR) on the structural stability and thermal processing properties of Pleurotus eryngii mycelium-soy protein isolate-cassava starch gels used as bio-ink scaffolds for 4D-printed meat analogs..

Skin & hydration

OncologyImmune supportMetabolic health

Cordyceps · 2026 · Journal Article · Bioresource technology

Efficient production of cordycepin in engineered Saccharomyces cerevisiae.

Cordycepin (COR) is an important bioactive nucleoside with antitumor and immunomodulatory activities, but its conventional production via Cordyceps militaris fermentation is limited by long cultivation periods and low titers. Therefore, microbial heterologous synthesis represents an attractive alternative..

Immune supportEnergy & fatigueMetabolic healthGut & microbiome

Cordyceps · 2026 · Journal Article · Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Elucidation of mechanisms underlying the therapeutic effects of cordycepin on pulmonary hypertension, with a focus on cell senescence and gut microbiota.

INTRODUCTION: Pulmonary hypertension (PH) is a progressive cardiopulmonary disorder characterized by excessive pulmonary vascular remodeling and aberrant proliferation of pulmonary artery smooth muscle cells (PASMCs). Emerging evidence suggests that gut microbiota dysbiosis contributes to PH development..

King Oyster · 2026 · Journal Article · Food science and biotechnology

Enhancing technofunctional properties of an emulsion-type meat analog formulated with mealworm and TVP: mushroom incorporation at the optimal concentration.

UNLABELLED: Mushrooms are commonly used as functional additives in meat products and show promise in alternative protein development. This study evaluated the impact of five mushroom species-Ganoderma lucidum, Pleurotus eryngii, Pleurotus ostreatus, Agaricus bisporus, and Lentinula edodes-at 3% concentration on the….

Immune supportEnergy & fatigueRespiratory

Shiitake · 2026 · Research Article · Frontiers in immunology

Evaluation of Imoviral® effects on early immune response in Sparus aurata challenged with Vibrio anguillarum.

BACKGROUND: An acute phase response (APR) was experimentally induced in Sparus aurata (Linnaeus, 1758) by intraperitoneal (IP) injection of Vibrio anguillarum to evaluate the effects of dietary supplementation with the Imoviral® complex (CRISTALFARMA) on fish growth performance and health status, through the analysis….

King Oyster · 2026 · Journal Article · Food chemistry

Facile fabrication of chitin-glucan nanofibers from four edible mushroom species using deep eutectic solvent and their adsorption characterization.

Mushrooms are an underexplored source of chitin-based biopolymers. Here, chitin-glucan nanofibers (CGNFs) were fabricated from four widely consumed mushrooms: Flammulina velutipes, Agaricus bisporus, Lentinula edodes, and Pleurotus eryngii..

Energy & fatigueGut & microbiome

Oyster Mushroom · 2026 · Journal Article · Journal of environmental management

Feasibility of soilless substrate systems supplemented with black soldier fly frass for sustainable mushroom cultivation.

The rising cost and limited availability of sawdust have driven interest in alternative substrates for mushroom cultivation. Black soldier fly larvae (BSFL) frass is a nutrient-rich byproduct of insect farming that could serve as a low-cost supplement, however, its effective incorporation requires a suitable substrate….

Shiitake · 2026 · Research Article · Journal of fungi (Basel, Switzerland)

Functional Annotation Workflow for Fungal Transcriptomes.

Although RNA sequencing (RNA-seq) enables rapid transcriptome profiling, functional annotation of fungal transcriptomes remains challenging. Existing tools prioritize broad taxonomic coverage, and reference genomes are scarce for non-model species..

Immune supportGut & microbiomeRespiratory

Reishi · 2026 · Research Article · Chinese medicine

Guominkang formula alleviates airway inflammation in HDM-induced asthma mice by regulating Wnt/β-Catenin pathway.

BACKGROUND: The Guominkang formula (GMK), formulated according to the principle of "treatment based on constitution differentiation," comprises Prunus mume (Siebold) Siebold & Zucc. (Wumei), Saposhnikovia divaricata (Turcz.

Cordyceps · 2026 · Research Article · Toxics

Integrating Speciation Analysis and Bioaccessibility to Reassess Cadmium Exposure Risk from Six Mushrooms.

Accurate assessment of dietary exposure to cadmium in mushrooms is crucial for food safety. The inherent limitation lies in relying solely on total cadmium content, failing to reflect its actual bioaccessibility.

King Oyster · 2026 · Journal Article · Innovative Food Science and Emerging Technologies

Mycelial growth stimulus-responsive 4D printing: A novel approach for mycelium-based meat analogs fabrication

Mycelium emerges as a promising sustainable biomaterial for meat analogs, owing to its fibrous structure and rich nutritional profile. This study introduces a novel 4D printing approach that leverages mycelial growth as a biological stimulus to fabricate mycelium-based meat analogs..

Gut & microbiome

Immune supportEnergy & fatigueLiver supportSkin & hydration

Cordyceps · 2026 · Journal Article · Journal of ethnopharmacology

Paecilomyces hepiali Chen (Cs-4) polysaccharides ameliorate chronic liver fibrosis via inhibiting TGF-β1/Smad and NLRP3/Caspase-1-mediated hepatic stellate cells activation in vivo and in vitro.

ETHNOPHARMACOLOGICAL RELEVANCE: Paecilomyces hepiali Chen (Cs-4), recognized as the classic deficiency-tonifiying medicine of traditional Chinese medicine (TCM), is the principal and most valuable medicinal species of Ophiocordyceps sinensis (known as Cordyceps sinensis (Berk.) Sacc., or 'Dong-Chong-Xia-Cao' in….

Cordyceps · 2026 · Journal Article · International journal of biological macromolecules

Physicochemical, structural, digestive stability, and microbiota effects of five edible mushroom polysaccharides (EMPs).

EMPs are widely used for their food-medicine characteristics and bioactivities. However, the lack of unified standards has resulted in inconsistent product quality..

Cordyceps · 2026 · Journal Article · Current microbiology

Selective Carbohydrate Modulation Enhances BLIS-Mediated Bioprotection Against Multidrug-Resistant Foodborne Pathogens During Vegetable Fermentation.

Lactic acid bacteria (LAB) play a pivotal role in food fermentation by shaping microbial ecosystems and enhancing product safety through the production of antimicrobial metabolites..

Shiitake · 2026 · Journal Article · Scientific reports

Temporal patterns of radiocesium decline in current-year branches of coppiced Quercus serrata relative to stand age after the Fukushima nuclear accident.

Forest contamination by radiocesium (137Cs) has hindered the resumption of forestry activities after the Fukushima nuclear accident, particularly the production of coppiced konara oak (Quercus serrata) bed logs for shiitake mushroom (Lentinula edodes) cultivation..

Oyster Mushroom · 2026 · Research Article · World journal of microbiology & biotechnology

Utilization of lignocellulosic mushroom cultivation residues for bioethanol production via consolidated bioprocessing.

In the context of the energy transition, there is an increasing need for research focused on low-cost feedstocks, such as lignocellulosic biomass, and on process optimization for the sustainable production of biofuels. Traditionally, processing lignocellulosic materials requires multiple stages..

Energy & fatigue

King Oyster · 2025 · Research Article · ACS agricultural science & technology

Assessment of Different Strategies for Composting of the Two-Phase Olive Mill Solid Waste: A Demonstrative Scale.

Thousands of tons of two-phase olive mill solid waste (2P-OMSW) are generated annually, necessitating effective valorization strategies. Composting has been widely explored as a management approach; however, the extended processing time required for these residues poses a significant challenge for the olive industry..

Cordyceps · 2025 · Research Article · Foods (Basel, Switzerland)

Bioactive Polysaccharides Prevent Lipopolysaccharide-Induced Intestinal Inflammation via Immunomodulation, Antioxidant Activity, and Microbiota Regulation.

Intestinal inflammation involves barrier impairment, immune hyperactivation, and oxidative stress imbalance. Bioactive polysaccharides universally alleviate inflammation via anti-inflammatory, antioxidant, and microbiota-modulating effects, yet exhibit distinct core mechanisms..

Immune supportEnergy & fatigue

King Oyster · 2025 · Journal Article · International journal of biological macromolecules

Blending polysaccharides from three edible mushrooms represents a promising approach for augmenting their anti-oxidant and anti-fatigue activities.

It has been well documented that a number of polysaccharides with potent free-radical scavenging capability possess notable anti-fatigue activity. Interestingly, recent evidence also suggested mixed polysaccharides derived from multiple sources may yield augmented bioactivities compared to the polysaccharides from a….

King Oyster · 2025 · Journal Article · Carbohydrate polymers

Chemical structure characterization of polysaccharides using diffusion ordered NMR spectroscopy (DOSY)

The potential of DOSY NMR spectroscopy to distinguish the linkage pattern of chemically related polysaccharides was evaluated using β-glucans isolated from yeast (Saccharomyces cerevisiae) and mushroom (Pleurotus eryngii). Laminarin from Laminaria digitata was included for chemical shift comparison..

King Oyster · 2025 · Journal Article · Carbohydrate polymers

Chemical structure characterization of polysaccharides using diffusion ordered NMR spectroscopy (DOSY).

Immune supportMetabolic health

Cordyceps · 2025 · Research Article · Bioresources and bioprocessing

Comparative evaluation of free radical scavenging activity and total metabolite profiles among 30 macrofungi species.

The high antioxidant content of mushrooms such as polyphenols, polysaccharides, carotenoids, ergothioneine, glutathione, vitamins, and other compounds, has sparked interest in their potential use in preventive and therapeutic medicine..

King Oyster · 2025 · Research Article · Journal of animal physiology and animal nutrition

Conversion of Lignocellulosic Biomass Into Valuable Feed for Ruminants Using White Rot Fungi.

White rot fungi can degrade lignin and improve the nutritional value of highly lignified biomass for ruminants. We screened for excellent fungi-biomass combinations by investigating the improvement of digestibility of wheat straw, barley straw, oat straw, rapeseed straw, miscanthus, new reed, spent reed from thatched….

Gut & microbiome

Immune supportMetabolic healthSkin & hydration

Cordyceps · 2025 · Journal Article · Molecular immunology

Cordycepin ameliorates high glucose-induced proliferation, inflammation, and extracellular matrix deposition in glomerular mesangial cells through Smad7-dependent manner.

Diabetic nephropathy (DN) is one of the most common causes of end-stage renal disease. The extracellular matrix deposition is potent pathogenic factors of renal fibrosis and injury.

OncologyImmune supportSkin & hydration

Cordyceps · 2025 · Journal Article · Molecular biotechnology

Cordycepin Ameliorates Psoriasis-Like Skin Lesion by Regulating p53/MDM2 Feedback Loop.

Apoptosis is a natural physiological process of programmed cell death. It is essential for maintaining the homeostasis of the body and the immune system.