MycoData

Immune supportMetabolic healthLiver support

Mesima · 2012 · Research Article · Chinese medicine

Protective effect of Phellinus linteus polysaccharide extracts against thioacetamide-induced liver fibrosis in rats: a proteomics analysis.

BACKGROUND: The hepatoprotective potential of Phellinus linteus polysaccharide (PLP) extracts has been described. However, the molecular mechanism of PLP for the inhibition of liver fibrosis is unclear..

Enoki · 2012 · Journal Article · Carbohydrate polymers

Purification and structural investigation of a water-soluble polysaccharide from Flammulina velutipes

A novel water-soluble heteropolysaccharide FVP60-B was extracted from the fruiting bodies of Flammulina velutipes with boiling water and purified by Sephacryl S-300 and S-400, which molecular weight was estimated to be 1.3×10⁴Da by HPLC..

Immune supportEnergy & fatigueMetabolic health

Lion's Mane · 2012 · Journal Article · Carbohydrate polymers

Structure of a water-soluble heteropolysaccharide from fruiting bodies of Hericium erinaceus

A new heteropolysaccharide (HEPF4), with a molecular weight of 2.03×10⁴Da as determined by high-performance liquid chromatography (HPLC), was obtained from the fruiting bodies of Hericium erinaceus. It is composed of 3-O-methylrhamnose, l-fucose, d-galactose and d-glucose in the ratio of 0.12:1.00:3.27:0.28..

OncologyEnergy & fatigueMetabolic healthLiver support

Niu-Chang-Chih · 2012 · Research Article · Evidence-based complementary and alternative medicine: eCAM

Triterpenoid-Rich Extract from Antrodia camphorata Improves Physical Fatigue and Exercise Performance in Mice.

Antrodia camphorata (AC) is an endemic mushroom that grows in Taiwan. We investigated the fatigue-alleviating effects of AC on endurance capacity in swim-exercised and weight-loading mice..

Turkey Tail · 2011 · Journal Article · Canadian journal of animal science

Chemical characterization and in vitro fermentation of Brassica straw treated with the aerobic fungus, Trametes versicolor

Brassica napus straw (BNS) was either not treated or was treated with two strains of Trametes versicolor; 52J (wild type) or m4D (a cellobiose dehydrogenase-deficient mutant) with four treatments: (i) untreated control (C-BNS), (ii) 52J (B-52J), (iii) m4D (B-m4D) or (iv) m4D+glucose (B-m4Dg)..

Turkey Tail · 2011 · Journal Article · Prikladnaia biokhimiia i mikrobiologiia

GC-MS and spectrophotometric analysis of biodegradation of new disazo dye by Trametes versicolor.

In this study; sub-tropical white rot fungi, Trametes versicolor was investigated for its ability to degrade 4-(3'-methyl-4'-(4"-nitrophenyl)azo- 1'H-pyrazol-5'-ylazo)-3-methyl- H-pyrazol-5-on in the mediums containing glucose and different concentrations of degrade dye in batch systems..

OncologyImmune supportEnergy & fatigueMetabolic health

Mesima · 2010 · Journal Article · Archives of pharmacal research

Hispidin produced from Phellinus linteus protects pancreatic beta-cells from damage by hydrogen peroxide.

Phellinus linteus, which is a traditional medicinal mushroom used in Asian countries for the treatment of various diseases, has attracted a lot of attention due to its antioxidant, anti-inflammatory, anti-mutagenicity, and cell-mediated immunity properties in addition to its ability to inhibit tumor growth and….

Yellow Morel · 2010 · Journal Article · Carbohydrate polymers

Optimization for the production of exopolysaccharides from Morchella esculenta SO-02 in submerged culture and its antioxidant activities in vitro

The aims of this work were to optimize the conditions for exopolysaccharides (EPS) production by Morchella esculenta SO-02 in submerged culture, and to evaluate the antioxidant activities of EPS in vitro..

Yellow Morel · 2010 · Journal Article · World journal of microbiology & biotechnology

Solid-state fermentation of cornmeal with the ascomycete Morchella esculenta for degrading starch and upgrading nutritional value

The ability of the ascomycete Morchella esculenta to degrade starch and upgrade nutritional value of cornmeal during solid-state fermentation (SSF) was studied. On the basal medium, α-amylase activity of M.

OncologyImmune supportMetabolic healthGut & microbiome

Mesima · 2009 · Research Article · Mycobiology

Antitumor Effects and Immunomodulating Activities of Phellinus linteus Extract in a CT-26 Cell-Injected Colon Cancer Mouse Model.

The antitumor effects of Phellinus linteus extract (Keumsa Linteusan) were investigated in a CT-26 cell-injected colon cancer mouse model. When administered orally (250~1,000 mg/kg body weight), Keumsa Linteusan significantly inhibited the growth of solid colon cancer..

Metabolic healthGut & microbiome

Turkey Tail · 2009 · Journal Article · Chemosphere

Interactions of Trametes versicolor, Coriolopsis rigida and the arbuscular mycorrhizal fungus Glomus deserticola on the copper tolerance of Eucalyptus globulus.

The presence of high levels of Cu in soil decreases the shoot and root dry weights of Eucalyptus globulus. However, higher plant tolerance of Cu has been observed in the presence of the arbuscular mycorrhizal (AM) fungus Glomus deserticola.

Maitake · 2009 · Journal Article · Journal of bioscience and bioengineering

Properties and substrate specificities of proteolytic enzymes from the edible basidiomycete Grifola frondosa.

Highly active proteolytic enzymes are found in the fruiting bodies of Grifola frondosa. The general properties and substrate specificities of these proteases from G.

Turkey Tail · 2009 · Journal Article · Journal of hazardous materials

Statistical optimization for decolorization of textile dyes using Trametes versicolor.

The conventional treatment of dark coloured textile wastewater using chemical coagulation generates large volume of sludge, which requires further treatment and disposal..

Yellow Morel · 2008 · Journal Article · Food and chemical toxicology: an international journal published for the British Industrial Biological Research Association

Aqueous-ethanolic extract of morel mushroom mycelium Morchella esculenta, protects cisplatin and gentamicin induced nephrotoxicity in mice.

Morchella esculenta (L) Pers. is an excellently edible and delicious morel mushroom found growing in the temperate forests.

OncologyMetabolic healthGut & microbiome

Mesima · 2008 · Journal Article · Fitoterapia

Composition and proposed structure of a water-soluble glycan from the Keumsa Sangwhang Mushroom (Phellinus linteus).

Phellinus linteus is a mushroom which has been prized in Korea for its medicinal properties since ancient times. A glycan preparation from this source has shown promise in experimental anti-tumour and metastasis studies, but the glycan has not been well characterized..

Metabolic healthGut & microbiome

Mesima · 2008 · Research Article · Mycobiology

Cultural Characteristics and Log-Mediated Cultivation of the Medicinal Mushroom, Phellinus linteus.

The optimal conditions for mycelial growth of Phellinus linteus ATCC 26710 were determined to be a log length of 20 cm, temperature of 30℃ and pH of 6.0. Mycelial growth was excellent on the mushroom complete medium, and was optimal when sucrose, mannose and glucose were supplied as carbon sources..

Immune supportMetabolic healthGut & microbiome

Turkey Tail · 2008 · Journal Article · Wood Sci Technol

Effects of propiconazole on extra-cellular enzymes involved in nutrient mobilization during Trametes versicolor wood colonization

The effects of propiconazole on extra-cellular enzyme levels in Trametes versicolor have been investigated during wood colonization and degradation. The working hypothesis was that the biocide could alter metabolic pathways, which could lead to an alteration of extra-cellular enzyme production..

Lion's Mane · 2008 · Research Article · Mycobiology

Vegetative Growth of Four Strains of Hericium erinaceus Collected from Different Habitats.

Vegetative growth of four different strains of Hericium erinaceus was observed. The temperature suitable for optimal mycelial growth was determined to be 25℃, with growth observed in the extend temperature range of 20~30℃..

Wood Ear · 2007 · Research Article · Mycobiology

Hypolipidemic Effects of Biopolymers Extracted from Culture Broth, Mycelia, and Fruiting Bodies of Auricularia auricula-judae in Dietary-induced Hyperlipidemic Rats.

Hypolipidemic effect of biopolymers extracted from culture broth (CP), mycelia (MP), and fruiting bodies (FP) of Auricularia auricula-judae was investigated in dietary-induced hyperlipidemic rats. The experimental animals were administrated (100 mg/kg body weight) with different biopolymers, daily for 4 weeks..

Lion's Mane · 2007 · Journal Article · Food chemistry

Structural investigation of a novel fucoglucogalactan isolated from the fruiting bodies of the fungus Hericium erinaceus

A new heteropolysaccharide with a molecular weight of 1.94 x 10(4) Da, HEPF1, was isolated from the fruiting bodies of Hericium erinaceus. It is composed of fucose, galactose and glucose in the ratio of 1:4:1, as well as a minor proportion of 3-O-methyl rhamnose..

OncologyImmune supportEnergy & fatigueMetabolic health

Chaga · 2005 · Research Support, Non U.S. Gov'T · Journal of ethnopharmacology

In vivo and in vitro anti-inflammatory and anti-nociceptive effects of the methanol extract of Inonotus obliquus.

The mushroom Inonotus obliquus (Fr.) Pilát (Hymenochaetaceae), has been traditionally used for the treatment of gastrointestinal cancer, cardiovascular disease and diabetes in Russia, Poland and most of Baltic countries..

Chaga · 2005 · Patent · journal metadata

PREPARATION OF FUNCTIONAL RICE BY COATING PREWASHED RICE WITH EXTRACT OF CHAGA(INONOTUS OBLIQUUS)

PURPOSE: A method of making functional rice coated with a Chaga extract by coating prewashed rice with an extract of Chaga(Inonotus obliquus) is provided. The product is reinforced in [beta]-glucan and water-soluble lignin and has effects of improving immunity and reducing blood sugar levels..

Mesima · 2005 · Patent · journal metadata

PRODUCTION OF MYCELIAL CULTURE OF PAECILOMYCES TENUIPES, CORDYCEPS MILITARIS AND PHELLINUS LINTEUS INCREASED IN EXTRACELLULAR PROTEOGLYCAN

PURPOSE: A method of producing a mycelial culture of Paecilomyces tenuipes, Cordyceps militaris and Phellinus linteus using deep sea water rich in minerals instead of distilled water is provided. The culture is increased in extracellular proteoglycan while containing mineral components contained in deep sea water..

Chaga · 2004 · Patent · journal metadata

COMPOSITION FOR PREVENTION AND TREATMENT OF TYPE 1 AND TYPE 2 DIABETES, CONTAINING WATER EXTRACT OF CORDYCEPS MILITARIS AND INONOTUS OBLIQUUS AS EFFECTIVE INGREDIENT

PURPOSE: A pharmaceutical composition containing the water extract of Cordyceps militaris and Inonotus obliquus as an effective ingredient is provided. The composition exhibits excellent effect on various types of diabetes, in particular Type 1 and type 2 diabetes without causing any adverse side effect and is thus….

Lion's Mane · 2004 · Patent · journal metadata

HERICIUM ERINACEUS EXO-BIOPOLYMER HAVING HYPOLIPIDEMIC EFFECT, METHOD FOR ISOLATION OF THE SAME, AND USE THEREOF

PURPOSE: Hericium erinaceus exo-biopolymer having hypolipidemic effect, a method for isolation of the same, and the use thereof are provided, thereby reducing total cholesterol, triglyceride, phospholipid, arteriosclerosis index and LDL cholesterol concentration and maintaining high level of HDL cholesterol….

Chaga · 2004 · Patent · journal metadata

INONOTUS OBLIQUUS EXTRACT HAVING ANTIOXIDANT ACTIVITY AND LIPID METABOLISM IMPROVING EFFECT, EXTRACTION THEREOF AND USE THEREOF

PURPOSE: A water extract of mushroom such as Fuscoporia obliqua, Fuscoporia punctata or Inonotus obliquus having effects of increasing antioxidant activity and reducing free radical is provided..

Chaga · 2004 · Patent · journal metadata

INONOTUS OBLIQUUS EXTRACT HAVING ANTIOXIDANT EFFECT AND LIPID METABOLISM IMPROVING EFFECT, EXTRACTION THEREOF AND USE THEREOF

PURPOSE: A Fuscoporia obliqua extract obtained by extracting Fuscoporia obliqua, Fuscoporia punctata or Inonotus obliquus in water and then centrifuging is provided..

Mesima · 2004 · Patent · journal metadata

METHOD FOR PREPARING ADULT DISEASE PREVENTING MIXED JUICE CONTAINING PHELLINUS LINTEUS, WHEREIN THE ADULT DISEASE PREVENTING MIXED JUICE CONTAINING HAS ANTIOXIDATIVE, LIPID PEROXIDE INHIBITING AND ANTI-DIABETIC ACTIVITIES

PURPOSE: A method for preparing adult disease preventing mixed juice containing Phellinus linteus is provided, which adult disease preventing mixed juice has antioxidative, lipid peroxide inhibiting and anti-diabetic activities, so that it can be useful for prevention and treatment of aging, arteriosclerosis and….

OncologyImmune supportMetabolic health

Mesima · 2004 · Patent · journal metadata

PHARMACEUTICAL COMPOSITION FOR PREVENTION AND TREATMENT OF DISEASES ASSOCIATED WITH ANGIOGENESIS, CONTAINING POLYSACCHARIDE EXTRACTED FROM PHELLINUS LINTEUS

PURPOSE: A pharmaceutical composition containing polysaccharide such as galactomannoglucan extracted from the mycelium of Phellinus linteus as an effective ingredient is provided. The composition can be used for treatment of arthritis, diabetic retinopathy, psoriasis, cancer or the like..

Mesima · 2004 · Patent · journal metadata

RAPID CULTURING METHOD FOR PHELLINUS LINTEUS MYCELIUM USING GRAIN

PURPOSE: A method for rapidly culturing Phellinus linteus mycelium using a culture medium obtained by mixing cereals with a promoter such as glucose or the like is provided. Various kinds of cereals are used as a medium and the amount of culture products is be easily controlled..

Energy & fatigueMetabolic health

Niu-Chang-Chih · 2003 · Comparative Study · Life sciences

The vasorelaxation of Antrodia camphorata mycelia: involvement of endothelial Ca(2+)-NO-cGMP pathway.

Antrodia camphorata, a medicinal fungus, has been used to treat cardiovascular diseases such as hypertension for many years. The purpose of this study was to examine the effects of mycelia extracts, from five Antrodia camphorata strains, on vascular tension and underlying mechanisms were explored..

Maitake · 2002 · Research Support, Non U.S. Gov'T · FEMS microbiology letters

Molecular cloning and characterization of a cDNA encoding cellobiose dehydrogenase from the wood-rotting fungus Grifola frondosa.

Cloning of a cDNA encoding cellobiose dehydrogenase (CDH) from the wood-rotting fungus Grifola frondosa, which produces the edible maitake mushroom, was performed using reverse transcription-polymerase chain reaction (RT-PCR) and rapid amplification of cDNA ends..

King Oyster · 1999 · Comparative Study · The Biochemical journal

Molecular cloning of aryl-alcohol oxidase from the fungus Pleurotus eryngii, an enzyme involved in lignin degradation.

Aryl-alcohol oxidase (AAO), an extracellular enzyme characteristic of fungi from the genus Pleurotus, constitutes a source for H2O2 required in lignin biodegradation. The gene aao has been cloned, sequenced and characterized for the first time in Pleurotus eryngii..

Energy & fatigueMetabolic health

King Oyster · 1999 · Research Support, Non U.S. Gov'T · Applied and environmental microbiology

Regulation of peroxidase transcript levels in liquid cultures of the ligninolytic fungus Pleurotus eryngii.

A versatile peroxidase able to oxidize Mn(2+) as well as phenolic and nonphenolic aromatic compounds is produced in peptone-containing liquid cultures of Pleurotus eryngii encoded by the gene mnpl. The regulation of its transcript levels was investigated by Northern blotting of total RNA..

King Oyster · 1998 · Research Support, Non U.S. Gov'T · Applied and environmental microbiology

Electron and fluorescence microscopy of extracellular glucan and aryl-alcohol oxidase during wheat-straw degradation by Pleurotus eryngii.

The ligninolytic fungus Pleurotus eryngii grown in liquid medium secreted extracellular polysaccharide (87% glucose) and the H2O2-producing enzyme aryl-alcohol oxidase (AAO). The production of both was stimulated by wheat-straw..

OncologyImmune supportMetabolic healthSkin & hydration

Reishi · 2026 · Preprint · journal metadata

In Vitro and In Vivo Evaluation of the Skin-Care Bioactivity of β-1,3; 1,6-Glucans-Rich Ganoderma lucidum Polysaccharides

Extracted from Ganoderma lucidum mycelium, the developed β-1,3;1,6-glucan rich polysaccharides have the potential for industrial production of health food products due to their inhibition of metabolic syndrome, immunomodulatory and anti-tumor activities and other health benefits..

Energy & fatigueMetabolic health

Shiitake · 2026 · Evaluation Study · Food chemistry

Study on the mechanism of flavor development in ultrasound-assisted microwave vacuum drying of shiitake mushrooms: Dosage effect of ultrasonic amplitude.

In this study, the regulatory pathways of aroma formation in dried shiitake mushrooms under different ultrasound amplitudes (50 %, 70 %, and 90 %) were elucidated using GC-MS and non-targeted metabolomics combined with dynamic analysis of γ-GT and CS lyase activities..

OncologyImmune supportMetabolic healthGut & microbiome

Reishi · 2025 · Review · NPJ science of food

Application of edible fungi in gut microbiota regulation.

The human gut microbiota serves as a critical hub for host metabolic and immune regulation. Disruption of its homeostasis is closely associated with diseases such as Inflammatory Bowel Disease (IBD), metabolic syndrome, and colorectal cancer..

Immune supportMetabolic healthGut & microbiomeLiver support

Cordyceps · 2025 · Research Support, Non U.S. Gov'T · Molecular nutrition & food research

Cordyceps-Fermented Chinese Jujube Ameliorates Oxidative Stress and Restores Gut Microbiome in Alcohol-Induced Liver Injury in Mice.

This research investigated the influence of Chinese jujube fermented with Cordyceps kyushuensis extracts on mice with alcohol-induced liver injury (ALI). Our findings highlighted the antioxidant properties of these extracts through various assays and demonstrated potential biochemical effects in ALI mice..

OncologyMetabolic healthLiver supportSkin & hydration

Reishi · 2025 · Review · Frontiers in cellular and infection microbiology

Ganodermataceae-current status, research, and development in Lower Mekong Basin.

The family Ganodermataceae encompasses several genera, including the widely studied Ganoderma, which is prominent in traditional medicine for its therapeutic properties..

Immune supportCognition & nervesMetabolic healthGut & microbiome

Lion's Mane · 2025 · Review · Molecules (Basel, Switzerland)

Macromycete Edible Fungi as a Functional Poultry Feed Additive: Influence on Health, Welfare, Eggs, and Meat Quality-Review.

Over the years, macromycete fungi have been used as a source of food, part of religious rites and rituals, and as a medicinal remedy. Species with strong health-promoting potential include Hericium erinaceus, Cordyceps militaris, Ganoderma lucidum, Pleurotus ostreatus, Flammulina velutipes, and Inonotus obliquus..

Metabolic healthGut & microbiome

Shiitake · 2025 · Research Support, U.S. Gov'T, Non P.H.S. · The Journal of nutrition

Shiitake Mushroom as a Wholefood Supplementation in a Western Diet Modulates the Gut Microbiome, Serotonergic System, and Wnt Signaling to Promote Gut Health in Mice.

BACKGROUND: A Western-style diet (WD), typically high in fat and low in fiber and certain micronutrients, has been linked to a range of chronic diseases through its impact on gut health. Mushrooms exhibit a distinct nutritional profile that complements the deficiencies commonly associated with a WD..

Immune supportMetabolic healthGut & microbiome

Shiitake · 2025 · Preprint · journal metadata

Valorization of mushroom by-products for sustainability: exploring antioxidant and prebiotic properties

Agaricus bisporus (white button mushroom), Pleurotus ostreatus (oyster mushroom), and Lentinula edodes (shiitake mushroom) are the most cultivated mushrooms in the Spanish region of Castilla-La Mancha..

OncologyImmune supportCognition & nervesMetabolic health

King Oyster · 2024 · Preprint · journal metadata

Olive mill solid waste induces beneficial mushroom-specialized metabolite diversity revealed by computational metabolomics strategies

Introduction Mushrooms contain besides proteins a diverse pallet of specialized metabolites bioactive in either beneficial or harmful manner. Therefore, mushrooms have been exploited by humans for centuries for dietary or medical purposes..

Immune supportCognition & nervesEnergy & fatigueMetabolic health

Cordyceps · 2023 · Research Article · Molecules (Basel, Switzerland)

A New Galactoglucomannan from the Mycelium of the Medicinal Parasitic Fungus Cordyceps cicadae and Its Immunomodulatory Activity In Vitro and In Vivo.

A new galactoglucomannan (C-0-1) was purified from the medicinal parasitic fungus of Cordyceps cicadae using an anion-exchange column and gel permeation column. The results of high-performance liquid chromatography and high-performance gel permeation chromatography indicated that C-0-1 consists of galactose, glucose,….

OncologyImmune supportMetabolic healthRespiratory

Cordyceps · 2023 · Journal Article · Journal of natural medicines

Cordythiazole A, the first member of thiazole alkaloids from Chinese cordyceps, with α-glucosidase inhibitory activity.

Chinese cordyceps, also known as Dong-Chong-Xia-Cao, is widely recognized as a famous precious tonic herb, and used as traditional Chinese medicine for centuries..

Metabolic healthGut & microbiomeLiver support

Reishi · 2023 · Journal Article · Wiadomosci lekarskie (Warsaw, Poland: 1960)

EFFECT OF DRY EXTRACT FROM REISHI MUSHROOMS ON THE STATE OF ANTIOXIDANT SYSTEM IN RATS WITH DMH-INDUCED COLON CARCINOGENESIS.

OBJECTIVE: The aim: To study pro- and antioxidant systems indicators in rats with chemically induced colon carcinogenesis on the background of the reishi mushrooms dry extract use. PATIENTS AND METHODS: Materials and methods: The study was performed on 120 white male rats..

Shiitake · 2023 · Journal Article · Food chemistry

Effect of oxyresveratrol on the quality and membrane lipid metabolism of shiitake mushroom (Lentinus edodes) during storage.

The effect of oxyresveratrol on postharvest quality and membrane lipid metabolism of shiitake mushroom was investigated. The result exhibited that oxyresveratrol retarded browning, maintained firmness and alleviated occurrence of decay of shiitake mushroom..

Reishi · 2023 · Journal Article · International journal of biological macromolecules

Increased production and anti-senescence activity of exopolysaccharides in Ganoderma lingzhi by co-overexpression of β-1,3-glucan synthase and UDP-glucose pyrophosphorylase.

A β-1,3-glucan synthase gene (gls) was cloned and overexpressed in Ganoderma lingzhi. The content of intracellular polysaccharides (IPS) in G.