MycoData

Immune supportMetabolic healthGut & microbiome

Cordyceps · 2022 · Journal Article · International journal of molecular sciences

Extraction, Characterization, and Platelet Inhibitory Effects of Two Polysaccharides from the Cs-4 Fungus.

Cardiovascular diseases are associated with platelet hyperactivity, and downregulating platelet activation is one of the promising antithrombotic strategies. This study newly extracted two polysaccharides (purified exopolysaccharides, EPSp and purified intercellular exopolysaccharides, IPSp) from Cordyceps sinensis….

Immune supportMetabolic healthGut & microbiomeLiver support

Oyster Mushroom · 2022 · Journal Article · Frontiers in cellular and infection microbiology

In Vitro Hepatoprotective and Human Gut Microbiota Modulation of Polysaccharide-Peptides in Pleurotus citrinopileatus.

Pleurotus citrinopileatus, a golden oyster mushroom, is popular in Asia and has pharmacological functions. However, the effects of polysaccharide-peptides extracted from Pleurotus citrinopileatus and underlying mechanism on digestive systme have not yet been clarified..

Almond Mushroom · 2022 · Journal Article · Acta bio-medica: Atenei Parmensis

Is it a high time to focus on iron-mediated pathology initiated by COVID-induced inflammation?

A comment to paper published in the current issue by Duca et al (Acta Biomed 2022; Vol. 93, N.

OncologyImmune supportMetabolic health

Almond Mushroom · 2022 · Journal Article · RSC medicinal chemistry

Metabolic labelling of cancer cells with glycodendrimers stimulate immune-mediated cytotoxicity.

The recruitment of antibody naturally present in human blood stream at the surface of cancer cells have been proved a promising immunotherapeutic strategy to fight cancer..

Immune supportCognition & nervesRespiratory

Almond Mushroom · 2022 · Journal Article · Microbial pathogenesis

Non-steroidal anti-inflammatory drugs ketorolac and etodolac can augment the treatment against pneumococcal meningitis by targeting penicillin-binding proteins.

BACKGROUND: Streptococcus pneumoniae is the principal etiological agent of acute bacterial meningitis (ABM) which has fatal outcome in children and elderly. Due to poor blood-brain barrier (BBB) permeation, conventional β-lactam antibiotics fail to establish the requisite bactericidal concentration in central nervous….

Shiitake · 2022 · Journal Article · Alternative therapies in health and medicine

RBAC and Its Role with the Immune System.

CONTEXT: Rice Bran Arabinoxylan Compound (RBAC) is a trusted and proven immunomodulator made from a rice bran extract that has been enzymatically modified with an enzyme complex from the shiitake mushroom. OBJECTIVE: The study's primary objective was to identify the role of RBAC in supporting cancer therapies..

Almond Mushroom · 2021 · Journal Article · Cancers

A Spatial Quantitative Systems Pharmacology Platform spQSP-IO for Simulations of Tumor-Immune Interactions and Effects of Checkpoint Inhibitor Immunotherapy.

Quantitative systems pharmacology (QSP) models have become increasingly common in fundamental mechanistic studies and drug discovery in both academic and industrial environments..

Immune supportEnergy & fatigue

Chaga · 2021 · Research Article · Biomedica: revista del Instituto Nacional de Salud

Evaluation of UMELISA CHAGAS™ with the incorporation of new monomeric and chimeric peptides representative of different regions of Trypanosoma cruzi.

Introduction: Most people with Chagas disease develop specific antibodies against Trypanosoma cruzi. In early infection, IgM antibodies against T.

Immune supportEnergy & fatigueLiver supportSkin & hydration

Cordyceps · 2021 · Journal Article · Frontiers in bioscience (Landmark edition)

Hepatoprotective effect of genistein against dimethylnitrosamine-induced liver fibrosis in rats by regulating macrophage functional properties and inhibiting the JAK2/STAT3/SOCS3 signaling pathway.

BACKGROUND: Liver fibrosis is a dysregulated wound-healing process in response to diverse liver injuries, and an effective drug therapy is not yet available. Genistein, which is one of the most active natural flavonoids mainly derived from soybean products (e.g., Cordyceps sinensis mycelium), exhibits various….

Immune supportGut & microbiome

Cordyceps · 2021 · Journal Article · International journal of biological macromolecules

Modification and enhanced anti-inflammatory activity by Bifidobacterial fermentation of an exopolysaccharide from a medicinal fungus Cs-HK1.

The exopolysaccharide (EPS) from the mycelial fermentation of a medicinal fungus Cordyceps sinensis Cs-HK1 had shown significant anti-inflammatory activity previously, and EPS-LM was a highly active fraction with a relatively low molecular weight (MW) isolated from the Cs-HK1 EPS..

Immune supportCognition & nervesSkin & hydration

Almond Mushroom · 2021 · Journal Article · Simulation

Nested active learning for efficient model contextualization and parameterization: pathway to generating simulated populations using multi-scale computational models.

There is increasing interest in the use of mechanism-based multi-scale computational models (such as agent-based models (ABMs)) to generate simulated clinical populations in order to discover and evaluate potential diagnostic and therapeutic modalities..

Immune supportEnergy & fatigueSkin & hydration

Cordyceps · 2021 · Journal Article · Oxidative medicine and cellular longevity

Phototoxicity of Ultraviolet-A against the Whitefly Bemisia tabaci and Its Compatibility with an Entomopathogenic Fungus and Whitefly Parasitoid.

Ultraviolet (UV) radiation significantly affects insect life and, as a result, has been widely used to control different invertebrate pests. The current results demonstrate that when Bemisia tabaci first instar nymphs are exposed to UV-A light for 12, 24, 48, and 72 h, their developmental and biological parameters are….

Almond Mushroom · 2021 · Journal Article · International journal for numerical methods in biomedical engineering

Verification of an agent-based disease model of human Mycobacterium tuberculosis infection.

Agent-based models (ABMs) are a powerful class of computational models widely used to simulate complex phenomena in many different application areas. However, one of the most critical aspects, poorly investigated in the literature, regards an important step of the model credibility assessment: solution verification..

Immune supportMetabolic health

Cordyceps · 2019 · Data Paper · Data in brief

Dataset of the infrared spectrometry, gas chromatography-mass spectrometry analysis and nuclear magnetic resonance spectroscopy of the polysaccharides from C. militaris.

The data presented in this article describe characteristics of the polysaccharides, designated as CM1 and CMS, isolated from the fruiting body of C. militaris.

OncologyImmune supportMetabolic healthLiver support

King Oyster · 2008 · Research Article · Mycobiology

Anti-tumor Effects of Exo- and Endo-biopolymers Produced from Submerged Cultures of Three Different Mushrooms.

The anti-tumor effects of exo- (EX) and endo-biopolymers (EN) produced from submerged mycelial cultures of Ganoderma applanatum (GA), Collybia confluens (CC), and Pleurotus eryngii (PE) were studied using Sarcoma 180 bearing mice..

OncologyImmune supportGut & microbiomeRespiratory

Maitake · 2008 · Journal Article · Biological & pharmaceutical bulletin

Inhibitory effect of MD-Fraction on tumor metastasis: involvement of NK cell activation and suppression of intercellular adhesion molecule (ICAM)-1 expression in lung vascular endothelial cells.

The anti-metastatic activity of MD-Fraction extracted from the maitake mushroom (Grifola frondosa) was examined in an experimental murine model of lung metastasis..

Immune supportLiver supportRespiratory

Zhu Ling · 2001 · Systematic Review · The Cochrane database of systematic reviews

Chinese medicinal herbs for chronic hepatitis B.

BACKGROUND: Hepatitis B virus infection is a serious health problem worldwide. Traditional Chinese medicinal herbs have been widely used to treat chronic liver diseases, and many controlled trials have been done to investigate their efficacy..

Immune supportEnergy & fatigueGut & microbiome

Turkey Tail · 2023 · Research Support, Non U.S. Gov'T · Microbiology spectrum

A Laccase Gene Reporting System That Enables Genetic Manipulations in a Brown Rot Wood Decomposer Fungus Gloeophyllum trabeum.

Brown rot fungi are primary decomposers of wood and litter in northern forests. Relative to other microbes, these fungi have evolved distinct mechanisms that rapidly depolymerize and metabolize cellulose and hemicellulose without digesting the more recalcitrant lignin..

OncologyImmune supportMetabolic healthSkin & hydration

Oyster Mushroom · 2021 · Comparative Study · Anais da Academia Brasileira de Ciencias

Comparison of cell wall polysaccharides in Schizophyllum commune after changing phenotype by mutation.

The Agaricomycetes fungi produce various compounds with pharmaceutical, medicinal, cosmetic, environmental and biotechnological properties. In addition, some polysaccharides extracted from the fungal cell wall have antitumor and immunomodulatory actions..

Shiitake · 2021 · Comparative Study · Surgery today

Nutritional impact of active hexose-correlated compound for patients with resectable or borderline-resectable pancreatic cancer treated with neoadjuvant therapy.

Active hexose-correlated compound (AHCC) is a standardized extract from cultured Lentinula edodes mycelia, used as a potent biological response modifier in cancer treatment. We evaluated the nutritional effect of AHCC, given during neoadjuvant therapy, to patients with pancreatic ductal adenocarcinoma (PDAC)..

OncologyImmune supportMetabolic health

Chaga · 2014 · Research Support, Non U.S. Gov'T · Asian Pacific journal of cancer prevention: APJCP

Inotodiol inhabits proliferation and induces apoptosis through modulating expression of cyclinE, p27, bcl-2, and bax in human cervical cancer HeLa cells.

Inonotus obliquus is a medicinal mushroom that has been used as an effective agent to treat various diseases such as diabetes, tuberculosis and cancer. Inotodiol, an included triterpenoid shows significant anti-tumor effect.

Mesima · 2012 · Patent · journal metadata

COSMETIC COMPOSITION FOR IMPROVING SKIN COMPRISING HC-6 COMPLEX EXTRACTS

PURPOSE: A cosmetic composition containing phellinus linteus extract, Glycyrrhiza Radix extract, aloe vera gel, and Centella asiatica extract is provided to ensure anti-aging, skin whiteing, or anti-wrinkling..

Turkey Tail · 2012 · Patent · journal metadata

DRUG FOR TREATING TUMOR, ANTITUMOR AGENT, METHOD FOR TREATING TUMOR AND KIT FOR TREATING TUMOR

The purpose of the present invention is to provide a drug for treating tumor which is capable of exhibiting a therapeutic effect on non-responders, from among patients with gastric cancer, colorectal cancer and small cell lung cancer, said non-responders showing little response (sensitivity) to an antitumor agent….

Immune supportCognition & nervesEnergy & fatigue

Chaga · 2010 · Patent · journal metadata

Product for enhancing organic immunity and improving sleeping quality and preparation method thereof

The invention relates to a product for enhancing organic immunity and improving sleeping quality and a preparation method thereof, which belong to the field of functional health foods..

Immune supportLiver support

Niu-Chang-Chih · 2009 · Patent · journal metadata

Compositions for providing hepatoprotective effect

This invention relates to a composition for injection comprising a neutral polysaccharide of Antrodia camphorata having characteristics as follows: (a) appearance: colorless and shapeless powder, (b) pH: neutral, (c) molecular weight: 899.5-1670.5 kDa determined by HPLC as shown in (4), (d) rotatory power:….

Mesima · 2009 · Patent · journal metadata

Glossy ganoderma peanut beverage and preparation method thereof

A lucidum peanut drink and a preparation method thereof belong to the technical field of drink containing lucidum and peanut. The technical problem needed to be solved is to provide a lucidum peanut drink containing a plurality of nutrition components..

Maitake · 2009 · Patent · journal metadata

INDUCER FOR INDUCING A TH1 CELL-DOMINANT CONDITION FROM A TH2 CELL-DOMINANT CONDITION

Disclosed is an inducer that would enable the provision of products such as medical preparations, cosmetic products, foods, and beverages that can improve, treat, or prevent allergic disorders or other inflammatory diseases caused by a Th2 cell-dominant condition, by improving the balance between Th1 cells and Th2….

Enoki · 2009 · Patent · journal metadata

Preparation of gold needle mushroom polysaccharide

The invention relates to a method for preparing flammulina velutipes polysaccharide with simple operation and low equipment investment, which comprises the following process procedures: activating a slant strain, shaking culture of seeds, submerged fermentation in liquid, continuous fermentation, separation by an….

OncologyImmune supportLiver support

Mesima · 2009 · Patent · journal metadata

Yellow mulberry glossy ganoderma polyoses liquid and preparation method thereof

The present invention relates to polysaccharide solution of phellinus linteus and ganoderma lucidum, and a preparation method thereof, belonging to the technical field of health-care preparation containing raw materials. The polysaccharide solution contains a plurality of types of nutrients..

Mesima · 2008 · Patent · journal metadata

A NOVEL PHELLINUS STRAIN AND THE METHOD FOR ISOLATING beta-1,3 GLUCOMANNAN THEREFROM SHOWING IMMUNE ENHANCING ACTIVITY AND ANTITUMOR ACTIVITY

A beta-1,3 glucomannan polysaccharide isolated from a novel Phellinus strain is provided to increase the immunity and secure the anticancer effect, thereby being used for a pharmaceutical composition or a health functional food for preventing and treating cancers. A novel Phellinus strain has a sequence of SEQ ID: NO..

OncologyImmune supportCognition & nervesEnergy & fatigue

Mesima · 2008 · Patent · journal metadata

ANTIOXIDANT COMPOSITION CONTAINING HISPIDIN DERIVATIVES FROM THE CULTURE BROTH OF FUNGI PHELLINUS AND INONOTUS SPP

A composition containing hispidin derivatives isolated from the culture broth of fungi Phellinus and Inonotus spp. is provided to scavenge superoxide radical, ABTS(2,2'-azinobis-(3-ethylbenzothiazoline-6-sulphonic acid)) radical and DPPH(1,1-Diphenyl-2-Picrylhydrazyl) radical, so that the composition is useful for….

Maitake · 2008 · Patent · journal metadata

Applications of ash tree flowers polysaccharide for preparing preventing and controlling fowl virosis medicament

The invention discloses an application of Grifola frondosa polysaccharide when preparing the machine for preventing fowl virosis. The clinical study proves that the Grifola frondosa polysaccharide has good therapeutic efficacy to fowl virosis, more particularly gets rid of the clinical symptoms caused by virus….

Maitake · 2008 · Patent · journal metadata

Applications of ash tree flowers polysaccharide for preparing preventing and controlling pig virosis medicament

The invention relates to the use of polysaccharides of Grifola frondosa in preparing drugs for controlling viral diseases in pigs, particularly to the use for controlling porcine rotavirus enteritis, porcine epidemic diarrhea and porcine transmissible gastroenteritis..

Chaga · 2008 · Patent · journal metadata

Beverage made from edible fungus sporophore

The invention provides edible fungi drink which is made of edible fungi inonotus obliquus and manyzoned polypore and has the advantages of health caring function and eating convenience..

Chaga · 2008 · Patent · journal metadata

COMPOSITIONS FOR MAKEUP OR CLEANSING WHICH IS COMPOSED FROM HEMP-SEED-OIL AND METHOD FOR MANUFACTURING THE COMPOSITIONS

A composition is provided to perform various useful functions of moisturizing, sterilizing, enhancing immunity, and treating various skin diseases, thereby being used as a cosmetic or a washing product..

Immune supportLiver support

Niu-Chang-Chih · 2008 · Patent · journal metadata

COMPOSITIONS FOR PROVIDING HEPATOPROTECTIVE EFFECT

This invention relates to a composition for injection comprising a neutral polysaccharide of Antrodia camphorata having characteristics as follows: (a) appearance: colorless and shapeless powder, (b) pH: neutral, (c) molecular weight: 899.5~1670.5 kDa determined by HPLC as shown in (4), (d) rotatory power: (a) D….

Immune supportEnergy & fatigueLiver support

Chaga · 2007 · Patent · journal metadata

COMPOSITION CONTAINING EFFECTIVE INGREDIENT OF LIQUEFIED MEDICAL HERB EXTRACTS FOR HANGOVER REMOVAL AND MANUFACTURING METHOD OF THEREOF

A composition containing the extracts of liquefied medicinal herbs is provided to improve immunity function, remove reactive oxygen species and enhance liver function, thereby rapidly removing hangover and restoring fatigue caused by stresses rapidly..

Mesima · 2007 · Patent · journal metadata

PREPARATION METHOD FOR AGED SPROUTED-GARLIC

Provided is a method for preparing fermented sprouted red garlic to reduce the specific and stimulus smell of garlic itself and to increase the content of polyphenol and beta-glucan..

Zhu Ling · 2007 · Patent · journal metadata

Preparation method of detoxification tablet with toad and poria

The invention relates to a method for producing toad Siberian cocklebur toxicide, wherein the excretion of toad adenohypophysis and several components of toad have significant toxicide function and cancer release function..

Immune supportMetabolic health

Chaga · 2007 · Patent · journal metadata

THE METHOD FOR BREEDING A HIGH-FUNTIONAL FOWL

Provided are a method for breeding functional domestic fowls to improve the taste of meat or egg and the immunity, and the meat and egg of the fowls bred by the method..

Almond Mushroom · 2020 · Published Erratum · Breastfeeding medicine: the official journal of the Academy of Breastfeeding Medicine

Additional Correction to: ABM Clinical Protocol #29: Iron, Zinc, and Vitamin D Supplementation During Breastfeeding, by Sarah N. Taylor and The Academy of Breastfeeding Medicine. Breastfeed Med 2018;13(6):398-404. DOI: 10.1089/bfm.2018.29095.snt. (Breastfeed Med 2018;13(9):639. DOI: 10.1089/bfm.2018.29095.snt.correx).

Metadata-grounded summary: This published erratum indexes research on Agaricus blazei in Breastfeeding medicine: the official journal of the Academy of Breastfeeding Medicine in 2020. MycoData maps the paper to immune support based on its title, species context, article metadata, and study classification..

OncologyImmune supportLiver support

Zhu Ling · 2020 · Preprint · journal metadata

Polyporus polysaccharide regulates proliferation, apoptosis and migration of bladder cancer cells by polarizing macrophages to M1 subtype in tumor microenvironment

Background: Polyporus polysaccharide (PPS), an active ingredient of traditional Chinese medicinal Polyporus umbellatus, has multiple biological functions, such as anti-cancer, immune-regulating and hepatoprotective activities..

Turkey Tail · 2020 · Preprint · journal metadata

Tramesan Elicits Durum Wheat Defence Against the Septoria Leaf Blotch Complex

The Septoria Leaf Blotch Complex (SLBC), caused by the two ascomycetes Zymoseptoria tritici and Parastagonospora nodorum, can reduce global yearly yield of wheat by up to 50%. In the last decade in Italy, SLBC incidence has increased; notably, durum wheat has proven to be more susceptible than common wheat..

Shiitake · 2018 · Case Reports · The journal of allergy and clinical immunology. In practice

A Case of Flagellate Dermatitis After Ingestion of Shiitake Mushrooms.

Metadata-grounded summary: This case reports indexes research on Lentinula edodes in The journal of allergy and clinical immunology. In practice in 2018.

Shiitake · 2018 · Review · Journal of cancer research and clinical oncology

Lentinan as an immunotherapeutic for treating lung cancer: a review of 12 years clinical studies in China.

PURPOSE: Lentinan is a polysaccharide extracted from Shiitake mushrooms that have been used to improve general health for thousands of years in Asia. Lentinan injection is a clinically approved drug in several countries in Asia..

Turkey Tail · 2017 · Review · Frontiers in immunology

Immunomodulatory Properties of Coriolus versicolor: The Role of Polysaccharopeptide.

Traditional uses of herbal medicine have depended mostly on anecdotal evidence for much of history. The increasing application of scientific rigor to the study some of these traditional therapies in recent years has revealed potent bioactivity, notably demonstrated by the 2015 Nobel Prize for the discovery of an….

Immune supportSkin & hydrationRespiratory

Shiitake · 2017 · Case Reports · Annals of allergy, asthma & immunology: official publication of the American College of Allergy, Asthma, & Immunology

Shiitake mushroom-induced flagellate dermatitis.

Metadata-grounded summary: This case reports indexes research on Lentinula edodes in Annals of allergy, asthma & immunology: official publication of the American College of Allergy, Asthma, & Immunology in 2017. MycoData maps the paper to immune support, skin & hydration, respiratory based on its title, species context, article metadata, and study classification..

Immune supportGut & microbiome

Shiitake · 2015 · Journal Article · BUNSEKI KAGAKU

A Comparison of Dried Shiitake Mushroom in Log Cultivation and Mycelial Cultivation from Different Geographical Origins Using Stable Carbon and Nitrogen Isotope Analysis

Metadata-grounded summary: This journal article indexes research on Lentinula edodes in BUNSEKI KAGAKU in 2015. MycoData maps the paper to immune support, gut & microbiome based on its title, species context, article metadata, and study classification..