MycoData

Enoki · 2012 · Research Support, Non U.S. Gov'T · Transgenic research

Characterization of an immunomodulatory Der p 2-FIP-fve fusion protein produced in transformed rice suspension cell culture.

Der p 2, a major allergen of Dermatophagoides pteronyssinus mites, is one of the most clinically relevant allergens to allergic patients worldwide. FIP-fve protein (Fve) from the golden needle mushroom (Flammulina velutipes) is an immunomodulatory protein with potential Th1-skewed adjuvant properties..

Immune supportMetabolic health

Enoki · 2012 · Research Support, Non U.S. Gov'T · Molecules (Basel, Switzerland)

Chemical characteristics and antioxidant properties of crude water soluble polysaccharides from four common edible mushrooms.

Four crude water soluble polysaccharides, CABP, CAAP, CFVP and CLDP, were isolated from common edible mushrooms, including Agaricus bisporus, Auricularia auricula, Flammulina velutipes and Lentinus edodes, and their chemical characteristics and antioxidant properties were determined..

Enoki · 2012 · Research Support, Non U.S. Gov'T · Journal of agricultural and food chemistry

IFN-γ induction on carbohydrate binding module of fungal immunomodulatory protein in human peripheral mononuclear cells.

FIP-fve is a protein that is isolated from Flammulina velutipes. Its known immunomodulatory activities are elicitation of the production of type II interferon from human peripheral mononuclear cells (hPBMCs) and hemagglutination..

Niu-Chang-Chih · 2012 · Research Support, Non U.S. Gov'T · The American journal of Chinese medicine

Inhibition of Na(+)/K(+) -ATPase by antcins, unique steroid-like compounds in Antrodia camphorate.

The inhibition of Na(+)/K(+) -ATPase by versatile steroid-like compounds contributes to the putative therapeutic effects of many Chinese medicinal cardiac products via the same molecular mechanism triggered by cardiac glycosides..

Immune supportMetabolic healthGut & microbiomeRespiratory

Maitake · 2012 · Research Support, Non U.S. Gov'T · Glycobiology

Mannose-specific lectin from the mushroom Hygrophorus russula.

A lectin was purified from the mushroom Hygrophorus russula by affinity chromatography on a Sephadex G-50 column and BioAssist S cation exchange chromatography and designated H. russula lectin (HRL)..

Immune supportMetabolic health

Turkey Tail · 2012 · Research Support, Non U.S. Gov'T · Bioresource technology

Optimization of dilute acid-based pretreatment and application of laccase on apple pomace.

The present study was aimed to optimize acid-based pretreatment of apple pomace in relation to acid concentration, temperature and reaction time using response surface method with glucose as response variable. In addition, laccase (EC..

Immune supportEnergy & fatigueMetabolic health

Maitake · 2012 · Patent · journal metadata

PRODUCT OF FUNCTIONAL HEALTH FOOD THAT ENHANCES ORGAN IMMUNITY

A functional health food product that enhances organ immunity and controls diabetes comprises active ingredients and auxiliary material. The active ingredients consist of the following: 5 to 10 parts of cordyceps militaris extracts, 35 to 50 parts of grifola frondosa extracts, 20 to 30 parts of lentinan, 5 to 10 parts….

Snow Fungus · 2012 · Patent · journal metadata

SKIN WOUND DRESSING AND PREPARING METHOD THEREOF

A skin wound dressing is disclosed. The skin wound dressing comprises Tremella polysaccharide and alginate and is used to cover on a skin wound to accelerate wound healing.

Mesima · 2011 · Research Support, Non U.S. Gov'T · Nutrition and cancer

A heat-stable extract from Mucuna stimulates the differentiation of bone marrow cells into dendritic cells and induces apoptosis in cancer cells.

Pine cone extract is known to induce differentiation of human mononuclear cells into dendritic cells (DCs) and also to induce apoptosis in human cancer cells. In the present study, we screened edible plants that contain components with biological activities similar to or more potent than those of pine cone extract..

OncologyImmune support

Immune supportLiver support

Mesima · 2011 · Other · Evidence-based complementary and alternative medicine: eCAM

Analgesic effects and the mechanisms of anti-inflammation of hispolon in mice.

Hispolon, an active ingredient in the fungi Phellinus linteus was evaluated with analgesic and anti-inflammatory effects. Treatment of male ICR mice with hispolon (10 and 20 mg/kg) significantly inhibited the numbers of acetic acid-induced writhing response..

Niu-Chang-Chih · 2011 · Research Support, Non U.S. Gov'T · Free radical biology & medicine

Antroquinonol reduces oxidative stress by enhancing the Nrf2 signaling pathway and inhibits inflammation and sclerosis in focal segmental glomerulosclerosis mice.

Oxidative stress, inflammation, and fibrosis are involved in the development and progression of focal segmental glomerulosclerosis (FSGS), a common form of idiopathic nephrotic syndrome that represents a therapeutic challenge because it has a poor response to steroids..

Niu-Chang-Chih · 2011 · Research Support, Non U.S. Gov'T · Organic & biomolecular chemistry

First total synthesis of antrocamphin A and its analogs as anti-inflammatory and anti-platelet aggregation agents.

Naturally occurring antrocamphin A (1) is a potent anti-inflammatory compound from the edible fungus Antrodia camphorata (Taiwanofungus camphoratus), whose wild fruiting body is used as a valuable folk medicine in Taiwan. This study is the first total synthesis of antrocamphin A (1) and its analogs..

Snow Fungus · 2011 · Patent · journal metadata

FUNGUS POLYOSE COMPOSITION WITH IMMUNITY ENHANCING EFFECT AND APPLICATION THEREOF

The present invention relates to a compound fungus polyose with the effect of enhancing immunity. The compound is prepared with raw material as follows: Lentinus edodes 8~100, Poria cocos 15~100, Dictyophora indusiata 10~200, Tremella fuciformis 15~80, Paecilomyces hepiali mycelium 2~50..

Mesima · 2011 · Patent · journal metadata

MIXTURE EXTRACTS HAVING ANTI-OXIDATION ACTIVITY AND ANTI-INFLAMMATORY ACTIVITY AND COSMETIC COMPOSITION COMPRISING THE SAME

PURPOSE: A mixture extract of Carthamus tinctorius L., Triticum vulgare buds, Schizomepeta tenuifolia var. japonica, and Glycine soja is provided to ensure antioxidation and anti-inflammation and to relieve skin irritation..

Immune supportMetabolic health

Maitake · 2011 · Patent · journal metadata

UMAMI FOOD, AND METHOD FOR PRODUCING SAME

Provided is a food which takes on a rich umami flavor, and which is effective for the treatment and prevention of various immunological and inflammatory disorders, oxidative stress disorder, and metabolic syndrome. Also provided is a method for producing said food..

OncologyImmune supportMetabolic healthLiver support

Niu-Chang-Chih · 2010 · Research Support, Non U.S. Gov'T · Nutrition and cancer

Dietary effect of Antrodia Camphorate extracts on immune responses in WEHI-3 leukemia BALB/c mice.

Antrodia camphorata has been recognized to be a traditional Chinese medicine for abdominal pain, diarrhea, and to protect against hepatitis virus infection. Several ingredients derived from A.

Immune supportEnergy & fatigue

Maitake · 2010 · Evaluation Study · Biosensors & bioelectronics

Hydrophilic modification of polystyrene with hydrophobin for time-resolved immunofluorometric assay.

Herein we reported that a hydrophobin film was used as a solid support on the polystyrene surface for immobilizing antibodies in the time-resolved immunofluorometric assay (TR-IFMA)..

OncologyImmune supportRespiratory

Mesima · 2010 · Research Support, Non U.S. Gov'T · Journal of medical virology

Induction of cross-protective immunity against influenza A virus H5N1 by an intranasal vaccine with extracts of mushroom mycelia.

The identification of a safe and effective adjuvant that is able to enhance mucosal immune responses is necessary for the development of an efficient inactivated intranasal influenza vaccine..

Immune supportMetabolic healthGut & microbiomeRespiratory

Maitake · 2010 · Patent · journal metadata

Mushroom concentrated liquid and drink containing beta-glucan and preparation method thereof

The invention discloses mushroom concentrated liquid and drink containing beta-glucan, which is liquid type health-care drink prepared by mixing 5-50 percent of concentrated extract liquid of nine mushrooms of birch mushroom, phellinus linteus, ganoderma lucidum, grifola frondosa, hericium erinaceum, shiitake….

OncologyImmune supportSkin & hydrationRespiratory

Lion's Mane · 2010 · Patent · journal metadata

Transdermal infusion paste preparation for enhancing immunity and preparation method thereof

The invention provides a transdermal infusion paste preparation for enhancing immunity and a preparation method thereof and relates to a preparation for enhancing the immunity and a preparation method thereof..

Enoki · 2009 · Patent · journal metadata

Application of fungal immunomodulatory protein for inhibiting delta 5-desaturated enzyme

The invention provides a novel application of a fungi immunomodulatory protein in inhibiting delta5-desaturase, through which chronic or acute inflammatory reactions, inflammation symptoms or inflammatory diseases induced by concentration disorder of delta5-desaturase, arachidonic acid or inflammatory eicosanoids can….

OncologyImmune supportRespiratory

Enoki · 2009 · Research Support, Non U.S. Gov'T · Immunology

Coadministration of the fungal immunomodulatory protein FIP-Fve and a tumour-associated antigen enhanced antitumour immunity.

Fve is a fungal protein isolated from the golden needle mushroom Flammulina velutipes and has previously been reported to trigger immunological responses in both mouse and human lymphocytes..

Mesima · 2009 · Patent · journal metadata

COSMETIC COMPOSITION FOR PREVENTING OF KIN TROUBLE

A cosmetic composition for relieving the skin trouble is provided to improve the anti-inflammation effect and to enhance the safety to the skin. A cosmetic composition for relieving the skin trouble contains the fermentation extract of at least one selected from the group consisting of Lonicera japonica, Adenophora….

Mesima · 2009 · Research Support, Non U.S. Gov'T · Bioprocess and biosystems engineering

Effects of phytohormones on mycelial growth and exopolysaccharide biosynthesis of medicinal mushroom Phellinus [corrected] linteus.

Effects of phytohormones including indole-3-acetic acid (IAA), indole-3-butyric acid (IBA) and 1-naphthaleneacetic [corrected] acid (NAA) on mycelial growth of medicinal mushroom Phellinus linteus were investigated..

Zhu Ling · 2009 · Patent · journal metadata

EXTRACTION METHOD OF PROTEIN POLYSACCHARIDE USING EXTRACTION PROCESS OF HIGH HYDROSTATIC PRESSURE AND HYDROTHERMAL AND MUSHROOM PROCESSED FOODSTUFFS MANUFACTURING METHOD OF THE SAME

A method of extracting protein-polysaccharides using a high pressure hot water extraction technology and a method of producing mushroom processing food are provided to prevent a deterioration of bioactive substance and nutritive elements by the heat, and increase the extracting efficiency and bioactive substance..

Maitake · 2009 · Patent · journal metadata

Feed additive capable of enhancing production capacity and anti-disease capacities of animals

A feed additive capable of enhancing the production capacity and the anti-disease capacities of animals relates to the feeds which prevent diseases of animals, in particular to the feed additive capable of enhancing the production capacity and the anti-disease capacities of animals and a preparation method thereof..

Enoki · 2009 · Research Support, Non U.S. Gov'T · Journal of agricultural and food chemistry

FIP-fve stimulates interferon-gamma production via modulation of calcium release and PKC-alpha activation.

Fungal immunomodulatory protein, FIP-fve, has been isolated from Flammulina velutipes, and its immunomodulatory effects are believed to be associated with the enhanced activation of IFN-gamma-releasing Th1 cells..

OncologyImmune supportEnergy & fatigueMetabolic health

Lion's Mane · 2009 · Patent · journal metadata

Five-element health-preserving capsule

The invention provides a five-element health-preserving capsule, which adopts Chinese caterpillar fungus, Ganoderma lucidum, Hericium erinaceus, edible tree fungus and tea as raw materials, mixes the raw materials in proportioning, and then preparing the five-element health-preserving capsule after granulation,….

Immune supportCognition & nervesEnergy & fatigueMetabolic health

Lion's Mane · 2009 · Patent · journal metadata

Green bamboo health-care beverage and preparation method thereof

A green bamboo health-care drink and a preparation method thereof, characterized by comprising the following dry raw materials: 70-90 parts of green bamboo leaves, 4-15 parts of hericium erinaceus or dictyophora phalloidea, 5-10 parts of chrysanthemum or grass jelly, and appropriate amount of sugar and purified water..

Lion's Mane · 2009 · Patent · journal metadata

Health food with immunity reinforcement function

The invention discloses a health food with the function of enhancing immunity, which comprises the following active components in portion by weight: 3 to 50 portions of hericium erinaceus, 3 to 50 portions of flammulina velutipes, 3 to 50 portions of lentinus edodes, 3 to 50 portions of tuckahoe, 1 to 20 portions of….

Immune supportRespiratory

Chaga · 2009 · Patent · journal metadata

INHIBITOR OF REPRODUCTION OF HUMAN IMMUNODEFICIENCY VIRUS TYPE 1

FIELD: medicine. ^ SUBSTANCE: invention refers to pharmaceutical industry, particularly to inhibitor of reproduction of human immunodeficiency virus type 1.

Immune supportCognition & nerves

Maitake · 2009 · Research Support, Non U.S. Gov'T · Bioscience, biotechnology, and biochemistry

Involvement of Branched Units at Position 6 in the Reactivity of a Unique Variety of β-D-Glucan from Aureobasidium pullulans to Antibodies in Human Sera

We recently determined the structure of a unique type of 1,3-beta-D-glucan obtained from Aureobasidium pullulans (AP-FBG) and found that it reacted with the antibodies in human sera..

Lion's Mane · 2009 · Patent · journal metadata

Medicine for treating cancer

The invention provides a medicine for treating cancer. The medicine is made from lentinus edodes polysaccharide, hericium erinaceus polysaccharides, glutamic acid, aspartic acid, tuckahoe, soybean oligosaccharide and fructo-oligosaccharide..

OncologyImmune support

OncologyImmune supportEnergy & fatigueGut & microbiome

Maitake · 2009 · Abstract · Molecular & cellular proteomics: MCP

Poster Session A

A.1 Labeling of Peptide Fragmented Mass Spectra in Proteomic Studies B. Gerrits1, C.

Lion's Mane · 2009 · Patent · journal metadata

Process for simultaneous extraction and purification of fine chemicals from spent mushroom compost, mushroom stems and partially degraded mushroom fruiting bodies

The aim of this process consists of simultaneous extraction and purification of fine chemicals (i.e enzymes, protein - bound polysaccharides, lectins, alkaloids, antibiotics and terpenes) from spent mushroom compost, mushroom stems or partially degraded mushroom fruiting bodies..

Immune supportEnergy & fatigueMetabolic healthLiver support

Snow Fungus · 2009 · Comparative Study · Journal of microbiology and biotechnology

Proteomic analysis in ob/ob mice before and after hypoglycemic polysaccharide treatments.

In an attempt to discover novel biomarker proteins in type 2 diabetes prognosis, we investigated the influence of hypoglycemic extracellular polysaccharides (EPS) obtained from the macrofungus Tremella fuciformis on the differential levels of plasma proteins in ob/ob mice using two-dimensional gel electrophoresis….

Enoki · 2009 · Patent · journal metadata

Use of golden mushroom in animal production

The invention relates to an application of flammulina velutipe powders in animal production, which belongs to the field of microbe making. The flammulina velutiper powders adopt the following fermentation medium formula with Flammulina velutipes (Fr.)Sing.As5.632 as the production strains to carry out the liquid….

Immune supportLiver support

Lion's Mane · 2008 · Patent · journal metadata

A sobering-up agent

The invention relates to a Chinese drug health product, in particular to a Chinese drug antialcoholic health product. The antialcoholic drug of the invention uses the extractive of coriolus versicolor polysaccharide as the main raw material, and also the extractive of hericium erinaceus polysaccharide and the….

Mesima · 2008 · Patent · journal metadata

Biologic compound amylose nutrient fluid with high efficiency and preparing method thereof

The invention relates to a preparation method of a biological composite polysaccharide efficient nutrient solution. The invention comprises the steps of selecting a strain, preparing a nutrient, culturing a liquid spawn, generating a mycelium in a fermentor, filtrating the fermentation broth and generating the….

Immune supportGut & microbiomeSkin & hydration

Mesima · 2008 · Patent · journal metadata

COSMETIC COMPOSITION FOR PREVENTING OF KIN TROUBLE

A cosmetic composition comprising a fermented extract of medicinal stuff is provided to show skin trouble alleviating effect due to anti-inflammatory effect and be safe to skin..

Immune supportEnergy & fatigueGut & microbiome

Mesima · 2008 · Research Support, Non U.S. Gov'T · Phytotherapy research: PTR

Fermented guava leaf extract inhibits LPS-induced COX-2 and iNOS expression in Mouse macrophage cells by inhibition of transcription factor NF-kappaB.

The goal of this study was to elucidate the antiinflammatory activities of Psidium guajava L. (guava) leaf.

Enoki · 2008 · Patent · journal metadata

Injection for reducing drug dependency and preparation thereof

An injection for reducing drug dependence consists of tetrodotoxin (TTX) separated from puffer fish and flammulina velutipes polysaccharide, the TTX and polysaccharide are mixed according to the prescribed ratio and prepared with sterile water, after filtration sterilization with a microporous membrane, nitrogen….

Immune supportGut & microbiome

Lion's Mane · 2008 · Patent · journal metadata

Medicine for treating gastritis and gastrointestinal ulcer

The present invention relates to a medicine for effectively curing the diseases of gastritis and gastric ulcer with obvious therapeutic effect. Said medicine is made up by using (by weight portion) 2-3 portions of swine thymus protein and 5-7 portions of hericium erinaceus polysaccharide extract through a certain….

Maitake · 2008 · Patent · journal metadata

THE FUNCTIONAL BREAD COMPOSITION AND ITS PRODUCING METHOD ADDED CAULIFLOWER MUSHROOM

A method of manufacturing a functional bread composition by addition of Sparassis crispa extract, dietary fiber of Sparassis crispa and mushroom powder to wheat flour is provided to obtain a bread composition with the efficacy of Sparassis crispa and mushrooms such as immune activity..

OncologyImmune supportLiver support

Enoki · 2007 · Patent · journal metadata

Anti-tumor application of orally administrated FIP-fve on antitumor application

The anti-tumor effect of FIP-fve, an immunomodulatory protein derived from Flammulina velutipes, was well demonstrated. Oral administration of FIP-fve (200 mg protein/mouse) every other day significantly increased the survival of BNL 1MEA.7R.1 hepatoma-bearing mice and inhibits the growth of hepatoma (p < 0.05)..

Immune supportCognition & nervesEnergy & fatigue

Niu-Chang-Chih · 2007 · Comparative Study · Journal of ethnopharmacology

Comparative anti-inflammatory characterization of wild fruiting body, liquid-state fermentation, and solid-state culture of Taiwanofungus camphoratus in microglia and the mechanism of its action.

Taiwanofungus camphoratus (syn. Antrodia camphorata), a medicinal mushroom in Taiwan, is reputed to provide several therapeutic benefits, but the wild fruiting body is very rare..

Mesima · 2007 · Patent · journal metadata

COMPOSITION CONTAINING ATO-CONTROL SYSTEM FOR ANTI-ALLERGY AND PREVENTION EFFECTS OF SKIN

A composition comprising extracts of medicinal herbs is provided to alleviate itching by inhibiting histamine release, inhibit inflammation in the skin, strengthen skin immunity, and moisturize the skin by promoting production of hyaluronic acid, thereby alleviating and preventing skin allergy such as atopic….

Enoki · 2007 · Patent · journal metadata

Dry type, semi dry type fermentative tuckahoe wine, and preparation method

This invention provides a dry and semi-dry Poria cocos fermented wine, which is a bred wine produced by fermenting Poria cocos strain liquid to obtain fermentation liquid, and then fermenting with ethanol..

Mesima · 2007 · Patent · journal metadata

MANUFACTURING METHOD AND COSMETIC COMPOSITIONS PREVENTING SKIN AGING

Cosmetic compositions are provided to promote proliferation of a cell and biosynthesis of collagen, inhibit oxidation and inflammation, and moisturize the skin without skin irritation by using nontoxic medicinal herbs, thereby preventing skin aging and improving atopic dermatitis..