MycoData

Abstract To obtain Ganoderma lucidum triterpenoids (GLTs) with high antioxidant capacity, a new method of enzymatic extraction using pectinase and cellulase enzymes was developed and tested..

Energy & fatigue

High relevance

Cordyceps · 2023 · Preprint · journal metadata

Overexpression of glycosyltransferase genes enhance the production of extracellular polysaccharides in Cordyceps militaris

This study aimed to increase the production of extracellular polysaccharides in Cordyceps militaris by overexpressing polysaccharide transferase genes, including alpha-1,2-mannosyltransferase ( Kre5 ), alpha-1,3-mannosyltransferase ( CMT1 ), alpha-1,6-mannosyltransferase subunit ( A16 ), and….

Immune support

High relevance

King Oyster · 2023 · Preprint · journal metadata

The discovery of ergothioneine biosynthesis genes from Pleurotus eryngii and its combinatorial expression in yeast

Ergothioneine (EGT) is a natural amino acid derived from histidine, which has many active functions such as anti-oxidation, anti-inflammation, anti-cancer and prevention of neurodegenerative diseases. Pleurotus eryngii is a delicious edible fungus with high EGT content..

OncologyImmune supportCognition & nerves

High relevance

Cordyceps · 2023 · Preprint · journal metadata

Therapeutic potential of Cordyceps militaris mushroom against SARS-CoV-2: Virtual screening against Mpro and in vitro validation

Pathogenic coronavirus, including COVID-19, threatens human health, and there are strong demands for efficient therapeutics. Cordyceps militaris is a medicinal mushroom that has long been used for immune enhancement, anticancer, and antiviral effects.

OncologyImmune supportRespiratory

High relevance

Reishi · 2023 · Preprint · journal metadata

Triterpenoid HPLC Fingerprint of the Mycelia of Ganoderma lucidum (lingzhi)

(1) Background: ganoderic acids (GAs) are specific triterpenes of Ganoderma lucidum. The HPLC fingerprint profile of GAs of the fruiting body has been well-known, but the mycelial fingerprinting remains unclear.

High relevance

Reishi · 2023 · Preprint · journal metadata

Use of Ganoderma lucidum Grown on Agricultural Waste to Remove Antibiotics from Water

Abstract Antibiotic-rich effluents from farming and medical applications into waterways pose a serious risk for antibiotic drug resistance, promoting a need for effective strategies of removal from the food chain and the environment..

High relevance

Oyster Mushroom · 2023 · Preprint · journal metadata

Utilization of Disposable Face Masks as Substrate for Pleurotus Ostreatus Mushroom Production

Utilization of disposable face mask (FM) as carbon source for the cultivation of Pleurotus ostreatus mushroom was investigated in the attempt to reduce plastic build up in the environment due to its disposal..

High relevance

Oyster Mushroom · 2023 · Preprint · journal metadata

Utilization of Disposable Face Masks as Substrate for Pleurotus Ostreatus Mushroom Production

High relevance

Cordyceps · 2022 · Preprint · journal metadata

Acute kidney injury related to Cordyceps militaris: A case series

Abstract Background Cordyceps sinensis is an ancient traditional Chinese medicine, known as caterpillar fungus, that is one of the most commonly used ingredients to treat people with chronic kidney disease or to facilitate post-kidney transplant health..

Energy & fatigue

High relevance

Cordyceps · 2022 · Preprint · journal metadata

Altered GC- and AT-biased genotypes of Ophiocordyceps sinensis in the stromal fertile portions and ascospores of natural Cordyceps sinensis

Objective To examine multiple genotypes of Ophiocordyceps sinensis in a semi-quantitative manner in the stromal fertile portion (SFP) densely covered with numerous ascocarps and ascospores of natural Cordyceps sinensis and to outline the dynamic alterations of the coexisting O..

High relevance

Oyster Mushroom · 2022 · Preprint · journal metadata

Biotransformation of standard antibiotics by Pleurotus ostreatus mushroom and in vitro antibacterial activity of resulted metabolites

Background: Research and development of the new antibacterial agents are among the strategized measures to combat antimicrobial resistance (AMR). In the recent decades, biotransformation has been demonstrated as an alternative and effective approach for scavenging the new molecules..

High relevance

Shiitake · 2022 · Preprint · journal metadata

Combining UV-irradiation and alkaline deacetylation to obtain vitamin D- and chitosan-enriched fractions from shiitake mushrooms (Lentinula edodes)

Shiitake mushrooms ( Lentinula edodes ) contain compounds with hypocholesterolemic and immune-modulatory activities such as ergosterol and chitin that can be partially transformed into vitamin D and chitosan to yield extracts with enhanced bioactivities..

Immune supportMetabolic health

High relevance

Cordyceps · 2022 · Preprint · journal metadata

Differential coexistence of multiple genotypes of Ophiocordyceps sinensis in the stromata, ascocarps and ascospores of natural Cordyceps sinensis

Objective To examine the differential occurrence of Ophiocordyceps sinensis genotypes in the stroma, stromal fertile portion (SFP) densely covered with numerous ascocarps, and ascospores of natural Cordyceps sinensis. Methods Immature and mature C.

High relevance

Enoki · 2022 · Preprint · journal metadata

Effect of Mushroom Root Fermentation Broth on the Umami Taste and Nutrients of Flammulina velutipes

As one of the most appealing edible mushrooms, the quality of Flammulina velutipes can be affected by the cultivation substrate, which has an impact on the mushroom umami taste and nutrients. In our study, the effect of mushroom root fermentation broth (MRFB) based substrate on umami taste and nutrients of F..

High relevance

Lion's Mane · 2022 · Preprint · journal metadata

Effects of Polysaccharide from Hericium Erinaceus on Diarrhea Rats Induced by Lincomycin Hydrochloride: A Potential Treatment for Gut Microbiota Dysbiosis

Abstract In China, the fungus Hericium erinaceus is known as a healthy food crop which possesses digestive tract protection functionality. This research was focus on the effects of polysaccharides extracted from Hericium erinaceus (WHP) on rats with diarrhea induced by antibiotic, specifically on the shifts of gut….

Immune supportMetabolic healthGut & microbiome

High relevance

Shiitake · 2022 · Preprint · journal metadata

Effects of supplementation with Shiitake powder, Lentinula edodes, on anti-oxidative activities and energy/ lipid metabolism in healthy dogs

Abstract Obesity is the number one health problem pets face. Effective food and supplement should be developed to improve anti-oxidative activities and energy /lipid metabolism in obese animals..

Energy & fatigueMetabolic healthLiver support

High relevance

Cordyceps · 2022 · Preprint · journal metadata

Enhanced fruiting body production and bioactive phytochemicals from white Cordyceps militaris by blending Cordyceps militaris and using cold plasma jet

The impact of cold plasma jet (CPJ) on fruiting body production and bioactive phytochemicals in white Cordyceps militaris blended with Cordyceps militaris (blended C. militaris ) cultured on solid media was evaluated.

Energy & fatigue

High relevance

King Oyster · 2022 · Preprint · journal metadata

Enhancement of hyphae growth and medium optimization by Pleurotus eryngii-3 under submerged fermentation

Abstract There were a variety of amino acids and polysaccharides in Pleurotus eryngii contained that could improve human immunity and prevent cancer. In this paper, the medium was screened and carton and nitrogen sources were screened and optimized as 40 g/L corn flour and soybean meal by P.

OncologyImmune support

High relevance

King Oyster · 2022 · Preprint · journal metadata

Evaluation of the best time for spawning of Pleurotus eryngii mushroom to standardize the cultivation technology in Rajasthan, India

The aim behind this experiment was to know the suitability of months that gives better Biological efficiency and its sustainability with respect to yield. This research work was accomplished at the project of AICRP on medicinal mushroom unit in Department of Plant Pathology, Rajasthan College of Agriculture, Udaipur….

High relevance

Reishi · 2022 · Preprint · journal metadata

Ganoderma lucidum Methanolic Extraction as a Potent Phytoconstituent: Characterization, in-vitro Antimicrobial and Cytotoxic Activity

Background: Ganoderma lucidum has attracted tremendous attention due to its exceptional antimicrobial and anticancer properties that can be delicately tuned by controlling the initial extraction content and concentration..

OncologyEnergy & fatigue

High relevance

Cordyceps · 2022 · Preprint · journal metadata

Genetic and phylogenetic features of the repetitive ITS copies in the Hirsutella sinensis genome and the genomically independent AT-biased Ophiocordyceps sinensis genotypes

It has been hypothesized that AT-biased genotypes of Ophiocordyceps sinensis are generated through repeat-induced point mutation (RIP) and coexist as permanently nonfunctional internal transcribed spacer (ITS) pseudogenes in the genome of Hirsutella sinensis (GC-biased Genotype #1 of O. sinensis )..

Gut & microbiome

High relevance

Shiitake · 2022 · Preprint · journal metadata

Genome-wide identification of small GTPase gene family members in Lentinula edodes and their expression profiling under adversity stress

Background: Small GTPase superfamily is a small molecular switch involved inmultiple biological processes of eukaryotes. The main functions of GTPases in fungi include morphogenesis, secondary metabolism, vesicle trafficking, stressresponse, and virulence..

High relevance

King Oyster · 2022 · Preprint · journal metadata

Identification of s9ap Used as an Endogenous Reference Gene in Qualitative and Real-Time Quantitative PCR Detection of Pleurotus eryngii

Abstract Pleurotus eryngii is a kind of edible fungi with good quality, and it is popular among consumers. At present, some adulterated wild edible fungi are available in the market.

High relevance

King Oyster · 2022 · Preprint · journal metadata

Influence of different drying methods on drying characteristics, three- dimensional appearance, physicochemical property and microstructure of Pleurotus eryngii

This study investigated the effects of different drying methods, including hot air drying (HAD ), infrared drying (ID), and microwave drying (MD), on the drying characteristics, three-dimensional (3D) appearance, color, total polysaccharide content (TPC), antioxidant activity and microstructure of Pleurotus eryngii….

Immune support

High relevance

Oyster Mushroom · 2022 · Preprint · journal metadata

Polyethylene Terephthalate (PET) Biodegradation by Pleurotus ostreatus and Pleurotus pulmonarius

Abstract Essential properties of Polyethylene terephthalate (PET) such as lightness, high transparency, high mechanical strength, good moisture barrier, high heat resistance, and relatively low cost make it a suitable material for the packaging of natural mineral and soft drink bottles..

High relevance

King Oyster · 2022 · Preprint · journal metadata

Production performance and rumen bacterial community structure of Hu sheep fed fermented spent mushroom substrate from Pleurotus eryngii

This study aimed to compare the slaughter performance, meat quality and rumen bacterial community structure of Hu sheep by adding raw materials( RL0), 0 (RL1), 15% (RL2), 30% (RL3) and 45% (RL4) fermented spent mushroom substrate from Pleurotus eryngii to the basal diet..

Energy & fatigue

High relevance

Shiitake · 2022 · Preprint · journal metadata

Regulation of Key Enzymes in Lentinula Edodes Mycelium Culture by Chitosan

Abstract Chitosan is a plant growth regulator. Since it has an important function, it may also play a similar role in the growth of fungi.

High relevance

Reishi · 2022 · Preprint · journal metadata

Use of Ganoderma lucidum grown on agricultural waste to remove antibiotics from water

Antibiotic effluents from farming and medical applications into waterways pose serious risks for antibiotic drug resistance, promoting a need for effective strategies of removal from the environment. This experiment uses a novel mycoremediation approach to remove antibiotic contamination in synthetic wastewater..

High relevance

Chaga · 2021 · Preprint · journal metadata

Characterization and Anticancer Effects of Folate Targeted Inotodiol Liposome From Inonotus Obliquus (Chaga Mushroom)

Abstract Inotodiol, one tetracyclic triterpenoid isolated from inonotus obliquus (Chaga mushroom) possess excellent anticancer, antioxidant and anti-inflammatory activities, however it has not been applied to medical use due to its low solubility and low bioavailability..

OncologyImmune supportLiver support

High relevance

Chaga · 2021 · Preprint · journal metadata

Convergent evolution of mevalonate pathway in Inonotus obliquus and Betula pendula

Inonotus obliquus, Chaga mushroom, is a fungal species from Hymenochaetaceae family ( Basidiomycota ) which has been widely used for traditional medicine in Europe and Asia. Here, chaga genome was sequenced using Pacbio sequencing into a 50.7Mbp assembly consisting of 301 primary contigs with an N50 value of 375 kbp..

High relevance

Cordyceps · 2021 · Preprint · journal metadata

Cordyceps Militaris Carotenoids Protect ARPE-19 Cells From Oxidative Stress Damage Induced By Hydrogen Peroxide

A retinal disorder known as age-related macular degeneration (AMD) can be very damaging, which may result in vision loss. Cordyceps militaris has antioxidant, anti-inflammatory, anticancer activity and immunomodulatory functions..

OncologyImmune supportEnergy & fatigue

High relevance

Oyster Mushroom · 2021 · Preprint · journal metadata

Cultivation of mycelium of the edible fungus Pleurotus ostreatus (oyster mushroom) with the use of wet sparging grain, the waste of the brewing industry.

Wet sparging grain, a waste product of brewery, was shown to be successfully utilized as a supplement to the nutrient media and substrates for both isolation of the vegetative mycelium of the Pleurotus ostreatus mushroom, as well as for its further recovery and growing the carposomes..

High relevance

Cordyceps · 2021 · Preprint · journal metadata

Identification and functional analysis of bacteria in sclerotia of Cordyceps militaris

Background: Cordyceps militaris is a fungus that parasitizes insects. Compounds from C.

High relevance

Oyster Mushroom · 2021 · Preprint · journal metadata

In-silico Study Of Oyster Mushroom (Pleurotus Ostreatus ) Targeting PARP Protein (4UND)

Oyster mushroom( Pleurotus ostreatus) is belong to the group of healthy foods, as they contain high levels of proteins, vitamins and different classes of compounds, it is discovered that oyster mushrooms could play a key role in maintaining good health..

OncologyImmune supportEnergy & fatigueMetabolic health

High relevance

Oyster Mushroom · 2021 · Preprint · journal metadata

Morphological and Molecular Identification of Oyster Mushroom [Pleurotus Ostreatus (Jacq.) P. Kumm]

Abstract Oyster mushroom ( Pleurotus ostreatus ) is fleshy, edible fungi and used throughout the world. Among the most well-known species of mushrooms, Pleurotus sp.

High relevance

Cordyceps · 2021 · Preprint · journal metadata

Potential of Topical Microemulsion Serum Formulations to Enhance In Vitro and Clinical Anti-Skin Wrinkle Benefits of Cordyceps Militaris Extracts

This research is the first to investigate the anti-skin wrinkle properties of Cordyceps mili-taris extracts both in vitro and in vivo. Anti-skin wrinkle activities of C.

Skin & hydration

High relevance

Oyster Mushroom · 2021 · Preprint · journal metadata

Prehispanic Foods Oyster Mushroom (Pleurotus ostreatus), Nopal (Opuntia ficus-indica) and Amaranth (Amaranthus sp.) as New Alternative Ingredients for Developing Functional Cookies

Oyster mushroom (Pleurotus ostreatus), nopal (Opuntia ficus-indica) and amaranth (Amaranthus spp.) are pre-hispanic foods widely consumed in Mexico. However, there are no standard products developed with these ingredients as functional cookies..

High relevance

Almond Mushroom · 2021 · Preprint · journal metadata

Subcritical Water Extracts from Agaricus blazei Murrill's Mycelium Inhibits the Expression of Immune Checkpoint Molecules and Axl receptor

Agaricus blazei Murrill or Himematsutake is an edible and medicinal mushroom. Agaricus blazei Murrill's fruiting body extracts have anticancer properties, although the mechanism is unknown..

OncologyImmune supportRespiratory

High relevance

Chaga · 2021 · Preprint · journal metadata

The Influence of pH and Temperature on Water as a Pressurized Fluid in the Extraction of Bioactive Myconutrients from Chaga Mushroom (Inonotus obliquus)

Mushrooms have long rich history in folk medicine, traditional and functional foods due to high content of dietary myco-nutrients. Currently, there is increased interest in finding appropriate food-grade green ex-traction systems capable of extracting these bioactive compounds from dietary mushrooms for applica-tions….

Energy & fatigue

High relevance

Cordyceps · 2021 · Preprint · journal metadata

Transcriptome Analysis of Ophiocordyceps Sinensis Under Low-Temperature Treatment

Abstract This study aims to investigate the effect of low temperature on the gene expression in Ophiocordyceps Sinensis. To set up the experiments, two groups of Ophiocordyceps Sinensis were grown at 4°C and 18°C, respectively, for 60 days..

OncologyEnergy & fatigueMetabolic health

High relevance

Cordyceps · 2026 · Research Support, Non U.S. Gov'T · Bioorganic chemistry

Biotransformation-derived metabolites from Astragalus membranaceus and Cordyceps militaris alleviate hyperuricemia via multi-target regulation.

Hyperuricemia is a common metabolic disorder, and current pharmacological treatments are often associated with adverse effects. This study evaluated the anti-hyperuricemic activity of an ethanol extract obtained from bidirectional solid-state fermentation of Astragalus membranaceus and Cordyceps militaris (AMC-BFE) in….

Metabolic healthGut & microbiomeLiver support

High relevance

Lion's Mane · 2026 · Comparative Study · International journal of medicinal mushrooms

Comparative Analysis of Extraction Techniques for Phenolics and Polysaccharides from Lion's Mane Medicinal Mushroom Hericium erinaceus (Agaricomycetes): Optimization and Yield Evaluation.

Hericium erinaceus is widely recognized for its culinary and medicinal properties. This study evaluates various extraction techniques to optimize total phenolic and polysaccharide fractions in H.

Immune support

High relevance

Cordyceps · 2026 · Research Support, Non U.S. Gov'T · Molecular nutrition & food research

Cordycepin-Enriched Cordyceps militaris Extract ARA815 Induces Ferroptosis in Lung Cancer Cells In Vivo and In Vitro.

Cordyceps militaris, a traditional medicinal fungus and a promising food supplement, has demonstrated anticancer potential, yet its underlying mechanisms and in vivo efficacy remain poorly defined. Previously, we developed an optimized extraction and preparation protocol to enrich the bioactive content of C..

OncologyEnergy & fatigueRespiratory

High relevance

Shiitake · 2026 · Research Support, Non U.S. Gov'T · G3 (Bethesda, Md.)

Identification of regulatory candidate genes for Lentinula edodes pileus development based on transcriptome analysis.

The pileus serves as a primary determinant of market grade and commercial value in Lentinula edodes. To elucidate the molecular mechanisms governing pileus development, we conducted comparative transcriptome analysis via RNA sequencing across 3 distinct developmental stages: Early button stage, Young fruiting body….

High relevance

Maitake · 2025 · Research Support, Non U.S. Gov'T · Molecular nutrition & food research

Attenuative Effect of Grifola frondosa (Maitake Mushroom) on Severe DSS-Induced Colitis in Vitamin D-Deficient Mice.

Vitamin D deficiency, which has been a global health issue for decades, is involved in gut health and diseases. We examined the health benefits of Grifola frondosa (maitake mushroom), a potent dietary source of fungal vitamin D (D2), on DSS-induced colitis in vitamin D-deficient mice..

Immune supportGut & microbiome

High relevance

Cordyceps · 2025 · Comparative Study · Food research international (Ottawa, Ont.)

Comparative analysis of nutritional and flavor compound alterations in Cordyceps militaris juice fermented by single or mixed Lactobacillus strains.

Cordyceps militaris (CM) is a precious edible and medicinal mushroom known for its bioactive components, which can potentially be enhanced through microbial fermentation..

Gut & microbiome

High relevance

Chaga · 2025 · Comparative Study · International journal of molecular sciences

Comparative Study of Chaga (Inonotus obliquus) Dietary Supplements Using Complementary Analytical Techniques.

Chaga (Inonotus obliquus) is an increasingly used natural product in botanical dietary supplements, valued for its bioactive compounds. However, inconsistent standardized analytical methods raise concerns over product authenticity, mislabeling, and quality control..

Immune supportEnergy & fatigueSkin & hydration

High relevance

Shiitake · 2025 · Comparative Study · Food chemistry

Comparison between intense pulsed light and continuous ultraviolet treatment processes for enhancing the vitamin D2 content of shiitake mushroom (Lentinula edodes) powder.

Shiitake mushrooms (Lentinula edodes) are a rich source of ergosterol, which can be converted into vitamin D2, a valuable nutrient for human health. This study evaluated the enhancement of vitamin D2 in shiitake-mushroom powders using intense pulsed light (IPL)..

Skin & hydration

High relevance

Cordyceps · 2025 · Comparative Study · Chemistry & biodiversity

Enhanced Antioxidant and Anti-inflammatory Properties of Albino Cordyceps militaris: A Comparative Study With Wild-type Strain.

Cordyceps militaris is a medicinal fungus known for its immunomodulatory effects. This study compared the antioxidant and anti-inflammatory activities of an albino strain (C.

Immune support

High relevance

Oyster Mushroom · 2025 · Research Support, Non U.S. Gov'T · Applied and environmental microbiology

Establishing microbial communities to promote the growth of Pleurotus ostreatus through a top-down approach is hindered by the dominance of antagonistic interactions.

Few attempts have been made to examine the diversity and functions that characterize microbial communities compatible with and beneficial to the biotechnologically relevant mushroom Pleurotus ostreatus..

Energy & fatigueGut & microbiome