MycoData

Enoki · 2006 · Journal Article · Mycologia

An agglutinin with mitogenic and antiproliferative activities from the mushroom Flammulina velutipes.

A hemagglutinin with a molecular mass of 12 kDa was isolated from the fruiting bodies of the mushroom Flammulina velutipes. Its molecular mass is similar to that of the fungal immunomodulatory protein isolated from F..

Mesima · 2006 · Research Article · Mycobiology

Antitumor and Antioxidant Activities of the Extracts from Fruiting Body of Phellinus linteus.

Fruiting bodies of Phellinus linteus were extracted by hot water and alkali methods. Sugar contents of PL-H (hot water extract) and PL-A (alkali water extract) were 81.1%, 37.4% and protein contents were 6.2%, 21.8%, respectively..

Mesima · 2006 · Journal Article · Immunopharmacology and immunotoxicology

Effects of oral administration of Phellinus linteus on the production of Th1- and Th2-type cytokines in mice.

The mushroom Phellinus linteus (PL) has been shown to have antitumor and immunostimulatory effects. We hypothesized that the hot water extract of PL (WEPL) exerts its significant immunostimulatory effect by inducing production of the Th1-derived cytokine interferon-gamma (IFN-gamma) by T lymphocytes..

OncologyImmune supportRespiratory

Mesima · 2006 · Research Article · Mycobiology

Mycelial Extract of Phellinus linteus Induces Cell Death in A549 Lung Cancer Cells and Elevation of Nitric Oxide in Raw 264.7 Macrophage Cells.

In the present study, in order to investigate the anti-proliferative phenomenon of PLME, the effects of mycelial extract of Phellinus linteus (PLME) on the growth of human lung carcinoma cell line A549 was examined..

Maitake · 2006 · Journal Article · International journal of biological macromolecules

Preparation of a chemically sulfated polysaccharide derived from Grifola frondosa and its potential biological activities.

This report describes the preparation, characterization and potential biological activities of a chemically sulfated polysaccharide (S-GAP-P), which was derived from water-insoluble polysaccharide of Grifola frondosa mycelia..

Mesima · 2006 · Journal Article · World journal of microbiology & biotechnology

Quantitative response of cell growth and polysaccharide biosynthesis by the medicinal mushroom Phellinus linteus to NaCl in the medium

The effect of NaCl on cell growth and polysaccharide biosynthesis in the medicinal mushroom Phellinus linteus was studied. With the increase of NaCl concentration between 1 g/l and 7 g/l in the culture medium, the cell growth and intracellular polysaccharide (IPS) accumulation were decreased; extracellular….

Lion's Mane · 2006 · Journal Article · Carbohydrate research

Structural elucidation of a novel fucogalactan that contains 3-O-methyl rhamnose isolated from the fruiting bodies of the fungus, Hericium erinaceus.

A new heteropolysaccharide, HEPF3, was isolated from the fruiting bodies of Hericium erinaceus. HEPF3 has a molecular weight of 1.9 x 10(4) Da and is composed of fucose and galactose in a ratio of 1:4.12..

Zhu Ling · 2006 · Research Article · Wei sheng wu xue tong bao

Study of the growth rate and comparative analysis of esterase isoenzyme from two isolates of Polyporus umbellatus

Metadata-grounded summary: This research article indexes research on Polyporus umbellatus in Wei sheng wu xue tong bao in 2006. MycoData maps the paper to immune support based on its title, species context, article metadata, and study classification..

Chaga · 2005 · Comparative Study · Journal of ethnopharmacology

Antioxidant effect of Inonotus obliquus.

The mushroom Inonotus obliquus (Fr.) Pilát (Hymenochaetaceae), has been widely used as a folk medicine in Russia, Poland and most of the Baltic countries. The purpose of this study was to elucidate the antioxidant capacities of Inonotus obliquus..

OncologyImmune supportEnergy & fatigueMetabolic health

Chaga · 2005 · Research Support, Non U.S. Gov'T · Journal of ethnopharmacology

In vivo and in vitro anti-inflammatory and anti-nociceptive effects of the methanol extract of Inonotus obliquus.

The mushroom Inonotus obliquus (Fr.) Pilát (Hymenochaetaceae), has been traditionally used for the treatment of gastrointestinal cancer, cardiovascular disease and diabetes in Russia, Poland and most of Baltic countries..

Mesima · 2005 · Patent · journal metadata

LIVESTOCK FEED COMPOSITION CONTAINING PHELLINUS LINTEUS POWDER AND LOESS AS MAIN COMPONENT HAVING EFFECTS OF INCREASING GROWTH RATE OF ANIMALS AS WELL AS IMMUNITY AGAINST DISEASE WHEN FED TO ANIMALS

PURPOSE: A livestock feed composition containing Phellinus linteus powder, loess, cereals, a protein source, fat and oil and one or more additives is provided. It increases activity and growth rate of animals as well as immunity against disease when fed to animals..

Immune supportMetabolic health

Chaga · 2005 · Patent · journal metadata

PREPARATION OF FUNCTIONAL RICE BY COATING PREWASHED RICE WITH EXTRACT OF CHAGA(INONOTUS OBLIQUUS)

PURPOSE: A method of making functional rice coated with a Chaga extract by coating prewashed rice with an extract of Chaga(Inonotus obliquus) is provided. The product is reinforced in [beta]-glucan and water-soluble lignin and has effects of improving immunity and reducing blood sugar levels..

Mesima · 2005 · Patent · journal metadata

PREPARATION OF PHELLINUS LINTEUS BEVERAGE ECONOMICALLY AND IN HIGH YIELD BY EXTRACTION OF PHELLINUS LINTEUS WITH VACUUM TYPE HOT WATER EXTRACTOR

PURPOSE: A method of producing a Phellinus linteus beverage by extracting Phellinus linteus with a vacuum type hot water extractor is provided. It produces the beverage containing high purity beta-glucan components economically and in high yield..

OncologyImmune supportLiver support

Niu-Chang-Chih · 2005 · Patent · journal metadata

Process for preparing antrodia camphorata polysaccharide and antrodia camphorata triterpene with micro-prorous adsorptive resin and its product

The present invention provides preparation process of antrodia camphorata polysaccharide and antrodia camphorata triterpene with adsorptive microporous resin and its product, and relates to chromatographic separation technology with adsorptive microporous resin and extraction of effective Chinese medicine component..

Mesima · 2005 · Patent · journal metadata

RED PEPPER PASTE OBTAINED BY ADDITION OF PHELLINUS LINTEUS POWDER INSTEAD OF WHEAT FLOUR TO RAW MATERIAL FOR RED PEPPER PASTE

PURPOSE: Red pepper paste containing polysaccharides of Phellinus linteus exhibiting an immuno activating effect obtained by inoculating Phellinus linteus mycelium into glutinous rice and then mixing with malt liquid, fermented soybean powder, red pepper powder and salt is provided..

Immune supportGut & microbiome

Maitake · 2004 · Research Support, Non U.S. Gov'T · Yi chuan = Hereditas

[A method for preparation of genomic DNA from Grifola frondosa and construction of a genomic library].

Grifola frondosa, is a valuable medicinal fungus. High quality total genomic DNA is difficult to prepare due to its high polysaccharide content.

OncologyImmune supportEnergy & fatigue

Mesima · 2004 · Comparative Study · Journal of ethnopharmacology

Acidic polysaccharide isolated from Phellinus linteus enhances through the up-regulation of nitric oxide and tumor necrosis factor-alpha from peritoneal macrophages.

Medicinal mushrooms are increasingly used to treat a wide variety of disease processes. Aqueous extract from the fruiting body or mycelia of Phellinus linteus has been reported to produce antitumor and immunomodulatory activities in vivo and in vitro..

Mesima · 2004 · Comparative Study · Journal of ethnopharmacology

Anti-inflammatory and related pharmacological activities of the n-BuOH subfraction of mushroom Phellinus linteus.

This study aimed to elucidate the anti-inflammatory and related activities of mushroom Phellinus linteus. The results show that the EtOH extract of Phellinus linteus (PLE) dose-dependently inhibited the mouse ear edema induced by croton oil..

OncologyImmune supportGut & microbiomeRespiratory

Mesima · 2004 · Patent · journal metadata

ANTICANCER AGENT CONTAINING POLYSACCHARIDE AND MITOMYCIN C EXTRACTED FROM PHELLINUS LINTEUS

PURPOSE: Provided is an anticancer agent containing polysaccharide that is galactomannoglucan and mitomycin C extracted from Phellinus linteus. It is useful for treatment of stomach cancer, breast cancer, colorectal cancer, large intestine cancer and the like..

Chaga · 2004 · Patent · journal metadata

BASE MATERIAL OF SKIN CARE COSMETIC USING INONOTUS OBLIQUUS TO PROTECT SKIN FROM DAMAGE AND IMPROVE SKIN

PURPOSE: Provided is a base material of the skin care cosmetic by using the extract of Inonotus Obliquus which has skin whitening effect, antioxidation effect, immune increasing effect to protect the skin from damage and improve the skin..

Enoki · 2004 · Patent · journal metadata

BEVERAGE AND FEED ADDITIVES CONTAINING CULTURE BROTH OF FLAMMULINA VELUTIPES MYCELIUM AND PRODUCTION THEREOF USING RICE, STARCH, GREEN TEA, PERSIMMON FOR BEVERAGE AND SOYBEAN MEAL, RAW SUGAR, MgSO4 OR WHEY FOR FEED ADDITIVES

PURPOSE: A method of making a drink and feed additives rich in effective ingredients such as immunostimulating ingredients by liquid culturing Flammulina velutipes mycelium is provided. It has excellent productivity and produces products having the flavor and taste of mushrooms as well as excellent body absorption..

Maitake · 2004 · Short Communication · Wei sheng wu xue bao = Acta microbiologica Sinica

Cloning and expression of Grifola frondosa trehalose synthase gene in Escherichia coli

Metadata-grounded summary: This short communication indexes research on Grifola frondosa in Wei sheng wu xue bao = Acta microbiologica Sinica in 2004. MycoData maps the paper to immune support based on its title, species context, article metadata, and study classification..

Mesima · 2004 · Comparative Study · Bioscience, biotechnology, and biochemistry

Comparative Study on the Modulation of IgE and Cytokine Production by Phellinus linteus Grown on Germinated Brown Rice, Phellinus Linteus and Germinated Brown Rice in Murine Splenocytes

We compared the immunomodulating activities in mice of extracts from Phellinus linteus grown on germinated brown rice (PB), Phellinus linteus (PL) alone, and germinated brown rice (BR) alone. The PL, BR and PB-treated mice were administered with the respective extract (2 mg/head/day) by oral gavage for 4 weeks..

Mesima · 2004 · Patent · journal metadata

COMPOSITE ANTICANCER AGENT CONTAINING POLYSACCHARIDE AND ADRIAMYCIN EXTRACTED FORM PHELLINUS LINTEUS

PURPOSE: Provided is a composite anticancer agent containing polysaccharide and adriamycin extracted form Phellinus linteus, thereby reducing adverse side effects of cancer chemotherapy and consequently treating cancer without adverse side effects..

OncologyImmune supportLiver supportRespiratory

Chaga · 2004 · Patent · journal metadata

COMPOSITION COMPRISING EXTRACT OF INONOTUS OBLIQUUS HAVING IMMUNE-ENHANCING AND ANTICANCER ACTIVITIES

PURPOSE: Provided is a pharmaceutical composition comprising the extract of Inonotus obliquus which has immune-enhancing and anticancer activities. The extract of Inonotus obliquus is effectively used for health foods and medicaments for prevention and treatment of adult diseases, such as immunodeficiency diseases and….

Mesima · 2004 · Patent · journal metadata

COSMETIC COMPOSITION CONTAINING NANOPARTICLES OF PHELLINUS LINTEUS EXTRACT

PURPOSE: Provided is a cosmetic composition containing nanoparticles of a phellinus linteus extract to maximize skin care effects, such as skin whitening, anti-oxidation, anti-inflammation, anti-acne, skin cell proliferation and collagen generation..

Chaga · 2004 · Patent · journal metadata

COSMETIC COMPOSITION INCLUDING EXTRACT OF INONOTUS OBLIQUUS, WHICH HAS ANTI-SKIN AGING EFFECT, IN MULTILAMELLAR VESICLE AND PREPARATION METHOD THEREOF

PURPOSE: Provided is a cosmetic composition including the extract of Inonotus obliquus having anti-skin aging effect in a multilamellar vesicle and a preparation method thereof. Therefore, the cosmetic has excellent antioxidation effect, anti-inflammatory effect, cell proliferation effect and the like..

Mesima · 2004 · Patent · journal metadata

EXTRACTION METHOD OF BETA GLUCAN FROM PHELLINUS LINTEUS THROUGH CELL DESTRUCTION AND ENZYME FERMENTATION METHOD

Disclosed herein is a method for extracting and isolating crude beta-glucan as a medically effective ingredient from Phellinus linteus in high yield. Specifically, the method increases the extraction rate of crude beta-glucan from Phellinus linteus through degradation of the fruiting bodies of Phellinus linteus by….

Immune supportGut & microbiome

Mesima · 2004 · Patent · journal metadata

EXTRACTION METHOD OF BETA-GLUCAN FROM PHELLINUS LINTEUS THROUGH CELL DESTRUCTION BY SUPERSONIC WAVE AND ENZYME FERMENTATION METHOD, THEREBY IMPROVING EXTRACTION EFFICIENCY OF BETA-GLUCAN AND OTHER USEFUL COMPONENTS

PURPOSE: An extraction method of beta-glucan from Phellinus linteus through cell destruction and enzyme fermentation method is provided, thereby improving extraction efficiency of beta-glucan and other useful components by making condition to easily digest a substrate by protease and cellulase..

Chaga · 2004 · Patent · journal metadata

FEED COMPOSITION FOR FISH FARMING CONTAINING INONOTUS OBLIQUUS TO PROMOTE THE GROWTH OF FISHES AND STRENGTHEN IMMUNITY IN THE FISHES

PURPOSE: Provided is a feed composition for fish farming which contains Inonotus Obliquus to promote the growth of fishes and strengthen immunity in the fishes. Therefore, it is effective for the prevention of diseases in fishes..

Mesima · 2004 · Patent · journal metadata

LIVESTOCK FEED ADDITIVE USING PHELLINUS LINTEUS CAKE, PHELLINUS LINTEUS AND ACTIVATED CARBON

PURPOSE: A livestock feed additive obtained by mixing Phellinus linteus cake as by-products of a Phellinus linteus extract with activated carbon is provided. It increases the immunity of an animal against disease and utilizes Phellinus linteus cake which has hitherto been discarded..

Chaga · 2004 · Patent · journal metadata

LIVESTOCK FEED COMPOSITION CONTAINING INONOTUS OBLIQUUS, CEREALS, PROTEIN SOURCE AND FAT AND OIL HAVING EFFECT OF ENHANCING VIABILITY, GROWTH AND DISEASE IMMUNITY OF LIVESTOCK WHEN FED TO LIVESTOCK

PURPOSE: A livestock feed composition containing Inonotus obliquus, cereals, protein source and fat and oil as a main component is provided. It enhances viability, growth and disease immunity of livestock when fed to livestock..

Mesima · 2004 · Patent · journal metadata

METHOD FOR PREPARING LIQUOR USING EXTRACT OF PHELLINUS LINTEUS

PURPOSE: A method for preparing liquor using an extract of Phellinus linteus is provided, thereby stably extracting the extract of Phellinus linteus at low temperature and pressure, so that the function of the liquor that improves physiological activity and immunity of human can be improved..

Mesima · 2004 · Patent · journal metadata

METHOD OF EXTRACTING CRUDE BETA GLUCAN FROM PHELLINUS LINTEUS

Disclosed is a method of extracting beneficial ingredients inclusive of crude beta glucan from Phellinus Linteus. The fruit body of Phellinus Linteus is decomposed by ultrasonic wave, the cell walls of the fruit body are disrupted by hydrothermal process, and then enzyme fermentation is performed, whereby crude beta….

Maitake · 2004 · Patent · journal metadata

MICROORGANISM GRIFOLA FRONDOSA HB0071(KCTC 10337BP), METHOD FOR PRODUCING POLYSACCHARIDE FROM THE SAME, AND USE THEREOF

PURPOSE: A microorganism, Grifola frondosa HB0071(KCTC 10337BP), a method for producing polysaccharide from the same, and the use thereof are provided. The polysaccharide has improved water-protecting effect and senescence inhibiting effect..

Mesima · 2004 · Patent · journal metadata

MICROORGANISM PHELLINUS LINTEUS PRODUCING A LARGE QUANTITY OF ANTICANCER POLYSACCHARIDES AND MASS PRODUCTION METHOD THEREOF

PURPOSE: A microorganism Phellinus linteus and a mass production method thereof are provided. The microorganism produces a large quantity of anticancer polysaccharides.

OncologyImmune supportMetabolic health

Mesima · 2004 · Patent · journal metadata

PHARMACEUTICAL COMPOSITION FOR PREVENTION AND TREATMENT OF DISEASES ASSOCIATED WITH ANGIOGENESIS, CONTAINING POLYSACCHARIDE EXTRACTED FROM PHELLINUS LINTEUS

PURPOSE: A pharmaceutical composition containing polysaccharide such as galactomannoglucan extracted from the mycelium of Phellinus linteus as an effective ingredient is provided. The composition can be used for treatment of arthritis, diabetic retinopathy, psoriasis, cancer or the like..

Wood Ear · 2004 · Patent · journal metadata

POLYSACCHARIDE EXTRACT OF AURICULARIA AURICULA-JUDAE WHICH HAS INHIBITING EFFECT ON ATTACHMENT OF HELICOBACTER PYLORI TO GASTRIC PARIETAL CELL, AND FOOD ADDITIVE CONTAINING THE SAME AS ACTIVE INGREDIENT

PURPOSE: Provided are the polysaccharide extract of Auricularia Auricula-judae which has inhibiting effect on the attachment of helicobacter pylori to the gastric parietal cell, and a food additive which contains the same as an active ingredient..

Mesima · 2004 · Patent · journal metadata

PROCESS FOR PREPARING MYCELIUM OF PHELLINUS LINTEUS USING PLANT OIL

PURPOSE: A process for preparing mycelium of Phellinus linteus using plant oil is provided, thereby mass-producing the mycelium of Phellinus linteus containing protein bounded polysaccharide having improved anticancer activity..

Mesima · 2004 · Patent · journal metadata

PRODUCTION SEASONING LIQUID USING MUSHROOMS SUCH AS PHELLINUS LINTEUS, FLAMMULINA VELUTIPES AND TRICHOLOMA MATSUTAKE

PURPOSE: A method for producing seasoning liquid by extracting Phellinus linteus, Flammulina velutipes and Tricholoma matsutake in water is provided. The product containing [beta]-glucan softens the texture of foods while improving the taste and is beneficial to the human health..

OncologyImmune supportGut & microbiome

Mesima · 2004 · Research Support, Non U.S. Gov'T · Cancer letters

Protein-bound polysaccharide from Phellinus linteus induces G2/M phase arrest and apoptosis in SW480 human colon cancer cells.

The cytotoxic mechanism of protein-bound polysaccharide isolated from Phellinus linteus (PL, Mesima) has been investigated. PL inhibited the proliferation and colony formation of SW480 human colon cancer cells.

Immune supportLiver support

Mesima · 2003 · Comparative Study · Biotechnology letters

Inhibition of cytochrome P450 isozymes in rat liver microsomes by polysaccharides derived from Phellinus linteus.

Polysaccharides (0.5, 1 and 3 mg ml(-1)) from cultured broth and mycelia of Phellinus linteus inhibited cytochrome P450 (CYP) 1A1, CYP 1A2, CYP 2B1, and CYP 2E1 activities in rat liver microsomes..

Maitake · 2002 · Patent · journal metadata

Use of extracts of the fungus Grifola frondosa

Cosmetic and/or dermatological skin care composition for e.g. treating aging symptoms or acne contains extracts of Grifola frondosa having skin cell metabolism stimulant and antiinflammatory activity Extracts (I) of the Grifola frondosa fungus is useful in cosmetic and/or dermatological skin care compositions..

Lion's Mane · 2001 · Comparative Study · Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica

[A comparative study on sterols of ethanol extract and water extract from Hericium erinaceus].

OBJECTIVE: To study the pharmaceutic chemical basis of the different medicinal effects, and to compare and analyze the sterols in Hericium erinaceus mycelia and its ethanol extract, water extract derived from solid fermented mycelia..

Immune supportMetabolic health

King Oyster · 1998 · Research Support, Non U.S. Gov'T · Applied and environmental microbiology

Electron and fluorescence microscopy of extracellular glucan and aryl-alcohol oxidase during wheat-straw degradation by Pleurotus eryngii.

The ligninolytic fungus Pleurotus eryngii grown in liquid medium secreted extracellular polysaccharide (87% glucose) and the H2O2-producing enzyme aryl-alcohol oxidase (AAO). The production of both was stimulated by wheat-straw..

OncologyImmune supportGut & microbiomeRespiratory

Turkey Tail · 2026 · Review · Chinese clinical oncology

Clinical evidence on a Coriolus versicolor-based vaginal gel for HPV-related cervical disease: a narrative review.

BACKGROUND AND OBJECTIVE: Human papillomavirus (HPV) infection is the most common sexually transmitted disease worldwide. Its persistence may lead to cervical dysplasia and, eventually, cervical cancer..

Immune supportCognition & nervesEnergy & fatigueRespiratory

Reishi · 2026 · Clinical Trial Protocol · JMIR research protocols

Effectiveness and Safety of a Supplement Containing a Pharmacologically Active Basidiomycete Mushroom for Chronic Fatigue and Post-COVID-19 Fatigue Syndrome: Protocol for a Randomized Controlled Trial.

BACKGROUND: Chronic fatigue syndrome, or myalgic encephalomyelitis, is characterized by persistent, unexplained exhaustion unalleviated by rest, with a pathophysiology distinct from underlying medical conditions..

Immune supportEnergy & fatigue

Cordyceps · 2026 · Video Audio Media · Journal of visualized experiments: JoVE

Effects of Cordyceps Polysaccharides on D-Galactose-induced Renal Senescence.

Chronic kidney disease (CKD) poses a significant global health concern. Aging of renal tubular epithelial cells (RTECs) impairs kidney regeneration and repair and promotes CKD progression through the release of the senescence-associated secretory phenotype (SASP)..